TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Competitive inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using ATP as subst...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:Competitive inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using ATP as subst...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataKi: 7.60nMAssay Description:Competitive inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using ATP as subst...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Competitive inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using ATP as subst...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Competitive inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using ATP as subst...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of rat DYRK1A isolated from brain using KKISGRLSPIMTEQ as substrate and [gamma33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using RRRFRPASPLRGPPK as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of 6xHis-tagged rat DYRK1A (1 to 502 residues) expressed in Escherichia coli BL21(DE3) using FKHR as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of rat recombinant 6His-tagged DYRK1A (1 to 502 residues) catalytic domain expressed in Escherichia coli BL21 (DE3) using KISGRLSPIMTEQ as...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of rat recombinant DYRK1A-GST expressed in Escherichia coli using KKISGRLSPIMTEQ as substrateMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of rat DYRK1A isolated from brain using KKISGRLSPIMTEQ as substrate and [gamma33P]ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of rat recombinant C-terminal truncated GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of rat recombinant C-terminal truncated GST-tagged DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR as substrate and [gamma33P]ATP ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibition of 6xHis-tagged rat DYRK1A (1 to 502 residues) expressed in Escherichia coli BL21(DE3) using FKHR as substrate incubated for 30 mins in pr...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using myelin protein and [33P-gamma]-ATP after 30 mins by scintillation ...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 66nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate and [gamma-33P]ATP after 30 min...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate and [gamma-33P]ATP after 30 min...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of rat recombinant GST-DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Binding affinity to partial length human BRD9 by BROMOscan assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using myelin protein as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(RAT)
Upr 2301, Cnrs
Curated by ChEMBL
Upr 2301, Cnrs
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant rat DYRK1A (1 to 499 residues ) expressed in bacterial expression system using KKISGRLSPIMTEQ as substrate measured after 3...More data for this Ligand-Target Pair