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Found 109 for UniProtKB: Q7RTV7
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144001(3-{4-[1-(2',4'-Dichloro-biphenyl-4-ylcarbamoyl)-he...)
Affinity DataKi:  14nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144020(3-{4-[1-(4-Benzofuran-2-yl-phenylcarbamoyl)-heptyl...)
Affinity DataKi:  17nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144015(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-octyl]...)
Affinity DataKi:  20nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  29nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144002(3-{4-[2-(4-tert-Butyl-phenyl)-2-(2',4'-dichloro-bi...)
Affinity DataKi:  33nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144008(3-{4-[2-(4-Benzofuran-2-yl-phenylcarbamoyl)-2-(4-t...)
Affinity DataKi:  69nMAssay Description:In vitro inhibitory activity against glucagon induced monkey adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144003(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...)
Affinity DataKi:  110nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144016(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi:  144nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144009(3-{4-[1-(4-tert-Butyl-cyclohexyl)-3-(4-trifluorome...)
Affinity DataKi:  254nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144004(3-{4-[2-(Biphenyl-4-ylcarbamoyl)-2-(4-tert-butyl-p...)
Affinity DataKi:  300nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144012(4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-phenyl)-...)
Affinity DataKi:  317nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144006(3-{4-[2-(4-tert-Butyl-phenyl)-2-(quinolin-3-ylcarb...)
Affinity DataKi:  610nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144005(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-hydroxymethyl-p...)
Affinity DataKi:  1.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144011(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-ethyl-phenylcar...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144019(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144000(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-piperidin-1-yl-...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144018(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-pyrazol-1-yl-ph...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144014(3-{4-[2-(4-tert-Butyl-phenyl)-3-(4-ethyl-piperazin...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144010(3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144013(3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144017(3-{4-[2-(4-tert-Butyl-phenyl)-3-oxo-3-(4-p-tolyl-p...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50144007(3-{4-[2-(4-tert-Butyl-phenyl)-2-(3-ethyl-phenylcar...)
Affinity DataKi: >2.00E+3nMAssay Description:In vitro inhibitory activity against glucagon induced human adenylate cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 1/2/3/4/5/6/7/8/9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50227472(CHEMBL2372272)
Affinity DataKi:  4.40E+6nMAssay Description:In vitro antagonist activity of the compound was measured by inhibition of vasopressin-stimulated adenylate cyclase in renal medullary preparation in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50090529(2-[1-(Naphthalene-1-sulfonyl)-1H-indol-6-yl]-octah...)
Affinity DataIC50:  7.20nMAssay Description:Antagonistic activity of the compound evaluated in adenylyl cyclase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128187((1R,3R)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128192((1S,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128210((1R,3R)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128207((1S,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128209((1R,3S)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128203((1R,3S)-3-(6-Amino-purin-9-yl)-cyclopentanecarboxy...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128199((1S,3S)-4-(6-Amino-purin-9-yl)-cyclopent-2-enecarb...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory concentration of the compound against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119826(5-(6-Amino-purin-9-yl)-pentanoic acid hydroxyamide...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory concentration of the compound against type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119832(4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128188((1S,3R)-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl]-...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128206((1S,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119858(2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128191(2-[3-(6-Amino-purin-9-yl)-cyclopentyloxy]-N-hydrox...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119858(2-[(S)-3-((S)-6-Amino-purin-9-yl)-cyclopentyloxy]-...)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128205(2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyloxy]-N-h...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119855(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119855(2-{[(1S,4R)-4-(6-amino-9H-purin-9-yl)cyclopent-2-e...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory concentration of the compound against Type V Adenyl Cyclase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119844(2-{[2-(6-Amino-purin-9-yl)-ethyl]-methyl-amino}-N-...)
Affinity DataIC50:  1.53E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128204((1R,3R)-2-[4-(6-Amino-purin-9-yl)-cyclopent-2-enyl...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128202((1R,3S)-2-[3-(6-Amino-purin-9-yl)-cyclopentyl]-N-h...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50128195((1R,3R)-[3-(6-Amino-purin-9-yl)-cyclopentyl]-aceti...)
Affinity DataIC50:  2.88E+4nMAssay Description:Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 5(Homo sapiens (Human))
Nps Allelix

Curated by ChEMBL
LigandPNGBDBM50119842(6-(6-Amino-purin-9-yl)-hexanoic acid hydroxyamide ...)
Affinity DataIC50:  3.54E+4nMAssay Description:Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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