TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:The inhibitory concentration for 50% was measured on potassium channel complexMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Kv4.3 (unknown origin) assessed as reduction in transient outward potassium current by high throughput clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of Kv4.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of KV4.3 ion channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of Kv4.3 (unknown origin) assessed as reduction in transient outward potassium current by high throughput clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Kv4.3More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin) by patch clamp methodMore data for this Ligand-Target Pair
TargetKv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Kv4.3 by Ion-work electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Kv4.3 expressed in CHO cells by ionworks patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Kv4.3 by Ion-work electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Kv4.3 channel expressed in CHO cells by IONWORKS patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human Kv4.3 by Ion-work electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >3.33E+4nMAssay Description:Inhibition of human Kv4.3 expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of Kv4.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Kv4.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of potassium channel Kv4.3 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
TargetKv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Sage Therapeutics
Curated by ChEMBL
Sage Therapeutics
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human Kv4.3/human KChIP2.2 expressed in CHO cells by automated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of fast sodium current (INa) in Chinese Hamster Ovary (CHO) K1 cells transfected with human Nav1.5 measured using IonWorks Quattro automat...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.58E+6nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.16E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.16E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells transfected with KCNQ1 / Kv1.7 / KvLQT1 and...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+8nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair