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Found 15 of affinity data for UniProtKB/TrEMBL: Q9WV60
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397748(CHEMBL2177155)
Affinity DataIC50:  5nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397743(CHEMBL2177165)
Affinity DataIC50:  10nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397749(CHEMBL2182002)
Affinity DataIC50:  11nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to GSK-3 beta in mouse D3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397742(CHEMBL2177166)
Affinity DataIC50:  37nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397741(CHEMBL2177167)
Affinity DataIC50:  47nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397747(CHEMBL2177157)
Affinity DataIC50:  49nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397745(CHEMBL2177161)
Affinity DataIC50:  76nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397746(CHEMBL2177159)
Affinity DataIC50:  79nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50397744(CHEMBL2177163)
Affinity DataIC50:  87nMAssay Description:Inhibition of GSK3beta-mediated Tau phosphorylation in mouse 3T3 cells after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50229962(1-(4-methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea | ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human GSK-3beta in mouse 3T3 fibroblasts stably expressing four-repeat tau protein assessed as reduction in tau S396 phosphorylation af...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker beta3-tubulin by immunofluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cells assessed as induction of neuron specific marker neurofilament-M by immunofluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Mus musculus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50325986(3-(6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-...)
Affinity DataKd:  126nMAssay Description:Inhibition of GSK-3 beta in mouse D3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed