BindingDB Data by Journal
PMID | Data | Article Title | Citation | Organization | Data Download |
---|---|---|---|---|---|
24194520 | 5 | Evidence of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysis.![]() | J Biol Chem 289: 423-36 (2014) | Universidade Federal do Rio de Janeiro | 2D 3D TSV |
24187139 | 9 | Defining the communication between agonist and coactivator binding in the retinoid X receptor a ligand binding domain.![]() | J Biol Chem 289: 814-26 (2014) | University of Alabama at Birmingham | 2D 3D TSV |
24225950 | 7 | Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor.![]() | J Biol Chem 289: 942-55 (2014) | Genentech Inc | 2D 3D TSV |
24257746 | 6 | A L-lysine transporter of high stereoselectivity of the amino acid-polyamine-organocation (APC) superfamily: production, functional characterization, and structure modeling.![]() | J Biol Chem 289: 1377-87 (2014) | Max Planck Institute of Biophysics | 2D 3D TSV |
24327656 | 9 | The molecular chaperone Hsp70 activates protein phosphatase 5 (PP5) by binding the tetratricopeptide repeat (TPR) domain.![]() | J Biol Chem 289: 2908-17 (2014) | University of Michigan | 2D 3D TSV |
24356970 | 37 | Structure-guided development of specific pyruvate dehydrogenase kinase inhibitors targeting the ATP-binding pocket.![]() | J Biol Chem 289: 4432-43 (2014) | University of Texas Southwestern Medical Center | 2D 3D TSV |
24379401 | 5 | A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer.![]() | J Biol Chem 289: 5208-16 (2014) | Universität Duisburg-Essen | 2D 3D TSV |
24443569 | 4 | The different inhibition mechanisms of OXA-1 and OXA-24 ß-lactamases are determined by the stability of active site carboxylated lysine.![]() | J Biol Chem 289: 6152-64 (2014) | Case Western Reserve University | 2D 3D TSV |
24523409 | 5 | Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.![]() | J Biol Chem 289: 8839-51 (2014) | Karlsruhe Institute of Technology | 2D 3D TSV |
24497639 | 38 | Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.![]() | J Biol Chem 289: 9304-19 (2014) | Bayer HealthCare | 2D 3D TSV |
24634223 | 8 | Trimethylation of histone H3 lysine 36 by human methyltransferase PRDM9 protein.![]() | J Biol Chem 289: 12177-88 (2014) | University of Toronto | 2D 3D TSV |
24634219 | 2 | A novel small-molecule tumor necrosis factor a inhibitor attenuates inflammation in a hepatitis mouse model.![]() | J Biol Chem 289: 12457-66 (2014) | Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College | 2D 3D TSV |
24644281 | 3 | Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor ß/d (PPARß/d) in the brain.![]() | J Biol Chem 289: 12748-58 (2014) | Case Western Reserve University School of Medicine | 2D 3D TSV |
24695735 | 6 | The Parkinson disease-linked LRRK2 protein mutation I2020T stabilizes an active state conformation leading to increased kinase activity.![]() | J Biol Chem 289: 13042-53 (2014) | Harvard NeuroDiscovery Center | 2D 3D TSV |
24648521 | 2 | Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance.![]() | J Biol Chem 289: 13273-83 (2014) | St. Paul's Hospital's Centre of Heart and Lung Innovation | 2D 3D TSV |
24668804 | 7 | Biochemical, cellular, and biophysical characterization of a potent inhibitor of mutant isocitrate dehydrogenase IDH1.![]() | J Biol Chem 289: 13717-25 (2014) | National Institutes of Health | 2D 3D TSV |
24737316 | 18 | Structural basis of pharmacological chaperoning for human ß-galactosidase.![]() | J Biol Chem 289: 14560-8 (2014) | The University of Tokyo | 2D 3D TSV |
24692551 | 18 | Structural basis for ligand regulation of the fatty acid-binding protein 5, peroxisome proliferator-activated receptor ß/d (FABP5-PPARß/d) signaling pathway.![]() | J Biol Chem 289: 14941-54 (2014) | Emory University | 2D 3D TSV |
24753254 | 2 | Functional rescue of Kallmann syndrome-associated prokineticin receptor 2 (PKR2) mutants deficient in trafficking.![]() | J Biol Chem 289: 15518-26 (2014) | Central South University | 2D 3D TSV |
24742680 | 14 | Structural basis for the recognition of peptide RJPXD33 by acyltransferases in lipid A biosynthesis.![]() | J Biol Chem 289: 15527-35 (2014) | University of Michigan | 2D 3D TSV |
24742681 | 4 | Oxysterol-binding protein (OSBP)-related protein 4 (ORP4) is essential for cell proliferation and survival.![]() | J Biol Chem 289: 15705-17 (2014) | Dalhousie University | 2D 3D TSV |
24739388 | 14 | Rational design of broad spectrum antibacterial activity based on a clinically relevant enoyl-acyl carrier protein (ACP) reductase inhibitor.![]() | J Biol Chem 289: 15987-6005 (2014) | University of Wuerzburg | 2D 3D TSV |
24719329 | 3 | Inhibition of the ribonuclease H activity of HIV-1 reverse transcriptase by GSK5750 correlates with slow enzyme-inhibitor dissociation.![]() | J Biol Chem 289: 16270-7 (2014) | McGill University | 2D 3D TSV |
24755226 | 6 | Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.![]() | J Biol Chem 289: 16349-61 (2014) | University of Colorado School of Medicine | 2D 3D TSV |
24782313 | 10 | In vitro resistance selections for Plasmodium falciparum dihydroorotate dehydrogenase inhibitors give mutants with multiple point mutations in the drug-binding site and altered growth.![]() | J Biol Chem 289: 17980-95 (2014) | Harvard School of Public Health | 2D 3D TSV |
24798337 | 5 | Human UTY(KDM6C) is a male-specific N¿-methyl lysyl demethylase.![]() | J Biol Chem 289: 18302-13 (2014) | University of Oxford | 2D 3D TSV |
24847082 | 6 | Opioid receptor function is regulated by post-endocytic peptide processing.![]() | J Biol Chem 289: 19613-26 (2014) | Icahn School of Medicine at Mount Sinai | 2D 3D TSV |
24891505 | 6 | Two amino acid residues confer different binding affinities of Abelson family kinase SRC homology 2 domains for phosphorylated cortactin.![]() | J Biol Chem 289: 19704-13 (2014) | Yale University | 2D 3D TSV |
24831010 | 11 | ORA1, a zebrafish olfactory receptor ancestral to all mammalian V1R genes, recognizes 4-hydroxyphenylacetic acid, a putative reproductive pheromone.![]() | J Biol Chem 289: 19778-88 (2014) | German Institute of Human Nutrition Potsdam-Rehbruecke | 2D 3D TSV |
24860094 | 14 | Structure of the Acinetobacter baumannii dithiol oxidase DsbA bound to elongation factor EF-Tu reveals a novel protein interaction site.![]() | J Biol Chem 289: 19869-80 (2014) | University of Queensland | 2D 3D TSV |
24872411 | 2 | Structure of REV-ERBß ligand-binding domain bound to a porphyrin antagonist.![]() | J Biol Chem 289: 20054-66 (2014) | The Scripps Research Institute | 2D 3D TSV |
24917667 | 36 | Digoxin derivatives with enhanced selectivity for the a2 isoform of Na,K-ATPase: effects on intraocular pressure in rabbits.![]() | J Biol Chem 289: 21153-62 (2014) | Weizmann Institute of Science | 2D 3D TSV |
24936059 | 26 | The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability.![]() | J Biol Chem 289: 21651-62 (2014) | AstraZeneca R&D Boston | 2D 3D TSV |
24962584 | 2 | Chemical proteomics identifies heterogeneous nuclear ribonucleoprotein (hnRNP) A1 as the molecular target of quercetin in its anti-cancer effects in PC-3 cells.![]() | J Biol Chem 289: 22078-89 (2014) | National Taiwan University | 2D 3D TSV |