Search by Compound Name


Compound Name:

Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
2 IC50 13 EC50
  • HIV-1 Reverse Transcriptase
  • Human immunodeficiency virus type 1 reverse transcriptase
  • 3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),6,8,10-tetraene
  • CHEMBL53554
  • NSC 625487
  • TBZ
  • Thiazolobenzimidazole
15 IC50
  • 5'-AMP-activated protein kinase subunit beta-1
  • ALK1
  • ALK2
  • ALK3
  • ALK4
  • ALK5
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein 4
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Bone morphogenetic protein receptor type-2
  • Serine/threonine-protein kinase receptor R3
  • TGF-beta receptor type II
  • TGF-beta receptor type-1
  • LDN-212854
15 Ki
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 9
  • beta-Carbonic Anhydrase
  • 2-methoxy-N-[(1-methylpyrrolidin-2-yl)methyl]-5-sulfamoylbenzamide
  • Sulmepride
  • Sulpiride (SLP)
1 Ki 14 IC50
  • Acetylcholinesterase
  • Cholinesterase
  • Cholinesterases
  • 3-(4-{[Benzyl(methyl)amino]methyl}-phenyl)-6,7-dimethoxy-2H-2-chromenone
  • 3-(4-{[benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-chromen-2-one
  • AP2238
  • CHEMBL75121
14 IC50 1 EC50
  • Acetylcholinesterase
  • Carboxylic ester hydrolase
  • Cholinesterases
  • (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-phenylcarbamate
  • CHEMBL74926
  • US10864192, Compound (-)-Phenserine
  • phenserine
  • phenserine.tartaric acid
1 Ki 14 IC50
  • Acetylcholinesterase
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Cholinesterases
  • Genome polyprotein
  • (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate; 2-hydroxybenzoic acid
  • Eserine
  • cid_657348
  • physostigmine.salicylic acid
15 Ki
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Astrosclerin-3
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • β-CA inhibitor, 10
  • 4-Amino-3,5-dibromobenzenesulfonamide
  • 4-amino-3,5-dibromobenzene-1-sulfonamide
  • CHEMBL306195
  • halogenosulfanilamide deriv. 12
15 Ki
  • Cathepsin K
  • Cathepsin S
  • Procathepsin L
  • US10723709, Example 1
  • US8735395, 1
  • US9200006, 1
15 Ki
  • Cathepsin K
  • Cathepsin S
  • Procathepsin L
  • US10723709, Example 2
  • US8735395, 2
  • US9200006, 2
3 Ki 12 IC50
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
  • CHEMBL178090
  • US8609708, 2
  • US8609708, 47
  • [5-(pyridin-3-yl)furan-2-yl]methanamine
  • nicotine 3-heteroaromatic analogue 2a
3 Ki 12 IC50
  • Cytochrome P450 1A
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
  • 3-(pyridin-3-yl)prop-2-yn-1-amine
  • CHEMBL360541
  • US8609708, 3
  • nicotine 3-heteroaromatic analogue 3a
3 Ki 12 IC50
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
  • Indoleamine 2,3-dioxygenase
  • 3-(1H-imidazol-4-yl)pyridine
  • CHEMBL178516
  • JMC514968 Compound 7
  • US8609708, 14
  • US8609708,14
  • nicotine 3-heteroaromatic analogue 10
3 Ki 12 IC50
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Serine/threonine-protein kinase Aurora-C
  • Tyrosine-protein kinase ABL1
  • 5-Amido-pyrrolopyrazole 9d
  • CHEMBL402548
  • N-{5-[(2R)-2-methoxy-2-phenylacetyl]-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-yl}-4-(4-methylpiperazin-1-yl)benzamide
15 IC50
  • Anandamide amidohydrolase
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Fatty-acid amide hydrolase 1
  • US9682953, 20.A-10
  • US9682953, 20.A-9
15 IC50
  • Sodium channel protein type 5 subunit alpha
  • Sodium channel protein type 9 subunit alpha
  • US8952169, 6
  • US9771376, Example 6
15 IC50
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • US10081622, Compound 4
  • US9029356, 4
  • US9255087, 4
  • US9616059, 4
15 IC50
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • US10081622, Compound 26
  • US9029356, 26
  • US9255087, 26
  • US9616059, 26
3 Ki 11 IC50 1 Kd
  • Apoptosis regulator Bcl-2
  • Baculoviral IAP repeat-containing protein 2
  • Cytochrome P450 3A
  • E3 ubiquitin-protein ligase Mdm2
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • MDM2-MDMX
  • X-linked inhibitor of apoptosis protein (XIAP)
  • p53-Binding Protein HDMX
  • US9051279, 106
15 Ki
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US9062078, 195
  • US9475819, 195
  • US9637496, 379
  • US9695183, 195
15 Ki
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US9062078, 210
  • US9475819, 235
  • US9637496, 210
  • US9695183, 210
  • US9695183, 235
15 Ki
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US9062078, 266
  • US9475819, 266
  • US9637496, 409
  • US9695183, 266
15 IC50
  • Cytoplasmic tyrosine-protein kinase BMX
  • Receptor protein-tyrosine kinase erbB-4
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • US10604504, Example 5
  • US9688629, 5
  • US9802915, Example 22
  • US9920031, Example 5
15 IC50
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/Cyclin A1
  • CDK3/E
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 3 (CDK3)
  • Cyclin-dependent kinase 6
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • Glycogen synthase kinase-3
  • Interleukin-1 receptor-associated kinase 1
  • US9067888, 33
12 IC50 1 Kd
0 ΔG°
  • Aldehyde reductase
  • Aldose Reductase (ALR2) Mutant (L300P)
  • Aldose reductase
  • Aldose reductase (AR)
  • (2S,4S)-6-fluoro-2',5'-dioxo-2,3-dihydrospiro[1-benzopyran-4,4'-imidazolidine]-2-carboxamide
  • (2S,4S)-6-fluoro-2,5-dioxo-2,3-dihydrospiro[chromene-4,4-imidazolidine]-2-carboxamide
  • CHEMBL84446
  • Fidarestat
  • Fidarestat (1)
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10323032, Example 66
  • US9096596, 66
  • US9604982, Example 66
15 IC50
  • Dihydrofolate reductase
  • Thymidylate Synthase (TS)
  • Thymidylate synthase
  • 2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one
  • CHEMBL400364
  • Pyrrolo[2,3-d]pyrimidine analogue, 2
15 IC50
  • Dihydrofolate reductase
  • Thymidylate Synthase (TS)
  • Thymidylate synthase
  • 2-amino-5-[(3,4-dichlorophenyl)sulfanyl]-6-methyl-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one
  • CHEMBL400485
  • Pyrrolo[2,3-d]pyrimidine analogue, 3
15 Ki
  • Nitric Oxide Synthase, brain Mutant (D597N)
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase mutant (nNOS M336V/D597N)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
  • Nitric-oxide synthase, endothelial
  • US10759791, Compound 14g
  • nNOS inhibitor, 3
15 Ki
  • Nitric Oxide Synthase, brain Mutant (D597N)
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase mutant (nNOS M336V/D597N)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
  • Nitric-oxide synthase, endothelial
  • US10759791, Compound 14h
  • nNOS inhibitor, 4
15 Ki
  • Nitric Oxide Synthase, brain Mutant (D597N)
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase mutant (nNOS M336V/D597N)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
  • Nitric-oxide synthase, endothelial
  • US10759791, Compound 14k
  • nNOS inhibitor, 6
15 IC50
  • Bromodomain-containing protein 4
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 4
  • Cereblon/Histone deacetylase 6
  • Histone Deacetylase 6 (HDAC6)
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
  • Histone deacetylase 4
  • (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
  • Antibiotic FR 901228
  • CHEMBL343448
  • Depsipeptide
  • FK228
  • Romidepsin
13 IC50 2 Kd
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5A (KDM5A(aa 1-1090)-Flag)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-588)ΔAP)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-739)ΔAP(2C-2S))
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5B (KDM5B(aa 1-604)ΔAP)
  • Lysine-specific demethylase 5B (KDM5B(aa 1-755)ΔAP)
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 5C (KDM5C(aa 1-789)ΔAP)
  • Lysine-specific demethylase 5D (KDM5D(aa 1-760)ΔAP)
  • 6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (N8)
12 IC50 3 EC50
  • Isocitrate dehydrogenase [NADP] cytoplasmic
  • L-lactate dehydrogenase A chain
  • L-lactate dehydrogenase B chain
  • Lactate dehydrogenase A (LDHA)
  • Lactate dehydrogenase B (LDHB)
  • GNE-140 (6)
0 ΔG°
  • SAMPL4, OA
14 IC50 1 EC50
  • B-RAF V600E
  • C-RAF
  • RAF proto-oncogene serine/threonine-protein kinase
  • Serine/threonine-protein kinase B-raf
  • US10245267, Example 62
  • US10709712, Example 62
  • US9242969, 62
  • US9694016, 62
14 IC50 1 EC50
  • B-RAF V600E
  • C-RAF
  • RAF proto-oncogene serine/threonine-protein kinase
  • Serine/threonine-protein kinase B-raf
  • US10245267, Example 117
  • US10709712, Example 117
  • US9242969, 117
  • US9694016, 117
14 IC50 1 EC50
  • B-RAF V600E
  • C-RAF
  • RAF proto-oncogene serine/threonine-protein kinase
  • Serine/threonine-protein kinase B-raf
  • US10245267, Example 134
  • US10709712, Example 134
  • US9242969, 134
  • US9694016, 134
14 IC50 1 EC50
  • B-RAF V600E
  • C-RAF
  • RAF proto-oncogene serine/threonine-protein kinase
  • Serine/threonine-protein kinase B-raf
  • US10245267, Example 138
  • US10709712, Example 138
  • US9242969, 138
  • US9694016, 138
14 IC50 1 EC50
  • B-RAF V600E
  • C-RAF
  • RAF proto-oncogene serine/threonine-protein kinase
  • Serine/threonine-protein kinase B-raf
  • US10245267, Example 145
  • US10709712, Example 145
  • US9242969, 145
  • US9694016, 145
15 IC50
  • B-RAF V600E
  • Poly [ADP-ribose] polymerase 1
  • Poly [ADP-ribose] polymerase 2
  • Poly [ADP-ribose] polymerase 3 (PARP-3)
  • Poly [ADP-ribose] polymerase tankyrase-2
  • Protein mono-ADP-ribosyltransferase PARP3
  • TPoly [ADP-ribose] polymerase tankyrase-2
  • US10501467, Example 2
  • US9260440, 1
  • US9617273, Example 1
15 IC50
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 3A
  • DNA Gyrase
  • DNA Topoisomerase IV
  • DNA gyrase subunit A
  • DNA gyrase subunit B
  • DNA topoisomerase II
  • Multidrug resistance-associated protein 4
  • 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
  • Nalidixic Acid
  • Nalidixin
  • NegGram
  • Nevigramon
  • US9138393, Nalidixic acid
  • US9144538, Nalidixic acid
5 Ki 9 IC50 1 EC50
  • Androgen Receptor
  • Bile acid receptor
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • Nuclear receptor subfamily 1 group I member 2
  • Progesterone receptor
  • (1S,2R,10R,11S,14Z,15S)-14-ethylidene-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-ene-5,13-dione
  • Guggulsterone
2 Ki 12 IC50
0 ΔG°
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Cytochrome P450 3A
  • Dihydrofolate reductase
  • Indoleamine 2,3-dioxygenase
  • Intestinal alkaline phosphatase
  • Large neutral amino acids transporter small subunit 1
  • Myeloperoxidase
  • Phospholipase A-2-activating protein
  • Stromelysin-1
  • Tryptophan 2,3-dioxygenase
  • Uracil nucleotide/cysteinyl leukotriene receptor
  • (2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
  • CHEMBL54976
  • L-tryptophan
  • US9138393, L-Tryptophan
  • US9144538, L-Tryptophan
11 Ki 2 IC50 2 EC50
  • Neuronal acetylcholine receptor
  • Neuronal acetylcholine receptor Alpha-2/Beta-4
  • Neuronal acetylcholine receptor Alpha-3/Beta-2
  • Neuronal acetylcholine receptor Alpha-3/Beta-4
  • Neuronal acetylcholine receptor Alpha-4/Beta-2
  • Neuronal acetylcholine receptor protein alpha-2/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit
  • Neuronal acetylcholine receptor; alpha3/beta4
  • nAChR alpha4 beta2 subtype
  • US9284322, varenicline
  • US9303017, Varenicline
15 IC50
  • SYK Kinase
  • GTC000228A
  • GTC000228B
  • GTC000228C
13 Ki 2 IC50
  • Acetylcholinesterase
  • Acyl-CoA: cholesterol acyltransferase (ACAT)
  • Carboxylesterase 1
  • Carboxylesterase 2
  • Cholinesterases
  • Factor XIIa
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • 2-hydroxy-1,2-diphenylethan-1-one
  • Benzoin
  • CHEMBL190677
11 IC50 3 Kd 1 EC50
  • Heat shock protein HSP 90-alpha
  • Heat-shock protein 90 (Hsp90)
  • Pyruvate dehydrogenase kinase
  • Pyruvate dehydrogenase kinase 3 (PDK3)
  • Pyruvate dehydrogenase kinase 4 (PDK4)
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial
  • PS10
9 Ki 5 IC50 1 EC50
  • Acetylcholinesterase
  • Acyl-CoA: cholesterol acyltransferase (ACAT)
  • Aldehyde dehydrogenase 1A1 (ALDH1A1)
  • Aldehyde dehydrogenase 3A1 (ALDH3A1)
  • Aldehyde dehydrogenase, mitochondrial
  • Carboxylesterase 1
  • Cholinesterases
  • Factor XIIa
  • Muscarinic acetylcholine receptor M1
  • 1-benzyl-2,3-dihydro-1H-indole-2,3-dione
  • Isatin-based compound, 14
1 Ki 14 IC50
  • 15-Lipoxygenase (LoxA)
  • 5-hydroxytryptamine receptor 1A
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(2) dopamine receptor
  • Histamine H1 receptor
  • Histamine H4 receptor
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily H member 2
  • Replicase polyprotein 1ab
  • 1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one
  • Bactil
  • CHEMBL305660
  • Ebastine
  • Kestine
  • NCGC00164603
15 IC50
  • Dual-specificity phosphatase 5 phophatase (DUSP5)
  • 1-Amin-5-Naphthol-7-Sulfonic acid
  • NCI2602
  • RR535
10 IC50 4 EC50
0 ΔG°
  • HIV-1 Reverse Transcriptase
  • Human immunodeficiency virus type 1 reverse transcriptase
  • Reverse transcriptase
  • Reverse transcriptase (HIV-1 RT)(1-350)
  • 6-benzyl-1-(ethoxymethyl)-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • CHEMBL35033
  • Coactinon
  • Emivirine
  • Emivirine (EMV)
  • HEPT deriv.
  • I-EBU
  • MKC-442
3 Ki 11 IC50 0 Other
  • Aurora kinase B
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • Inositol hexakisphosphate kinase 2
  • Inositol polyphosphate multikinase
  • Lysine-specific histone demethylase 1A
  • Mitogen-activated protein kinase 10
  • Mitogen-activated protein kinase 14
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 2 (MRP2)
  • alpha-Amylase
  • 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one
  • Diosmetin
  • Diosmetin (25)
9 Ki 6 IC50
  • Adenosine kinase
  • Equilibrative Nucleoside Transporter 1 (ENT1)
  • Equilibrative nucleoside transporter 1
  • Multidrug resistance-associated protein 4
  • Solute carrier family 28 member 3
  • (2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-{[(4-nitrophenyl)methyl]sulfanyl}-9H-purin-9-yl)oxolane-3,4-diol
  • 4-nitrobenzylmercaptopurine ribonucleoside
  • CHEMBL418509
  • NBMPR
  • NBTI
  • Nitrobenzylthioinosine
15 IC50
  • Coagulation factor X
  • Coagulation factor XI
  • Prothrombin
  • US10336741, Example 98
  • US10882855, Example 98
  • US9394250, 98
  • US9585881, Example 98
12 IC50 3 Kd
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Serine/threonine-protein kinase PIM
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • Serine/threonine-protein kinase pim-3
  • US9394297, 450
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 14
  • US10836768, Cpd no 14
  • US9422299, 14
  • US9987274, Compound 14
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 19
  • US10836768, Cpd no 19
  • US9422299, 19
  • US9987274, Compound 19
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 25
  • US10836768, Cpd no 25
  • US9422299, 25
  • US9987274, Compound 25
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 26
  • US10836768, Cpd no 26
  • US9422299, 26
  • US9987274, Compound 26
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 31
  • US10836768, Cpd no 31
  • US9422299, 31
  • US9987274, Compound 31
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 32
  • US10836768, Cpd no 32
  • US9422299, 32
  • US9987274, Compound 32
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 33
  • US10836768, Cpd no 33
  • US9422299, 33
  • US9987274, Compound 33
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 34
  • US10836768, Cpd no 34
  • US9422299, 34
  • US9987274, Compound 34
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 35
  • US10836768, Cpd no 35
  • US9422299, 35
  • US9987274, Compound 35
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 36
  • US10836768, Cpd no 36
  • US9422299, 36
  • US9987274, Compound 36
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 37
  • US10836768, Cpd no 37
  • US9422299, 37
  • US9987274, Compound 37
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 38
  • US10836768, Cpd no 38
  • US9422299, 38
  • US9987274, Compound 38
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 39
  • US10836768, Cpd no 39
  • US9422299, 39
  • US9987274, Compound 39
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 40
  • US10836768, Cpd no 40
  • US9422299, 40
  • US9987274, Compound 40
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 42
  • US10836768, Cpd no 42
  • US9422299, 42
  • US9987274, Compound 42
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 43
  • US10836768, Cpd no 43
  • US9422299, 43
  • US9987274, Compound 43
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 44
  • US10836768, Cpd no 44
  • US9422299, 44
  • US9987274, Compound 44
12 Ki 3 IC50
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • hnk-3
  • US10030025, Compound 45
  • US10836768, Cpd no 45
  • US9422299, 45
  • US9987274, Compound 45
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(4,4- difluorocyclohexyl)- 5-((1R,2R)-2- (tetrahydro-2H- pyran-4-ylamino)- cyclopropyl)thio- phene-3-carboxamide
  • US10053456, 44
  • US10414761, Example 44
  • US9718814, 44
  • US9920047, 44
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2-((4,4- difluorocyclohexyl)- amino)cyclopropyl)- N-(tetrahydro-2H- pyran-4- yl)thiophene-3- carboxamide
  • US10053456, 47
  • US10414761, Example 47
  • US9718814, 47
  • US9920047, 47
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2-((1- cyclopropylpiperi- din-4-yl)amino)- cyclopropyl)-N-(5- methyl-1,3,4- thiadiazol-2-yl)thiophene-3-carboxamide
  • US10053456, 48
  • US10414761, Example 48
  • US9718814, 48
  • US9920047, 48
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(5-methyl-1,3,4- thiadiazol-2-yl)-5- ((1R,2R)-2- (tetrahydro-2H- pyran-4-ylamino)- cyclopropyl)thio- phene-3-carboxamide
  • US10053456, 49
  • US10414761, Example 49
  • US9718814, 49
  • US9920047, 49
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(2-methyl-1,3- thiazol-5-yl)-5- ((1R,2R)-2- (tetrahydro-2H- pyran-4-ylamino)- cyclopropyl)thio- phene-3-carboxamide
  • US10053456, 50
  • US10414761, Example 50
  • US9718814, 50
  • US9920047, 50
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(4,4- difluorocyclohexyl)- 5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide
  • US10053456, 51
  • US10414761, Example 51
  • US9718814, 51
  • US9920047, 51
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- N-(1-(2,2,2- trifluoroethyl)- piperidin-4- yl)thiophene-3- carboxamide
  • US10053456, 52
  • US10414761, Example 52
  • US9718814, 52
  • US9920047, 52
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(2-methyl-1,3- thiazol-5-yl)-5- ((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide
  • US10053456, 53
  • US10414761, Example 53
  • US9718814, 53
  • US9920047, 53
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(1,3-dimethyl-1H- pyrazol-4-yl)-5- ((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide
  • US10053456, 54
  • US10414761, Example 54
  • US9718814, 54
  • US9920047, 54
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(1,5-dimethyl-1H- pyrazol-4-yl)-5- ((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide
  • US10053456, 55
  • US10414761, Example 55
  • US9718814, 55
  • US9920047, 55
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 3-(4-((((1R,2R)-2- (4-((5-methyl-1,3,4- thiadiazol-2-yl)- carbamoyl)-2- thienyl)cyclopropyl) amino)methyl)- piperidin-1- yl)propanoic acid
  • US10053456, 60
  • US10414761, Example 60
  • US9718814, 60
  • US9920047, 60
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 4-(trans-2- (cyclobutylamino)- cyclopropyl)-N-(1- methyl-1H-pyrazol-4- yl)thiophene-2- carboxamide
  • US10053456, 61
  • US10414761, Example 61
  • US9718814, 61
  • US9920047, 61
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2-((1- cyclopropyl- piperidin-4-yl)- amino)cyclopropyl)- N-(4,4- difluorocyclohexyl)- thiophene-3-carboxamide
  • US10053456, 80
  • US10414761, Example 80
  • US9718814, 80
  • US9920047, 80
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(5-methyl-1,2- oxazol-3-yl)-5- ((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide
  • US10053456, 81
  • US10414761, Example 81
  • US9718814, 81
  • US9920047, 81
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • N-(1-ethyl-1H- pyrazol-4-yl)-5- ((1R,2R)-2- ((tetrahydro-2H- pyran-4-ylmethyl)- amino)cyclopropyl)- thiophene-3- carboxamide
  • US10053456, 86
  • US10414761, Example 86
  • US9718814, 86
  • US9920047, 86
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2-((1- acetylpiperidin-4- yl)amino)cyclo- propyl)-N-(4,4- difluorocyclohexyl)- thiophene-3- carboxamide
  • US10053456, 91
  • US10414761, Example 91
  • US9718814, 91
  • US9920047, 91
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2-((1- (cyclopropyl- carbonyl)piperidin- 4-yl)amino)- cyclopropyl)-N-(4,4- difluorocyclohexyl)- thiophene-3-carboxamide
  • US10053456, 92
  • US10414761, Example 92
  • US9718814, 92
  • US9920047, 92
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 4-((4-((((1R,2R)-2- (4-((4,4-difluoro- cyclohexyl)- carbamoyl)-2- thienyl)cyclo- propyl)amino)methyl) piperidin-1- yl)methyl)benzoic acid
  • US10053456, 101
  • US10414761, Example 101
  • US9718814, 101
  • US9920047, 101
15 IC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Lysine-specific histone demethylase 1A
  • 5-((1R,2R)-2- ((cyclobutylmethyl)- amino)cyclopropyl)- N-(tetrahydro-2H- pyran-4- yl)thiophene-3- carboxamide
  • US10053456, 112
  • US10414761, Example 112
  • US9718814, 112
  • US9920047, 112
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 32
  • US9434690, 30
  • US9434690, 31
  • US9434690, 32
  • US9822102, Example 32
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 37
  • US9434690, 35
  • US9434690, 36
  • US9434690, 37
  • US9822102, Example 37
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 47
  • US9434690, 45
  • US9434690, 46
  • US9434690, 47
  • US9822102, Example 47
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 57
  • US9434690, 55
  • US9434690, 56
  • US9434690, 57
  • US9822102, Example 57
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 65
  • US9434690, 63
  • US9434690, 64
  • US9434690, 65
  • US9822102, Example 65
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 78
  • US9434690, 76
  • US9434690, 77
  • US9434690, 78
  • US9822102, Example 78
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 81
  • US9434690, 79
  • US9434690, 80
  • US9434690, 81
  • US9822102, Example 81
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 86
  • US9434690, 84
  • US9434690, 85
  • US9434690, 86
  • US9822102, Example 86
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 96
  • US9434690, 94
  • US9434690, 95
  • US9434690, 96
  • US9822102, Example 96
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 115
  • US9434690, 113
  • US9434690, 114
  • US9434690, 115
  • US9822102, Example 115
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 138
  • US9434690, 136
  • US9434690, 137
  • US9434690, 138
  • US9822102, Example 138
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 154
  • US9434690, 152
  • US9434690, 153
  • US9434690, 154
  • US9822102, Example 154
15 IC50
  • Coagulation factor XI
  • Plasma kallikrein
  • US10183932, Example 157
  • US9434690, 155
  • US9434690, 156
  • US9434690, 157
  • US9822102, Example 157
15 IC50
  • JAK1 (aa 837-1142)
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Mer
  • US10053465, 9
  • US10065963, Compound 9
  • US10125150, Example 9
  • US10336759, # 9
  • US10479803, Example 9
  • US10675284, Example 9
  • US9732097, Example 9
  • US9999619, Example 86
  • [3-[4-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1-yl]-1- (1-{[2- (trifluoromethyl) pyrimidin-4- yl]carbonyl} piperidin-4-yl) azetidin-3- yl]acetonitrile
15 IC50
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • US10053465, 10
  • US10065963, Compound 10
  • US10125150, Example 10
  • US10336759, # 10
  • US10479803, Example 10
  • US10519163, Example 10
  • US10675284, Example 10
  • US9732097, Example 10
  • [trans-1-[4-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1-yl]-3- (4-{[2- (trifluoromethyl) pyrimidin-4- yl]carbonyl} piperazin-1- yl)cyclobutyl] acetonitrile
15 IC50
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • US10053465, 18
  • US10065963, Compound 18
  • US10125150, Example 18
  • US10336759, # 18
  • US10479803, Example 18
  • US10519163, Example 18
  • US10675284, Example 18
  • US9732097, Example 18
  • {1-(cis-4-{[6-(2- hydroxyethyl)-2- (trifluoromethyl) pyrimidin-4- yl]oxy}cyclohexyl)- 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]azetidin-3- yl}acetonitrile
15 IC50
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • US10053465, 19
  • US10065963, Compound 19
  • US10125150, Example 19
  • US10336759, # 19
  • US10479803, Example 19
  • US10519163, Example 19
  • US10675284, Example 19
  • US9732097, Example 19
  • {1-(cis-4-{[4- [(ethylamino) methyl]-6- (trifluoromethyl) pyridin-2- yl]oxy}cyclohexyl)- 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]azetidin-3- yl}acetonitrile
15 IC50
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • US10053465, 23
  • US10065963, Compound 23
  • US10125150, Example 23
  • US10336759, # 23
  • US10479803, Example 23
  • US10519163, Example 23
  • US10675284, Example 23
  • US9732097, Example 23
  • {trans-3-(4-{[4- ({[(1S)-2-hydroxy-1- methylethyl]amino} methyl)-6- (trifluoromethyl) pyridin-2- yl]oxy}piperidin-1- yl)-1-[4-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]cyclobutyl} acetonitrile
15 IC50
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • 5-{3-[1-(4-amino-3- methyl-1H-pyrazolo[3,4 d]pyrimidin-1-yl)ethyl]- 6-cyano-2-ethoxy-5- methylphenyl}-N,N- dimethylpyridine-2- carboxamide
  • US10053465, 31
  • US10065963, Compound 31
  • US10376513, Example 344
  • US10519163, Example 31
  • US10646492, Example 314
  • US10675284, Example 31
  • US9730939, Example 314
12 Ki 3 IC50
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • Serine/threonine-protein kinase pim-3
  • US9434725, 210
  • US9434725, 211
  • US9434725, 212
  • US9434725, 213
15 IC50
  • Epidermal growth factor receptor
  • Tyrosine-protein kinase BTK
  • US10005782, Compound 6b
  • US9447106, 6
  • US9556188, Compound 6
15 IC50
  • Epidermal growth factor receptor
  • Tyrosine-protein kinase BTK
  • US10005782, Compound 20b
  • US9447106, 20
  • US9556188, Compound 20
15 IC50
  • Epidermal growth factor receptor
  • Tyrosine-protein kinase BTK
  • US10005782, Compound 94
  • US9447106, 94
  • US9556188, Compound 94
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 4
  • US10150765, Example 4
  • US10703749, Example 4
  • US9464084, 4
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 5
  • US10150765, Example 5
  • US10703749, Example 5
  • US9464084, 5
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 14
  • US10150765, Example 14
  • US10703749, Example 14
  • US9464084, 14
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 15
  • US10150765, Example 15
  • US10703749, Example 15
  • US9464084, 15
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 16
  • US10150765, Example 16
  • US10703749, Example 16
  • US9464084, 16
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 19
  • US10150765, Example 19
  • US10703749, Example 19
  • US9464084, 19
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 20
  • US10150765, Example 20
  • US10703749, Example 20
  • US9464084, 20
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 24
  • US10150765, Example 24
  • US10703749, Example 24
  • US9464084, 24
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 25
  • US10150765, Example 25
  • US10703749, Example 25
  • US9464084, 25
5 Ki 10 IC50
  • P2X purinoceptor 7
  • P2X purinoceptor 7 (P2X7)
  • US10112937, Example 26
  • US10150765, Example 26
  • US10703749, Example 26
  • US9464084, 26
Displayed 1 to 50 (of 365 total ) | Next | Last >>