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Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
9 Ki 141 IC50 2 EC50
  • Adenosine receptor A2
  • Bile salt export pump
  • Calcium channel (Type L)
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Heart phosphodiesterase
  • Indoleamine 2,3-dioxygenase 1
  • Indoleamine 2,3-dioxygenase 2
  • Multidrug resistance-associated protein 4
  • Multidrug resistance-associated protein 5
  • Phosphodiesterase (TcrPDEC)
  • Phosphodiesterase 1
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 1A (PDE1A)
  • Phosphodiesterase 2 and 5 (PDE2 and PDE5)
  • Phosphodiesterase 2A
  • Phosphodiesterase 3
  • Phosphodiesterase 3 (PDE3)
  • Phosphodiesterase 4
  • Phosphodiesterase 4 and 5 (PDE4 and PDE5)
  • Phosphodiesterase 5A
  • Phosphodiesterase 6
  • Phosphodiesterase 6C
  • Phosphodiesterase 6C (PDE6C)
  • Phosphodiesterase 7
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 10 (PDE10A)
  • Phosphodiesterase Type 11 (PDE11A)
  • Phosphodiesterase Type 2 (PDE2A)
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 4 (PDE4B)
  • Phosphodiesterase Type 4 (PDE4D)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 5 (PDE5A) Mutant (661-681 deletion)
  • Phosphodiesterase Type 5 (PDE5A) Mutant (663-678 deletion)
  • Phosphodiesterase Type 6 (PDE6)
  • Phosphodiesterase Type 7 (PDE7B)
  • Phosphodiesterase Type 9 (PDE9A)
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated potassium channel subunit Kv4.3
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
  • cGMP-dependent 3',5'-cyclic phosphodiesterase
  • cGMP-specific 3',5'-cyclic phosphodiesterase
  • 5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
  • 5-{2-ethoxy-5-[(4-methylpiperazine-1-)sulfonyl]phenyl}-1-methyl-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-7-one
  • CHEMBL192
  • SILDENAFIL CITRATE
  • Sildenafil
  • Sildenafil#
  • Viagra
39 Ki 104 IC50 1 Kd 8 EC50
  • Androgen Receptor
  • Cytochrome P450 3A
  • Estrogen receptor
  • Glucocorticoid
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • P-glycoprotein (P-gp)
  • Progesterone receptor
  • Thyroid Hormone Receptor (TR-beta)
  • Thyroid hormone receptor
  • (10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]-14-hydroxy-15-methyl-14-(prop-1-yn-1-yl)tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6-dien-5-one
  • Mifeprex
  • Mifepristone
  • RU-486
  • RU486 (tetramethyl-rhodamine conjugated)
100 Ki 52 IC50
  • 5-Hydroxytryptamine receptor 6 (5-HT6)
  • 5-Hydroxytryptamine receptor 7 (5-HT7)
  • 5-hydroxytryptamine receptor 1A (5-HT1A)
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • ADENOSINE A2
  • ADRA2B
  • ADRB2
  • Adenosine receptor A1
  • Adenosine transporter
  • Adenylate cyclase Forskolin
  • Adrenergic receptor beta
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Calcium channel
  • Calcium channel (Type L)
  • Cholecystokinin receptor
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • D(2) dopamine receptor
  • DOPAMINE
  • Dopamine Transporter (DAT)
  • Ecto-5'-nucleotidase (e5'NT)
  • GABA A
  • GRIA3
  • Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1)
  • Glutamate kainate
  • Glycine, non-strychnine
  • HTR4
  • Histamine H1 receptor
  • Histamine H2 receptor
  • Histamine H3 receptor
  • Histamine receptor (H3)
  • Inositol Triphosphate
  • Ionotropic glutamate receptor NMDA 1/2D
  • Kappa-type opioid receptor
  • Monoamine Oxidase Type B (MAO-B)
  • Monoamine oxidase
  • Monoamine transporters; serotonin & dopamine
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Neurokinin 1 receptor
  • Neurokinin 3 receptor
  • Neuropeptide Y receptor type 1
  • Nicotinic Alpha-Bungarotoxin
  • Nitric-oxide synthase, brain
  • Nociceptin/mu opioid receptor
  • Norepinephrine transporter
  • Opioid receptors; mu & delta
  • Potassium Channel (Ca2+ dependent)
  • Potassium voltage-gated channel subfamily H member 2
  • Protein kinase C
  • Renal Outer Medullary Potassium (ROMK)
  • SOMATOSTATIN
  • Serotonin (5-HT) receptor
  • Serotonin receptor (2b and 2c)
  • Sigma non-opioid intracellular receptor 1
  • Sodium (Site 1)
  • Sodium (Site 2)
  • Sodium channel protein type 5 subunit alpha
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • TACR2
  • Transporter
  • Voltage-dependent N-type calcium channel subunit alpha-1B
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated potassium channel subunit Kv4.3
  • CAS_136434-34-9
  • DULOXETINE
  • LY-248686
  • LY248686