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Compound Name:

Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
15 Ki 7 IC50
0 ΔG°
  • ADORA3
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor A1
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • Thymidine Kinase
  • Thymidine kinase
  • Thymidine kinase, cytosolic
  • Thymidylate kinase
  • dT
  • thymidine
3 Ki 22 IC50
0 ΔG°
  • Caspase-1
  • Caspase-3
  • Caspase-7
  • Caspase-8
  • (4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}-2-methylpropyl]carbamoyl}-4-[(3S)-3-acetamido-3-formamidopropanoic acid]butanoic acid
  • Ac-DEVD-CHO
  • CHEMBL417149
10 Ki 16 IC50
  • Acetylcholinesterase
  • Cholinesterases
  • 1,5-bis(4-allyldimethylammoniumphenyl)-pentan-3-one dibromide
  • 4-(5-{4-[dimethyl(prop-2-en-1-yl)aminiumyl]phenyl}-3-oxopentyl)-N,N-dimethyl-N-(prop-2-en-1-yl)anilinium dibromide
  • BW284c51
  • CHEMBL140020
  • CHEMBL464538
14 Ki 2 IC50 10 Kd
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase I
  • LDL-associated phospholipase A2
  • CHEMBL27601
  • benzenesulfonamide
  • hCA inhibitor, 6
8 Ki 18 IC50
  • Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2)
  • Myosin light chain kinase, smooth muscle
  • Polo-Like Kinase 3
  • Polo-Like Kinase 4
  • Rho-associated protein kinase 1
  • Rho-associated protein kinase 2
  • Rho-kinase (ROCK II)
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK2
  • cAMP-Dependent Protein Kinase (PKA)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (E127D)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (L49I)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/Q181K/T183A)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/V123M/E127D/Q181K/T183A)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/V123M/Q181K/T183A)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (Q181K/T183A)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (T183A)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (V123M)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (V123M/Q181K/T183A)
  • cAMP-Dependent Protein Kinase (PKA) Mutant (V123M/T183A)
  • (S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE
  • 4-methyl-5-{[(2S)-2-methyl-1,4-diazepane-1-]sulfonyl}isoquinoline
  • H-1152
  • H-1152P
2 Ki 24 IC50
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Hepatocyte nuclear factor 4-alpha
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 5
  • Phosphodiesterase 6
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 10 (PDE10A)
  • Phosphodiesterase Type 11 (PDE11A)
  • Phosphodiesterase Type 2 (PDE2A)
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 4 (PDE4B)
  • Phosphodiesterase Type 4 (PDE4D)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 7 (PDE7B)
  • Phosphodiesterase Type 9 (PDE9A)
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cGMP-specific 3',5'-cyclic phosphodiesterase
  • perilipin-1
  • perilipin-5
  • 2-{2-ethoxy-5-[(4-ethylpiperazine-1-)sulfonyl]phenyl}-5-methyl-7-propyl-3H,4H-imidazo[1,5-a][1,2,4]triazin-4-one
  • CHEMBL1520
  • VARDENAFIL
  • Vardenafil
  • citric acid;2-[2-ethoxy-5-(4-ethylpiperazino)sulfonyl-phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one
  • vardenafil
26 Ki
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US9062078, 10A
  • US9062078, 10B
  • US9062078, 9
  • US9475819, 9
  • US9637496, 10B
  • US9695183, 10B
4 Ki 16 IC50 6 EC50
  • ATP-binding cassette sub-family G member 2
  • Aldehyde oxidase
  • Androgen receptor
  • Baculoviral IAP repeat-containing protein 2/Estrogen receptor
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Estradiol receptor beta (ERβ)
  • Estrogen receptor
  • Estrogen-Related Receptor, gamma
  • Nuclear receptor subfamily 1 group I member 2
  • Sarcoplasmic/endoplasmic reticulum calcium ATP-ase
  • UDP-glucose 4-epimerase
  • 4-[(3E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
  • 4-[(E)-4-(4-hydroxyphenyl)hex-3-en-3-yl]phenol
  • CHEMBL411
  • Diethylstilbestrol
  • Diethylstilbestrol (1)
  • Stilbestrol
  • Stilboestroform
24 IC50 2 EC50
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Gag-Pol polyprotein
  • Human immunodeficiency virus type 1 reverse transcriptase
  • Reverse Transcriptase
  • Reverse transcriptase
  • Rilpivirine
26 IC50
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase JAK2
  • US10106559, Example 12
  • US10435415, Example 12
  • US9334290, 11
  • US9850258, Example 12
6 Ki 3 IC50 17 Kd
  • ADRB2
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • Beta-adrenergic receptor
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Serotonin 1B/1D receptor
  • CHEMBL6995
  • N-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
  • Practolol
  • Practolol,(+)
  • Practolol,(-)
26 Ki
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • CHEMBL1644696
  • CNO(-1)
  • cyanate
20 Ki 1 IC50 5 EC50
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • HTR4
  • Serotonin (5-HT) receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
  • Serotonin 4 (5-HT4) receptor
  • 2-Piperidinoethyl 4-amino-5-chloro-2-methoxybenzoate
  • CHEMBL286136
  • ML 10302
  • ML10302
5 Ki 21 IC50
  • Myosin light chain kinase, smooth muscle
  • NAD-dependent deacetylase sirtuin 2
  • PKC alpha and beta-2
  • Polo-Like Kinase 3
  • Polo-Like Kinase 4
  • Protein Kinase C
  • Protein kinase C (PKC)
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • Protein kinase C, gamma
  • Serine/threonine-protein kinase D1
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK2
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-Specific Protein Kinase
  • Tyrosine-protein kinase BLK
  • cAMP-Dependent Protein Kinase (PKA)
  • cGMP-Dependent Protein Kinase
  • 3-{23-methyl-14-oxo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17,19,21-nonaen-3-yl}propanenitrile
  • CHEMBL302449
  • Go 6976
  • Indolocarbazole deriv.
5 Ki 18 IC50 3 Kd
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Myelin transcription factor 1
  • PDGFR-beta/Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Serine/threonine-protein kinase WEE1
  • Tyrosine- and threonine-specific cdc2-inhibitory kinase
  • Wee1-like protein kinase 2
  • 2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv.
  • 6-(2,6-Dichlorophenyl)-2-[4-(2-diethylaminoethoxy)phenylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one, Dihydrochloride
  • 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • CHEMBL49120
  • PD166285
1 Ki 23 IC50 2 EC50
  • 3',5'-cyclic phosphodiesterase
  • Bile salt export pump
  • Botulinum neurotoxin type A
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonic anhydrase 15
  • Heat shock protein HSP 90-alpha
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Kappa-type opioid receptor
  • LAP4
  • MEP2
  • Multidrug resistance-associated protein 4
  • CLIOQUINOL
  • Clioquinol (CQ)
  • TG2-36-2
  • cid_2788
5 Ki 2 IC50 19 EC50
  • Apoptosis regulator Bcl-2
  • Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH).
  • BCL-W
  • Bcl-2-related protein A1
  • Estradiol receptor beta (ERβ)
  • G protein signalling regulator 19
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Isoform Bcl-X(L)
  • POsterior Segregation family member (pos-1)
  • RGS7
  • RecName: Full=Zinc finger protein mex-5
  • Regulator of G-protein signaling 8
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • glutathione S-transferase
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
  • 2,5-bis(chloranyl)-3-(4-methylpiperazin-1-yl)-6-(2-piperidin-1-yl-1,3-thiazol-5-yl)cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-(4-methyl-1-piperazinyl)-6-[2-(1-piperidinyl)-1,3-thiazol-5-yl]benzo-1,4-quinone
  • 2,5-dichloro-3-(4-methyl-1-piperazinyl)-6-[2-(1-piperidinyl)-5-thiazolyl]cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-(4-methylpiperazin-1-yl)-6-(2-piperidin-1-yl-1,3-thiazol-5-yl)cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-(4-methylpiperazino)-6-(2-piperidinothiazol-5-yl)-p-benzoquinone
  • MLS000548207
  • SMR000115103
  • cid_1002249
3 Ki 7 IC50 16 EC50
  • Angiotensin II receptor
  • Apelin receptor
  • Apoptosis regulator Bcl-2
  • BCL-W
  • BZLF2
  • Bcl-2-like protein 11
  • Bcl-2-related protein A1
  • G protein signalling regulator 19
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • RGS7
  • Regulator of G-protein signaling 8
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
  • streptokinase A precursor
  • 3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl acetate
  • 3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl ethanoate
  • MLS000521052
  • SMR000131461
  • acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl ester
  • acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-benzofurazan-5-yl]amino]propyl ester
  • cid_11957209
20 IC50 6 EC50
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • G protein signalling regulator 19
  • Gag-Pol polyprotein
  • M18 aspartyl aminopeptidase
  • MPI protein
  • Mannose-6-phosphate isomerase
  • Procathepsin L
  • RGS7
  • Regulator of G-protein signaling 8
  • diphosphomevalonate decarboxylase
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • insulin-degrading enzyme isoform 1 precursor
  • large T antigen
  • mevalonate kinase
  • neutrophil cytosolic factor 1
  • phosphatase, orphan 1
  • phosphomannomutase 2
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
  • 2-(4-methyl-3-piperidin-1-ylsulfonyl-phenyl)-1,2-benzothiazol-3-one
  • 2-(4-methyl-3-piperidin-1-ylsulfonylphenyl)-1,2-benzothiazol-3-one
  • 2-(4-methyl-3-piperidinosulfonyl-phenyl)-1,2-benzothiazol-3-one
  • 2-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-1,2-benzothiazol-3-one
  • MLS000057572
  • SMR000060796
  • cid_2327953
26 IC50
  • 1,3-beta-glucan synthase component GLS2
  • 3-phosphoinositide dependent protein kinase-1
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cytochrome P450 4B1
  • DNA-PK/Ku70/Ku85
  • Dual specificity protein kinase TTK
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphoinositide 3-Kinase (PI3K), delta
  • Serine-protein kinase ATM
  • Serine/threonine-protein kinase ATR
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • p110α/p85α
  • p110β/p85α
  • 7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one
  • US10407446, Example 3
2 Ki 23 IC50 1 Kd
  • Alpha-chymotrypsin
  • Beta-lactamase AmpC
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Complement C5
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • EBifunctional epoxide hydrolase 2
  • Epoxide hydratase
  • Epoxide hydrolase 2
  • Malate dehydrogenase cytoplasmic
  • Multidrug resistance-associated protein 4
  • Prostaglandin E synthase/G/H synthase 2
  • 3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid
  • CHEMBL1071
  • Daypro
  • OXAPROZIN
  • WY-21743
  • oxaprosin
5 Ki 20 IC50 1 Kd
  • Arachidonate 5-lipoxygenase
  • Carbonic anhydrase
  • Carbonic anhydrase 2
  • Carbonic anhydrases; II & IX
  • Cereblon/Histone deacetylase 6
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Indoleamine 2,3-dioxygenase
  • Mandelate racemase (MR)
  • PA/PB1
  • Stromelysin-1
  • BENZHYDROXAMIC ACID
  • BENZOHYDROXAMATE
  • CHEMBL16300
  • N-Hydroxy-benzamide
  • N-hydroxybenzamide
  • benzoyl hydroxamic acid
22 Ki 4 IC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • OPRD1
  • Opioid receptors; mu & delta
  • 2-{2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-3-hydroxy-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-hydroxy-butyric acid
  • CHEMBL124283
  • DSLET
  • DSLET-OH
  • Tyr-D-Ser-Gly-Phe-Leu-Thr
26 Ki
  • SSTR1
  • SSTR2
  • SSTR3
  • SSTR4
  • SSTR5
  • Somatostatin receptor type 1
  • Somatostatin receptor type 2
  • Somatostatin receptor type 3
  • Somatostatin receptor type 4
  • Somatostatin receptor type 5
  • Ala-Gly-c(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys)-OH
  • Ala-Gly-c-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys](SRIF-14)
  • CHEMBL411836
  • H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: 3-14)
  • H-Ala-Gly-c[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]-OH
  • SOMATOSTATIN
  • SRIF-14
  • SRIF14
  • Somatostatin receptor ligand
  • Somatostatin-14
  • somatostatin(H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH)
18 Ki 4 IC50 4 EC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • (-)-5-hydroxy-2-(dipropylamino)tetralin
  • (-)-6-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
  • 5-hydroxy-2-(dipropylamino)tetralin
  • 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol
  • 6-Dipropylamino-5,6,7,8-tetrahydro-naphthalen-1-ol (DP-5-ADTN)
  • CHEMBL273273
20 Ki 6 IC50
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Bile salt export pump
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Norepinephrine Monoamine transporters
  • Norepinephrine transporter
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • CHEMBL37744
  • ZIMELIDINE
  • Zimeldine
  • [3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine
  • [3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine (Zimelidine)
  • [3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine(Zimeldine)
  • cis -[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine;HCl
  • trans-[3-(4-Bromo-phenyl)-3-pyridin-3-yl-allyl]-dimethyl-amine;C2H4O4
17 Ki 9 IC50
  • Acetylcholinesterase
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Choline Acetyltransferase
  • Choline acetylase
  • Choline transporter
  • Creatine transporter
  • Neuronal acetylcholine receptor
  • Neuronal acetylcholine receptor Alpha-3/Beta-2
  • Neuronal acetylcholine receptor Alpha-3/Beta-4
  • Neuronal acetylcholine receptor protein alpha-2/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit
  • Neuronal acetylcholine receptor subunit alpha-2
  • Neuronal acetylcholine receptor subunit alpha-3
  • Neuronal acetylcholine receptor subunit alpha-4
  • Solute carrier family 22 member 1
  • Solute carrier family 22 member 2
  • n-AChR
  • 2-hydroxy-N,N,N-trimethylethanaminium
  • CHEMBL282468
  • CHEMBL293410
  • CHEMBL920
  • N-trimethylethanolamine
  • OXTRIPHYLLINE
  • choline
  • trimethylethanolamine
10 Ki 14 IC50 2 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Opioid receptor
  • Opioid receptors; mu/kappa/delta
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • Solute carrier family 22 member 1
  • 1-Methyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester
  • 1-Methyl-4-phenyl-piperidine-4-carboxylic acid ethyl ester(Meperidine)
  • 4-Ethoxycarbonyl-1-methyl-4-phenyl-piperidinium
  • CHEMBL607
  • Demerol
  • MEPERIDINE
  • MEPERIDINE HYDROCHLORIDE
  • Mepergan
  • Pethidine
  • ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
26 Ki
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2C
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • D(2) dopamine receptor
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Norepinephrine transporter
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • 4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine, HCl
  • CHEMBL40733
  • Desmethylsertraline
6 Ki 6 Kd 14 EC50
  • Retinoic acid receptor RXR-alpha
  • Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta
  • Retinoic acid receptor RXR-alpha/gamma
  • Retinoid X receptor beta
  • Retinoid X receptor gamma
  • Retinoid X receptor gamma/retinoic acid receptor alpha
  • Retinoid receptor
  • 4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid
  • CHEMBL96184
18 Ki 7 IC50 1 EC50
  • Coagulation factor X
  • Coagulation factor X/antithrombin III
  • Hepsin
  • Plasminogen
  • Prothrombin
  • Thrombin
  • Trypsin
  • Trypsin II
  • Trypsin-1
  • 1-[N-(naphthalen-2-ylsulfonyl)glycyl-4-carbamimidoyl-D-phenylalanyl]piperidine
  • CHEMBL51173
  • N-[(R)-1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide
  • N-[1-(4-Carbamimidoyl-benzyl)-2-(3,4-dihydro-2H-pyridin-1-yl)-2-oxo-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide
  • N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide
  • N-[1-(4-Carbamimidoyl-benzyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide(NAPAP)
12 Ki 12 IC50 2 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Opioid receptors; mu & delta
  • 4-((R)-((2S,5R)-4-allyl-2,5-dimethylpiperazin-1-yl)(3-hydroxyphenyl)methyl)-N,N-diethylbenzamide
  • 4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-hydroxy-phenyl)-methyl]-N,N-diethyl-benzamide
  • 4-[(4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-hydroxy-phenyl)-methyl]-N,N-diethyl-benzamide(SNC-86)
  • 4-[(R)-((2S,5R)-4-Allyl-2,5-dimethyl-piperazin-1-yl)-(3-hydroxy-phenyl)-methyl]-N,N-diethyl-benzamide
  • BW-373U86
  • CHEMBL25230
  • SNC-86
25 IC50 1 Kd
  • Bromodomain testis-specific protein
  • Bromodomain-containing protein 4
  • Casein kinase I isoform delta
  • Casein kinase I isoform epsilon
  • MAP kinase p38
  • Mitogen-activated protein kinase 11
  • Mitogen-activated protein kinase 14
  • Tau-tubulin kinase 1
  • Tau-tubulin kinase 2
  • Tyrosinase
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • p38 MAP kinase alpha/beta
  • CHEBI:79090
  • SB-202190
  • US10865384, Compound SB202190
26 IC50
  • Axin-1/Glycogen synthase kinase-3 beta
  • CaM kinase IV
  • Casein kinase I isoform delta
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 1
  • Protein kinase C alpha type
  • RAC-alpha serine/threonine-protein kinase
  • Rho-associated protein kinase 2
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase MST2
  • Serine/threonine-protein kinase Nek2
  • Serine/threonine-protein kinase PLK3
  • Testis-specific serine/threonine-protein kinase 2
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • CHEMBL3314140
26 IC50
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Mast/stem cell growth factor receptor Kit
  • NT-3 growth factor receptor
  • NUAK family SNF1-like kinase 1
  • Salt-inducible kinase 2 (SIK2)
  • Serine/threonine-protein kinase 2
  • Serine/threonine-protein kinase SIK2
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • CHEMBL3326006
22 Ki 4 EC50
  • 5-hydroxytryptamine receptor 3A
  • D(2) dopamine receptor
  • HTR4
  • Serotonin (5-HT) receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
  • Serotonin 4 (5-HT4) receptor
  • 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-((S)-methoxy)-benzamide
  • 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide
  • 4-Amino-N-(S)-1-aza-bicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxy-benzamide
  • CHEMBL28992
  • ZACOPRIDE,R
26 Ki
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine D1B
  • Dopamine receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
  • 3-[4-(4-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine
  • CHEMBL28607
26 Ki
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • DRD1
  • CHEMBL163087
  • Dipropyl-(4-trimethylsilanylethynyl-cyclohex-3-enyl)-amine
18 Ki 4 IC50 4 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide
  • 8-CAC
  • 8-carboxamidocyclazocine
  • CHEMBL58646
  • US9656961, Example 00157
26 Ki
  • PKC alpha and beta-2
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • Protein kinase C theta type
  • Protein kinase C, PKC; classical/novel
  • Protein kinase C, epsilon
  • Protein kinase C, eta
  • Protein kinase C, gamma
  • (2S,5S)-8-Decyl-5-hydroxymethyl-2-isopropyl-1-methyl-1,2,5,6-tetrahydro-benzo[e][1,4]oxazocin-3-one
  • 8-Decyl-5-hydroxymethyl-2-isopropyl-1-methyl-1,2,5,6-tetrahydro-benzo[e][1,4]oxazocin-3-one
  • CHEMBL318971
26 Ki
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Serotonin (5-HT) receptor
  • 3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
  • 3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide
  • 3,N-Dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl)-propyl]-benzenesulfonamide (SB-258719)
  • 4-Methyl-1-[(R)-3-methyl-4-(toluene-3-sulfonyl)-pentyl]-piperidine
  • CHEMBL12264
  • SB-258719
25 Ki 1 EC50
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A2a and A3
  • Adenosine receptor A2b
  • Adenosine receptor A3
  • G protein-coupled receptor 80
  • (2S,3S,4R,5R)-5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (2-amino-ethyl)-amide
  • (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-(2-aminoethyl)-3,4-dihydroxy-tetrahydrofuran-2-carboxamide
  • 5'-N-[(2-AMINO)ETHYL CARBOXAMIDO] ADENOSINE
  • 5-(6-Amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-carboxylic acid (2-amino-ethyl)-amide
  • Adenosine analog, 1
  • CHEMBL129903
18 Ki 8 EC50
  • GRIA3
  • Glutamate receptor 1
  • Glutamate receptor ionotropic, AMPA
  • Glutamate receptor ionotropic, AMPA 2
  • Glutamate receptor ionotropic, AMPA 4
  • Glutamate receptor ionotropic, kainate
  • Glutamate receptor ionotropic, kainate 1
  • Ionotropic glutamate receptor kainate 2/5
  • (S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cyclopenta[d]-pyrimidin-2,4(1H,3H)dione
  • (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID
  • 2-Amino-3-(2,4-dioxo-2,3,4,5,6,7-hexahydro-cyclopentapyrimidin-1-yl)-propionic acid
  • CHEMBL337577
14 Ki 12 IC50
  • 5-hydroxytryptamine receptor 1A (5HT1A)
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 3A
  • Alpha-2A adrenergic receptor
  • D(2) dopamine receptor
  • Dopamine D1 receptor
  • Glycine receptor alpha-4 chain
  • Histamine H1 receptor
  • NMDA receptor subunit 2C (GluN2C)
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neuromedin-K receptor
  • Sigma non-opioid intracellular receptor 1
  • Sigma-1 receptor
  • 1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]
  • 1'-benzyl-3-methoxyspiro[isochroman-1,4'-piperidine]
  • CHEMBL141209
8 Ki 9 IC50 9 EC50
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • G protein-coupled receptor 44
  • GTP-binding protein (rab7)
  • Peroxisome proliferator-activated receptor
  • Presenilin-1
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Ras-related C3 botulinum toxin substrate 1
  • Ras-related protein Rab-2A.
  • cell division cycle 42 (GTP binding protein, 25kDa)
  • ras protein
  • (Z)-2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid
  • 2-(3-(4-(methylthio)benzylidene)-6-fluoro-2-methyl-3H-inden-1-yl)acetic acid
  • CHEMBL18797
  • SULINDAC SULFIDE
  • Sulindac sulphide
  • [6-Fluoro-2-methyl-3-(4-methylsulfanyl-benzylidene)-3H-inden-1-yl]-acetic acid
  • cid_5352624
  • {6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-meth-(E)-ylidene]-3H-inden-1-yl}-acetic acid
  • {6-Fluoro-2-methyl-3-[1-[4-(methyl-lambda*4*-sulfanyl)-phenyl]-meth-(E)-ylidene]-3H-inden-1-yl}-acetic acid
13 Ki 13 IC50
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Melanin-concentrating hormone receptor 2/HERG
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • Neuromedin-K receptor (NK-3 receptor)
  • Potassium voltage-gated channel subfamily H member 2
  • hnk-3
  • CHEMBL3608687
  • US10030025, Compound 3
  • US10836768, Cpd no 3
  • US9422299, 3
  • US9987274, Compound 3
4 Ki 21 IC50 1 EC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cyclooxygenase
  • Cytochrome P450 1A
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • DNA Gyrase
  • Monoamine Oxidase Type B (MAO-B)
  • Multidrug resistance-associated protein 4
  • Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • Voltage-gated L-type calcium channel
  • streptokinase A precursor
  • (Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • (R)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
  • (S)-3-(3-Fluoro-4-morpholin-4-yl-phenyl)-5-[(1-hydroxy-ethylamino)-methyl]-oxazolidin-2-one
  • (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
  • (S)-N-((3-fluoro-4-morpholinophenyl)-2-oxaoxazolidin-5-yl)methyl)acetamide
  • Benzotriazol-2-yl-acetonitrile
  • CHEMBL126
  • LINEZOLID
  • Linezoid
  • N-((S)-2-oxo-3-(S)-2,3,3a,4-tetrahydro-1H-benzo[b]pyrrolo[1,2-d][1,4]oxazin-7-yl-oxazolidin-5-ylmethyl)-acetamide
  • N-[(R)-3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • N-[(S)-3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide(linezolid)
  • N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
  • U-100766
  • Zyvox
  • cid_441401
23 Ki 3 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Opioid receptors; mu & delta
  • Potassium voltage-gated channel subfamily H member 2
  • (3R)-7-Hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
  • (3R)-7-hydroxy-N-(1S)-1-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl-2-methylpropyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
  • (3R)-7-hydroxy-N-[(1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide
  • (R)-7-hydroxy-N-((S)-1-((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)-3-methylbutan-2-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
  • 7-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {(S)-1-[(3R,4R)-4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-amide
  • 7-Hydroxy-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid {1-[4-(3-hydroxy-phenyl)-3,4-dimethyl-piperidin-1-ylmethyl]-2-methyl-propyl}-amide
  • CHEMBL415247
  • atrans-(3R,4R)-dimethyl-4-(3-hydroxyphenyl) piperidine
26 Ki
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Norepinephrine Monoamine transporters
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • (3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • CHEMBL92860
25 IC50 1 EC50
  • Somatostatin receptor type 1
  • Somatostatin receptor type 2
  • Somatostatin receptor type 3
  • Somatostatin receptor type 4
  • Somatostatin receptor type 5
  • (4R,7S,10S,13S,16R,19S,22S,25R)-16-((1H-indol-3-yl)methyl)-25-amino-13-(4-aminobutyl)-7,19,22-tribenzyl-10-((R)-1-hydroxyethyl)-6,9,12,15,18,21,24-heptaoxo-1,2-dithia-5,8,11,14,17,20,23-heptaazacyclohexacosane-4-carboxylic acid
  • (S)-25-Amino-13-(4-amino-butyl)-7,19,22-tribenzyl-10-((R)-1-hydroxy-ethyl)-16-(1H-indol-3-ylmethyl)-6,12,15,18-tetra(S)-oxo-9,21-di(R)-oxo-24-oxo-1,2-dithia-5,8,11,14,17,20,23-heptaaza-cyclohexacosane-4-carboxylic acid
  • CHEMBL266477
  • H-c(Cys3-Phe6-Phe7-DTrp8-Lys9-Thr10-Phe11-Cys14)-OH
  • ODT-8
4 Ki 1 IC50 21 EC50
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • D(2) dopamine receptor
  • FXN frataxin
  • ARFORMOTEROL TARTRATE
  • CHEMBL1363
  • CHEMBL605993
  • FORMOTEROL
  • FORMOTEROL FUMARATE
  • Foradil
  • N-(2-Hydroxy-5-{1-hydroxy-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide
  • N-(2-hydroxy-5-((R)-1-hydroxy-2-((R)-1-(4-methoxyphenyl)propan-2-ylamino)ethyl)phenyl)formamide
  • Symbicort
  • cid_9912089
8 Ki 18 IC50
  • 3-oxoacyl-acyl-carrier protein reductase
  • 6-phosphogluconate dehydrogenase (6PGD)
  • Apoptosis regulator Bcl-2/Bcl-2 homologous antagonist/killer
  • Cannabinoid receptor 1
  • Cannabinoid receptor 2
  • Death-associated protein kinase 1
  • ELAV-like protein 3
  • Enoyl-ACP Reductase (FabI)
  • Enoyl-acyl-carrier protein reductase
  • Fatty acid synthase
  • Genome polyprotein
  • Glucose-6-phosphate 1-dehydrogenase
  • Hepatocyte growth factor receptor
  • Human immunodeficiency virus type 1 reverse transcriptase
  • Mitogen-activated protein kinase 14
  • Proteasome subunit beta type-1/beta type-5
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • (-)-Epicatechin-3-gallate
  • (-)-epicatechin 3-O-gallate
  • (-)-epicatechin gallate
  • (-)-epicatechingallate
  • (-)epicatechingallate
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-3-yl 3,4,5-trihydroxybenzoate
  • 3,4,5-Trihydroxy-benzoic acid (2R,3R)-2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester
  • 3,4,5-Trihydroxy-benzoic acid 2-(3,4-dihydroxy-phenyl)-5,7-dihydroxy-chroman-3-yl ester
  • CHEMBL36327
  • Epicatechin gallate
  • Epicatechin-3-O-gallate
15 Ki 11 IC50
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)
  • Lethal(3)malignant brain tumor-like protein 4
  • MBT domain-containing protein 1 (MBTD1)
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Voltage-dependent L-type calcium channel subunit alpha-1C
  • 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
  • 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
  • 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
  • 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
  • Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
  • CHEMBL1231
  • Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
  • OXYBUTYNIN CHLORIDE
3 Ki 15 IC50 8 EC50
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • Acid-sensing ion channel 1
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto reductase family 1 member C4 (AK1C4)
  • Amiloride-sensitive cation channel 3
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • GTP-binding protein (rab7)
  • Interleukin-8 receptors, CXCR1/CXCR2
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Ras-related C3 botulinum toxin substrate 1
  • Ras-related protein Rab-2A.
  • cell division cycle 42 (GTP binding protein, 25kDa)
  • ras protein
  • (S)-2-(4-Isobutyl-phenyl)-propionic acid
  • (S)-2-(4-isobutylphenyl)propanoic acid
  • (S)-ibuprofen
  • CHEMBL175
  • DEXIBUPROFEN
  • IBUPROFEN LYSINE
14 Ki 10 IC50 2 Kd
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Adrenergic Alpha
  • Androgen receptor
  • Anti-estrogen binding site (AEBS)
  • C-8 sterol isomerase
  • Corticosteroid-binding globulin
  • Mineralocorticoid receptor
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • Sigma non-opioid intracellular receptor 1
  • Solute carrier family 22 member 1
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Solute carrier organic anion transporter family member 1A1
  • Testis-specific androgen-binding protein
  • (11beta)-11,21-dihydroxypregn-4-ene-3,20-dione
  • 11beta,21-dihydroxypregn-4-ene-3,20-dione
  • 11beta,21-dihydroxyprogesterone
  • 17-deoxycortisol
  • CHEMBL110739
  • corticosterone
18 Ki 3 IC50 5 EC50
  • Ecdysone receptor
  • P-glycoprotein 1
  • Protein ultraspiracle
  • Ultraspiracle
  • Ultraspiracle isoform-A
  • CHEBI:38452
  • TEBUFENOZIDE
  • Tebufenozide
17 IC50 9 EC50
  • Endoplasmin
  • Heat Shock Protein 90 (Hsp90)
  • Heat shock protein 75 kDa, mitochondrial
  • Heat shock protein 90 beta
  • Heat shock protein HSP 90-alpha
  • Heat shock protein HSP 90-beta
  • Hsp90 co-chaperone
  • Receptor tyrosine-protein kinase erbB-2
  • 8-(6-iodo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)adenine
  • 8-(6-iodobenzo[d][1,3]dioxol-5-ylthio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
  • 8-[(6-IODO-1,3-BENZODIOXOL-5-YL)THIO]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE
  • CHEMBL200102
  • US10336757, Compound PU-H71
  • US10676476, Example 9
2 Ki 22 IC50 2 EC50
  • Cannabinoid receptor 1
  • Cannabinoid receptor 2
  • Cytochrome P450 1A
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Potassium voltage-gated channel subfamily H member 2
  • CHEMBL220360
  • MK-0364
  • MK-0634
  • N-((2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl)-2-methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanamide
  • N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide
  • TARANABANT
  • Taranbant
23 Ki 3 IC50
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A2a and A3
  • Adenosine receptor A2b
  • Adenosine receptor A3
  • Adenosine receptors; A2a & A2b
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2D6 (2D6)
  • 2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]-piperazin-1-yl}-ethyl)-2,7-dihydro-3H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
  • 2-furan-2-yl-7-(2-{4-[4-(2-methoxy-ethoxy)-phenyl]-piperazin-1-yl}-ethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine
  • 7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
  • CHEMBL240624
  • SCH-420814
  • preladenant
11 Ki 11 IC50 4 Kd
  • Adrenaline alpha1
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • HIV-1 protease
  • Human immunodeficiency virus type 1 protease
  • Multidrug resistance-associated protein 4
  • Protease
  • Voltage-gated L-type calcium channel
  • CHEBI:63621
  • Fortovase
  • Invirase
  • Ro-31-8959
  • Ro-318959000
  • SAQUINAVIR
  • Saquinavir
  • US10806794, Compound Saquinavir
4 Ki 21 IC50 1 Kd
  • 12-Lipoxygenase (12-LOX)
  • 3',5'-cyclic phosphodiesterase
  • 7,8-dihydro-8-oxoguanine triphosphatase
  • Arachidonate 15-lipoxygenase
  • Cytochrome P450 19A1
  • Fatty acid synthase
  • Isocitrate dehydrogenase [NADP] cytoplasmic
  • MAP/microtubule affinity-regulating kinase 4
  • Neutral sphingomyelinase
  • Nuclear factor NF-kappa-B
  • Nuclear factor NF-kappa-B (NF-kB)
  • Probable maltase-glucoamylase 2
  • Protein-tyrosine phosphatase 1B
  • Sialidase
  • Sphingomyelin phosphodiesterase
  • Stimulator of interferon genes protein
  • beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ)
  • beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ)
  • 1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2-enyl)-xanthen-9-one
  • 1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one
  • 1,3,6-trihydroxy-7-methoxy-2,8-diprenylxanthone
  • CHEMBL323197
  • Mangostin
  • alpha-mangostin
2 Ki 20 IC50 3 Kd 1 EC50
  • BRS3
  • Cytochrome P450 2C9
  • Cytochrome P450 3A
  • Cytochrome P450 monooxygenase BM3 (BM3 A82F)
  • Cytochrome P450 monooxygenase BM3 (BM3 DM)
  • Cytochrome P450 monooxygenase BM3 (BM3 F87V)
  • Fatty acid synthase
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • P-glycoprotein 1
  • Potassium-transporting ATPase
  • Potassium-transporting ATPase alpha chain 1/beta chain
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A4
  • Uridine-5'-diphosphoglucuronosyltransferase 1A6
  • Uridine-5'-diphosphoglucuronosyltransferase 2B10
  • Uridine-5'-diphosphoglucuronosyltransferase 2B7
  • (RS)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl) methylsulfinyl)-1H-benzo[d]imidazole
  • (omeprazole)5-Methoxy-2-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethanesulfinyl)-1H-benzoimidazole
  • 2-(3-methoxy-2,4-dimethylbenzylsulfinyl)-6-methoxy-1H-benzo[d]imidazole
  • 5-Methoxy-2-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethanesulfinyl)-1H-benzoimidazole
  • 5-Methoxy-2-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethanesulfinyl)-1H-benzoimidazole (omeprazole)
  • 5-Methoxy-2-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethanesulfinyl)-1H-benzoimidazole(omeprazole)
  • 5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole
  • 5-methoxy-2-(2-(4-methoxy-3,5-dimethylpyridin-2-yl)ethylsulfinyl)-1H-benzo[d]imidazole
  • 6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]imidazole
  • CHEMBL1503
  • ESOMEPRAZOLE SODIUM
  • H-168/68
  • OMEPRAZOLE
  • Omeprazole (OMP)
  • Prilosec
  • cid_4594
26 IC50
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2A6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Melanin-concentrating hormone receptor 2/HERG
  • Metabotropic glutamate receptor 5
  • CHEMBL4098822
26 Ki
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-3 adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Histamine H3 receptor
  • Mu-type opioid receptor
  • Serotonin (5-HT) receptor
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • 4-(3-(2-Fluoroethoxy)-2-methoxy-benzoyl)-1-(2-p-fluorophenylethyl)-piperidine
  • CHEMBL516088
26 IC50
  • Amine oxidase (flavin-containing) A
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
  • Alternariol 5-O-Methyl Ether
  • CHEMBL483526
26 IC50
  • Angiopoietin-1 receptor
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent-like kinase 5
  • Ephrin type-A receptor 2
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 4
  • Insulin receptor
  • PKC alpha and beta-2
  • Platelet-derived growth factor receptor beta
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
  • 1-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
  • CHEMBL1081198
5 Ki 21 IC50
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Xanthine dehydrogenase
  • Xanthine dehydrogenase/oxidase
  • 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE-CARBOXYLIC ACID
  • CHEMBL1164729
  • FEBUXOSTAT
23 IC50 3 EC50
  • 11-beta-hydroxysteroid dehydrogenase
  • 11-beta-hydroxysteroid dehydrogenase 1
  • 11-beta-hydroxysteroid dehydrogenase 2
  • 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II
  • Bile acid receptor
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1)
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • Potassium voltage-gated channel subfamily H member 2
  • CHEMBL1829763
  • US8592410, 88
  • US8592410, Comparator 3
  • US8598163, 61
7 Ki 16 IC50 3 EC50
  • Androgen Receptor
  • Estrogen receptor
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • Progesterone receptor
  • ONAPRISTONE
  • ZK-98299
26 IC50
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BRAF/CRAF
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Casein kinase II subunit alpha
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 2
  • DNA polymerase beta
  • DNA polymerase kappa
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase kinase kinase 8
  • NUAK family SNF1-like kinase 1
  • Platelet-derived growth factor receptor beta
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
  • TALAROFLAVONE
20 Ki 3 IC50 3 EC50
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Adenosine A1 receptor
  • Adenosine receptor
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A3
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Transmembrane domain-containing protein TMIGD3
  • CHEMBL2012686
26 IC50
  • ALK tyrosine kinase receptor
  • BDNF/NT-3 growth factors receptor
  • Cytoplasmic tyrosine-protein kinase BMX
  • Ephrin type-A receptor 3
  • Ephrin type-B receptor 2
  • Fibroblast growth factor receptor
  • High affinity nerve growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor 1 receptor
  • JNK1/JNK2
  • Macrophage colony-stimulating factor 1 receptor (c-Fms)
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Neuronal proto-oncogene tyrosine-protein kinase Src
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase ROS
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor-type tyrosine-protein kinase FLT3
  • TPR/MET fusion protein
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor Tie-1
  • Vascular endothelial growth factor receptor 1
  • CHEMBL2037226
15 IC50 11 EC50
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Nonstructural protein 5A
  • BMS-790052
  • DACLATASVIR
26 Ki
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • CHEMBL2323140
18 Ki 8 IC50
  • DNA-dependent protein kinase
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase catalytic subunit type 3
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
  • 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide
  • CHEMBL2387080
  • GDC 0032
  • GDC-0032
  • Roche RG7604
  • Taselisib
  • US10851091, Compound taselisib
  • US8242104, Compound 196
26 IC50
  • 72 kDa type IV collagenase
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-9
  • CHEMBL2431027
20 IC50 3 Kd 3 EC50
  • Baculoviral IAP repeat-containing protein 2
  • Baculoviral IAP repeat-containing protein 3 (IAP1 BIR3)
  • X-linked inhibitor of apoptosis protein (XIAP)
  • CHEMBL2431768
26 IC50
  • Penicillin-binding protein 1A
  • Penicillin-binding protein 2B
  • Penicillin-binding protein 2x
  • CHEBI:51257
  • FAROPENEM
  • Faropenem
16 IC50 10 EC50
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Sphingosine 1-phosphate receptor 1
  • Sphingosine 1-phosphate receptor 3
  • Sphingosine 1-phosphate receptor 4
  • Sphingosine 1-phosphate receptor 5
  • CHEMBL4458575
2 Ki 24 IC50
  • Acetylcholinesterase
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Cholinesterase
  • CHEMBL4571763
5 Ki 9 IC50 12 Kd
  • ABL
  • ABL Mutant (E255K)
  • ABL Mutant (F359V)
  • ABL Mutant (H396P)
  • ABL Mutant (M351T)
  • ABL Mutant (Q252H)
  • ABL Mutant (T315I)
  • ABL Mutant (T315N)
  • ABL Mutant (Y253F)
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine Kinase c-Kit Mutant (N822K)
  • Tyrosine Kinase c-Kit Mutant (V559D)
  • Tyrosine Kinase c-Kit Mutant (V559D/T670I)
  • Tyrosine- and threonine-specific cdc2-inhibitory kinase
  • Tyrosine-protein kinase Lck
  • 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-7H,8H-pyrido[2,3-d]pyrimidin-7-one
  • 6-(2,6-dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one
  • PD-180970
  • PD180970
18 IC50 8 EC50
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-dependent kinase 11B
  • Cyclin-dependent kinase 2
  • GTP-binding protein (rab7)
  • Glycogen Synthase Kinase-3, beta
  • Insulin-like growth factor I receptor
  • Ras-related C3 botulinum toxin substrate 1
  • Ras-related protein Rab-2A.
  • Serine/threonine-protein kinase 17B (STK17B)
  • cell division cycle 42 (GTP binding protein, 25kDa)
  • ras protein
  • 2-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]-2,3-dihydro-1H-indol-3-one
  • Indirubin
  • Indirubin derivative, 1
  • cid_5318433
17 Ki 6 IC50 3 EC50
  • 5-hydroxytryptamine receptor 2A (5HT2A)
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(4) dopamine receptor
  • DRD1
  • DRD2
  • Dopamine receptor
  • Mu-type opioid receptor
  • (+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
  • 2-aminotetralin-6,7-diol;hydrobromide
  • 6-Amino-5,6,7,8-tetrahydro-naphthalene-2,3-diol
  • 6-amino-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide
  • 6-azanyl-5,6,7,8-tetrahydronaphthalene-2,3-diol;hydrobromide
  • ADTN
  • ADTN, (+)
  • CA inhibitor, 3
  • CHEMBL26736
  • MLS002172466
  • SMR001254097
  • cid_11957526
  • cid_3153
23 Ki 3 EC50
  • Metabotropic Glutamate 1a
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 3
  • Metabotropic glutamate receptor 4 (mGlu4)
  • Metabotropic glutamate receptor 4 (mGluR4)
  • Metabotropic glutamate receptor 5
  • Metabotropic glutamate receptor 6
  • metabotropic glutamate 5a
  • Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Ibotenic acid)
  • CAS_2552-55-8
  • CHEMBL284895
  • Ibotenate
  • Ibotenic acid
  • NSC_1233
26 Ki
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • HTR4
  • Serotonin (5-HT) receptor
  • CAS_109872-41-5
  • NSC_3035240
  • RENZAPRIDE
9 Ki 15 IC50 1 Kd
0 ΔG°
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Caspase-1
  • Caspase-3
  • Caspase-4
  • Caspase-5
  • Caspase-9
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Intestinal fatty acid-binding protein (hIFABP)
  • Liver fatty acid binding protein (rat L-FABP)
  • Multidrug resistance-associated protein 4
  • PAK 1/CDC42
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin-H2 D-isomerase
  • Rho GTPase Rac1/CDC42
  • Serum albumin
  • CAS_74103-07-4
  • KETOROLAC
  • Ketorolac tris salt
  • Toradol
10 Ki 16 IC50
  • Acetylcholinesterase
  • Adrenergic Alpha
  • Bile salt export pump
  • Butyrylcholinesterase (BChE)
  • Butyrylcholinesterase (BuChE)
  • Cholinesterases
  • Cholinesterases; ACHE & BCHE
  • 10-(2-diethylaminopropyl)phenothiazine
  • CHEMBL1200970
  • CHEMBL1206
  • Ethopropazine
  • diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
24 IC50 2 Kd
  • Aurora kinase B
  • BRAF/CRAF
  • Casein kinase I isoform delta
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Epidermal growth factor receptor
  • Heat shock factor protein 1
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase kinase kinase 1
  • Pirin
  • Platelet-derived growth factor subunit A
  • Platelet-derived growth factor subunit B (PDGFB)
  • Receptor-interacting serine/threonine-protein kinase 3
  • Serine/threonine-protein kinase B-raf
  • Serine/threonine-protein kinase Chk1/2
  • US8497274, 32