Compound Name
(alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
|---|
| Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
|---|
BDBM18358
 | 7 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | - α-galactosidase
- α-glucosidase
- β-galactosidase
- Beta-galactosidase
- Beta-glucosidase
- Ceramide glucosyltransferase
- Lysosomal acid glucosylceramidase
- Probable alpha-glucosidase Os06g0675700
- Sucrase-isomaltase
- alpha-Glucosidase (alpha-Glu)
- alpha-glucosidase (Gaa)
| - (2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol
- N-Nonyl-DNJ
|
BDBM21675
 | 0 | 0 | 0 | 30 | 0 | 0 | 0 | 0 | - Bile acid receptor
- Bile acid receptor FXR
- G-protein coupled bile acid receptor 1
| - (4R)-4-[(1S,2S,5R,7S,8R,9R,10S,11S,14R,15R)-8-ethyl-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanoic acid
- 6-ECDCA
- 6-ethyl chenodeoxycholic acid
- 6-ethyl-3,7-dihydroxycholan-24-oic acid
- 6ECDCA
- 6alpha-Ethyl-Chenodeoxycholic Acid
- INT-747
- INT747
- Ocaliva
- US10208081, E6-ECDCA
- US10266560, Example 6-ECDCA
- obeticholic acid
|
BDBM22911
 | 22 | 1 | 0 | 7 | 0 | 0 | 0 | 0 | - HRH3
- Histamine H3 receptor
- Histamine H4 receptor
| - 2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide
- CHEMBL19439
- CHEMBL544911
- Imetit
- {[2-(1H-imidazol-4-yl)ethyl]sulfanyl}methanimidamide
|
BDBM23208
 | 1 | 19 | 3 | 7 | 0 | 0 | 0 | 0 | - Aldo-keto reductase family member 1B10 (AKR1B10)
- Aldose reductase (AR)
- Botulinum neurotoxin type A
- DNA polymerase beta
- G-protein coupled bile acid receptor 1
- GP41
- Glycogen phosphorylase, muscle form
- Human immunodeficiency virus type 1 protease
- Hypoxia-inducible factor prolyl hydroxylase
- Nonstructural protein 5
- Nuclear factor NF-kappa-B
- Oxysterols receptor LXR-alpha
- Oxysterols receptor LXR-beta
- Pancreatic alpha-amylase
- Peroxisome proliferator-activated receptor gamma
- Phosphodiesterase isozyme 4
- Protease
- SUMO1 activating enzyme subunit 1
- Serum albumin
- Zinc finger protein GLI1
| - (1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosane-5-carboxylic acid
- Betulinic Acid, 24
- CHEMBL269277
- cid_64971
|
BDBM236795
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - C-C chemokine receptor type 4
- C-C chemokine receptor type 6 (CCR6)
- C-X-C chemokine receptor type 1
- C-X-C chemokine receptor type 2
- chemokine (C-X-C motif) receptor 3
| - US9388149, 2 (Diastereoisomer 1)
- US9388149, 2 (Diastereoisomer 2)
- US9388149, 2 (Enantiomer 1 of diastereoisomer 1)
- US9388149, 2 (Enantiomer 1 of diastereoisomer 2)
- US9388149, 2 (Enantiomer 2 of diastereoisomer 1)
- US9388149, 2 (Enantiomer 2 of diastereoisomer 2)
- US9580412, Example 2
|
BDBM23954
 | 20 | 7 | 0 | 3 | 0 | 0 | 0 | 0 | - PTGER3
- PTGER4
- PTGIR
- Prostaglandin D Synthase
- Prostaglandin E2 receptor
- Prostaglandin E2 receptor EP1 subtype (EP1)
- Prostaglandin E2 receptor EP2 subtype
- Prostaglandin E2 receptor EP4 subtype
- Prostaglandin F2-alpha receptor
- Prostaglandin Transporter
- Prostanoid DP receptor
- Prostanoid EP1 Receptor
- Prostanoid EP2 Receptor
- Prostanoid EP3 Receptor
- Prostanoid IP receptor
| - 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid
- CHEMBL494
- ILOPROST
- Ventavis
- [3H]-Iloprost
|
BDBM243404
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Lysine-specific histone demethylase 1A
| - N-cyclopentyl-5- ((1R,2R)-2- (tetrahydro-2H- pyran-4-ylamino)- cyclopropyl)thio- phene-3-carboxamide
- US10053456, 38
- US10053456, 39
- US10414761, Example 39
- US9718814, 39
- US9920047, 39
|
BDBM243408
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Lysine-specific histone demethylase 1A
| - 5-((1R,2R)-2- (cyclobutylamino)- cyclopropyl)-N- (tetrahydro-2H- pyran-4- yl)thiophene-3- carboxamide
- US10053456, 42
- US10053456, 43
- US10414761, Example 43
- US9718814, 43
- US9920047, 43
|
BDBM243411
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Lysine-specific histone demethylase 1A
| - 5-((1R,2R)-2-(cis- (4-aminocyclohexyl)- amino)cyclopropyl)- N-(4,4- difluorocyclohexyl)- thiophene-3- carboxamide or5-((1R,2R)-2-(trans-(4-aminocyclohexyl)-amino)cyclopropyl)-N-(4,4-difluorocyclohexyl)-thiophene-3-carboxamide
- US10053456, 45
- US10053456, 46
- US10414761, Example 46
- US9718814, 46
- US9920047, 46
|
BDBM246220
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Coagulation factor XI
- Plasma kallikrein
| - US10183932, Example 144
- US9434690, 125
- US9434690, 141
- US9434690, 142
- US9434690, 143
- US9434690, 144
- US9822102, Example 144
|
BDBM256458
 | 15 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | - Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- GST-Lysine-specific histone demethylase 1A (LSD1)
- Lysine-specific histone demethylase 1A
| - US10329256, Example 2
- US9487512, 2
- US9944601, Example 2
|
BDBM283216
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Lysine-specific histone demethylase 1A
| - 4-[2-(4-amino-piperidin-1-yl)-5- (3-fluoro-4-methoxy-phenyl)-1- methyl-6-oxo-1,6-dihydro- pyrimidin-4-yl]-2-fluoro- benzonitrile
- US10023543, Example 7
- US10023543, Example 85
- US10023543, Example 86
- US10207999, Example 86
- US10328077, Example 86
- US10548896, Example 86
- US10849898, Example 86
- US9573930, Example 86
- US9771329, Example 86
- US9776974, Example 86
|
BDBM31704
 | 0 | 27 | 0 | 3 | 0 | 0 | 0 | 0 | - Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH).
- Bcl-2-related protein A1
- Dual Specificity Protein Phosphatase 1
- Dual specificity phosphatase Cdc25B
- Gag-Pol polyprotein
- Heat Shock 70kDa Protein 1
- Hematopoietic protein-tyrosine phosphatase (HEPTP)
- MKP-3
- diphosphomevalonate decarboxylase
- glutathione S-transferase
- heat shock 70kDa protein 8 isoform 1
- nuclear receptor subfamily 4, group A, member 1
| - MLS000050353
- N-(2,3-di-2-furyl-6-quinoxalinyl)-1-azepanecarboxamide
- N-[2,3-bis(2-furanyl)-6-quinoxalinyl]-1-azepanecarboxamide
- N-[2,3-bis(2-furyl)quinoxalin-6-yl]azepane-1-carboxamide
- N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]azepane-1-carboxamide
- SMR000077614
- cid_2214811
|
BDBM329203
 | 1 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | - 1,3-beta-glucan synthase component GLS2
- Bile salt export pump
- Cytochrome P450 2C9
- Cytochrome P450 2D6
- Cytochrome P450 3A
- Sodium channel alpha subunit
- Sodium channel protein type 2 alpha subunit
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 8 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Voltage-gated sodium channel
| - 4-(5-Chloro-6-((1-Methylcyclopropyl)Methoxy)Pyridin-3-yl)-2-Fluoro-5-Methoxy-N-(Methylsulfonyl)Benzamide
- 4-(5-chloro-6-(2,5-difluorophenoxy)-3-pyridinyl)-2-fluoro-5-methoxy-N-(methylsulfonyl)benzamide
- US9663508, Example 705
|
BDBM34702
 | 5 | 12 | 0 | 13 | 0 | 0 | 0 | 0 | - G protein signalling regulator 19
- Glucose 6-phosphate dehydrogenase (G6PD)
- Induced myeloid leukemia cell differentiation protein Mcl-1
- MPI protein
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- POsterior Segregation family member (pos-1)
- RGS7
- RecName: Full=Zinc finger protein mex-5
- Regulator of G-protein signaling 8
- TCRAV4S1
- Trypanosoma brucei RNA editing ligase 1
- glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
- lens epithelium-derived growth factor p75
- regulator of G-protein signaling 4
- regulator of G-protein signalling 16
- serum albumin precursor
| - (4E)-2,3-dihydroxy-4-[[(4-methyl-2-methylimino-1,3-thiazol-3-yl)amino]methylidene]cyclohexa-2,5-dien-1-one
- (4E)-2,3-dihydroxy-4-[[(4-methyl-2-methylimino-3-thiazolyl)amino]methylidene]-1-cyclohexa-2,5-dienone
- (4E)-2,3-dihydroxy-4-[[(4-methyl-2-methylimino-4-thiazolin-3-yl)amino]methylene]cyclohexa-2,5-dien-1-one
- (4E)-4-[[(4-methyl-2-methylimino-1,3-thiazol-3-yl)amino]methylidene]-2,3-bis(oxidanyl)cyclohexa-2,5-dien-1-one
- (4Z)-2,3-dihydroxy-4-[[(4-methyl-2-methylimino-4-thiazolin-3-yl)amino]methylene]cyclohexa-2,5-dien-1-one
- MLS000564160
- SMR000151701
- cid_5834362
|
BDBM36131
 | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | - α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonic Anhydrase VA
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 9
- Gamma-carbonic anhydrase
- Sodium/iodide cotransporter
| - perchlorate
- sodium perchlorate
|
BDBM43854
 | 27 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | - DNA repair protein RAD51 homolog 1
- Myristoyl-CoA:protein N-myristoyltransferase (Nmt)
| - 2-[(veratroylhydrazono)methyl]benzoic acid
- 2-[[(3,4-dimethoxybenzoyl)hydrazinylidene]methyl]benzoic acid
- 2-[[(3,4-dimethoxyphenyl)carbonylhydrazinylidene]methyl]benzoic acid
- 2-[[[(3,4-dimethoxyphenyl)-oxomethyl]hydrazinylidene]methyl]benzoic acid
- MLS000774113
- SC-58272
- SMR000365110
- cid_958176
|
BDBM473171
 | 0 | 28 | 2 | 0 | 0 | 0 | 0 | 0 | - Cytoplasmic tyrosine-protein kinase BMX
- Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase
- Dual specificity mitogen-activated protein kinase kinase 5
- FLT3-ITD
- Proto-oncogene tyrosine-protein kinase Src
- Tyrosine-protein kinase BRK
- Tyrosine-protein kinase BTK
- Tyrosine-protein kinase Blk
- Tyrosine-protein kinase CSK
- Tyrosine-protein kinase FRK
- Tyrosine-protein kinase Fgr
- Tyrosine-protein kinase Fyn
- Tyrosine-protein kinase Fyn (Y531F)
- Tyrosine-protein kinase Fyn Isoform B
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase ITK/TSK
- Tyrosine-protein kinase Lck
- Tyrosine-protein kinase Lyn
- Tyrosine-protein kinase Yes
- flt3
| - (3R,4S)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1,2-dithiolan-4-ol
- US10844038, Example 43 B.
|
BDBM5
 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | - cyclohexanol
- cyclohexanol-d12
|
BDBM50000041
 | 16 | 13 | 1 | 0 | 0 | 0 | 0 | 0 | - Neurokinin 1 receptor
- Neurokinin 2 receptor
- Neuromedin-K receptor
| - (+) (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
- (+)-(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
- (+/-)(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
- (-) (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
- (-)-(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
- (2-Methoxy-benzyl)-((1R,4S)-2-phenyl-piperidin-4-yl)-amine
- (2-Methoxy-benzyl)-((2S,3S)-2-phenyl-piperidin-3-yl)-amine
- (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
- (2S,3S)-3-(2-Methoxy-benzyloxy)-2-phenyl-piperidine
- (2S,3S)-N-(2-methoxybenzyl)-2-phenylpiperidin-3-amine
- CHEMBL2114310
- CHEMBL441225
- CP 99994
- CP-99994
- Tritiated-(2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
|
BDBM50001733
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - ALK tyrosine kinase receptor
- Axin-1/Glycogen synthase kinase-3 beta
- CaM kinase IV
- Homeodomain-interacting protein kinase 1
- Homeodomain-interacting protein kinase 2 (HIPK2)
- Homeodomain-interacting protein kinase 3
- MAP kinase-activated protein kinase 3
- MAP kinase-activated protein kinase 5
- Mitogen-activated protein kinase 1
- Mitogen-activated protein kinase 10
- Mitogen-activated protein kinase 3
- Mitogen-activated protein kinase 8
- Myotonin-protein kinase
- PAK 1/CDC42
- Proto-oncogene tyrosine-protein kinase Src
- RAC-alpha serine/threonine-protein kinase
- Serine/threonine-protein kinase 24
- Serine/threonine-protein kinase AKT
- Serine/threonine-protein kinase AKT2
- Serine/threonine-protein kinase MARK1
- Serine/threonine-protein kinase MST4
- Serine/threonine-protein kinase Nek1
- Serine/threonine-protein kinase Nek2
- Serine/threonine-protein kinase VRK1
- Serine/threonine-protein kinase c-TAK1
- Serine/threonine-protein kinase pim-2
- Tyrosine-protein kinase BRK
- Tyrosine-protein kinase JAK3
- p21-Activated kinase 2 (PAK2)
- p21-Activated kinase 3 (PAK3)
| |
BDBM50004327
 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- Adrenergic alpha1B
- Alpha-1A adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2C adrenergic receptor
- D(1A) dopamine receptor
- D(1B) dopamine receptor
- D(4) dopamine receptor
- Histamine H1 receptor
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium-dependent dopamine transporter
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
| - (1-Phenethyl-piperidin-4-yl)-phenyl-methanol
- CHEMBL18972
- Glemanserin
- MDL 11,939
- MDL-11939
|
BDBM50014945
 | 21 | 3 | 0 | 6 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
| - 3-(2-aminopropyl)-1H-indol-5-ol
- CHEMBL275854
- alpha-M-5-HT
- alpha-methyl-5-HT
- alpha-methyl-5-hydroxytryptamine
- alpha-methylserotonin
|
BDBM50017698
 | 6 | 15 | 2 | 7 | 0 | 0 | 0 | 0 | - 1,3-beta-glucan synthase component GLS2
- 3C-like proteinase
- 3C-like proteinase (3CL-PRO)
- Adrenergic Alpha
- Angiopoietin-1 receptor
- Bile salt export pump
- Calcium channel
- Calmodulin
- Carboxylesterase 2
- Delta-type opioid receptor
- Kappa-type opioid receptor
- Menin/Histone-lysine N-methyltransferase MLL
- Mu-type opioid receptor
- Neuropeptide Y receptor type 1
- Nociceptin receptor
- Opioid receptors; mu & delta
- P-glycoprotein 1
- Replicase polyprotein 1ab
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type I I alpha subunit
| - 4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N-dimethyl-2,2-diphenylbutanamide
- 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide
- 4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-N,N-dimethyl-2,2-diphenyl-butyramide(loperamide)
- CHEMBL841
- Imodium
- LOPERAMIDE
- LOPERAMIDE HYDROCHLORIDE
- cid_71420
- med.21724, Compound 184
|
BDBM50021655
 | 2 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | - JAK1 (aa 866-1154)
- JAK1/JAK2/TYK2
- JAK1/TYK2
- JAK2 (aa 808-1132)
- JAK2/TYK2
- JAK3 (aa 811-1124)
- JAK3/JAK1
- Non-receptor tyrosine-protein kinase TYK2
- TYK2 (aa 888-1187)
- Tyrosine-protein kinase JAK1
- Tyrosine-protein kinase JAK2
- Tyrosine-protein kinase JAK3
| - DECERNOTINIB
- US10112907, Example 00017
- US10766894, Compound TABLE 1.2
- VRT-831509
- VX-509
|
BDBM50027060
 | 12 | 2 | 0 | 16 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 1A
- Adrenergic alpha1B
- Adrenergic receptor
- Adrenergic receptor alpha
- Adrenergic receptor alpha-2
- Alpha adrenergic receptor (1a and 1d)
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Alpha-1A adrenergic receptor
- Alpha-1D adrenergic receptor
- Alpha-2A adrenergic receptor
- Alpha-2B adrenergic receptor
- Alpha-2C adrenergic receptor
- Imidazoline I1
- Imidazoline receptor 1 (I1R)
- Nischarin
| - 2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole
- 2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)
- CHEMBL13852
- CIRAZOLINE
|
BDBM50028094
 | 7 | 19 | 4 | 0 | 0 | 0 | 0 | 0 | - Bile salt export pump
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- Envelope glycoprotein
- Monoamine transporters; Norepininephrine & dopamine
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Norepinephrine Monoamine transporters
- Sigma non-opioid intracellular receptor 1
- Sodium-dependent dopamine transporter
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
- Transcriptional activator protein luxR
| - (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
- (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
- CHEMBL809
- SERTRALINE
|
BDBM50029772
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Dihydrofolate Reductase (DHFR)
- Dihydrofolate reductase
- Dihydrofolate reductase (DHFR)
| - 5-Methyl-6-[(3,4,5-trimethoxy-phenylamino)-methyl]-pyrido[2,3-d]pyrimidine-2,4-diamine
- CHEMBL23532
|
BDBM50033805
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - 72 kDa type IV collagenase
- A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
- A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 17
- Interstitial collagenase
- Matrix metalloproteinase (2 and 3)
- Matrix metalloproteinase 14
- Matrix metalloproteinase 7
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-9
- Stromelysin-1
| |
BDBM50033808
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - 72 kDa type IV collagenase
- A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
- A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
- Collagenase 3
- Disintegrin and metalloproteinase domain-containing protein 17
- Interstitial collagenase
- Matrix metalloproteinase (2 and 3)
- Matrix metalloproteinase 14
- Matrix metalloproteinase 7
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-9
- Stromelysin-1
| |
BDBM50040241
 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- Dopamine D1 receptor
- Dopamine D1B
- Dopamine receptor
- HTR6
- Muscarinic acetylcholine receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Serotonin (5-HT) receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
| - 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine
- 3-Fluoro-6-(4-methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine(fluperlapine)
- CHEMBL63756
- Fluperlapine
|
BDBM50075183
 | 1 | 11 | 8 | 10 | 0 | 0 | 0 | 0 | - Inositol 1,4,5-trisphosphate binding protein
- Inositol 1,4,5-trisphosphate receptor
- Inositol 1,4,5-trisphosphate receptor type 1
- Inositol 1,4,5-trisphosphate receptor type 2
- Inositol 1,4,5-trisphosphate receptor type 3
- Inositol-trisphosphate 3-kinase A
- Type 1 InsP3 receptor isoform S2
- Type I inositol-1,4,5-trisphosphate 5-phosphatase
| - 1,4,5-Insp3
- 1D-myo-inositol 1,4,5-triphosphate
- 1D-myo-inositol 1,4,5-tris(dihydrogen phosphate)
- 1D-myo-inositol 1,4,5-trisphosphate
- 3,5,6-trioxyphosphate-1,2,4-cyclohexanetriol
- CHEMBL279107
- D-myo-inositol 1,4,5-trisphosphate
- IP3
- InsP3
|
BDBM50075315
 | 2 | 2 | 4 | 22 | 0 | 0 | 0 | 0 | - Peroxisome proliferator-activated receptor
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor alpha (PPAR alpha)
- Peroxisome proliferator-activated receptor delta
- Peroxisome proliferator-activated receptor gamma
| - 5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide
- 5-(2,4-Dioxo-thiazolidin-5-ylmethyl)-2-methoxy-N-(4-trifluoromethyl-benzyl)-benzamide(KRP297)
- CHEMBL24458
- KRP-297
|
BDBM50096279
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - BRAF/CRAF
- Dual specificity mitogen-activated protein kinase kinase 5
- Ephrin type-A receptor 2
- Ephrin type-B receptor 4
- Eukaryotic translation initiation factor 2-alpha kinase 4
- Interleukin-1 receptor-associated kinase 1
- MAP kinase p38
- Mitogen-activated protein kinase kinase kinase 1
- Mitogen-activated protein kinase kinase kinase kinase 5
- Mixed lineage kinase 7
- Protein cereblon/BRAF
- Proto-oncogene tyrosine-protein kinase Src
- RAF proto-oncogene serine/threonine-protein kinase
- RAF serine/threonine protein kinase
- Serine/threonine-protein kinase A-Raf
- Serine/threonine-protein kinase B-raf
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase CSK
- Tyrosine-protein kinase Fyn
- Vascular endothelial growth factor receptor 2
| |
BDBM50101815
 | 1 | 29 | 0 | 0 | 0 | 0 | 0 | 0 | - Adrenergic receptor alpha-2
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Bile salt export pump
- Calcium channel (Type L)
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C8
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2J2
- Cytochrome P450 3A
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Multidrug resistance-associated protein 4
- Quinolone resistance protein norA
- Voltage-dependent L-type calcium channel subunit alpha-1S
| - CHEBI:7550
- NICARDIPINE
- Nicardipine
|
BDBM50104975
 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - 72 kDa type IV collagenase
- ADAM17
- Collagenase 3
- Interstitial collagenase
- Matrix metalloproteinase 10
- Matrix metalloproteinase 15
- Matrix metalloproteinase 16
- Matrix metalloproteinase-12 (MMP12)
- Matrix metalloproteinase-14 (MMP14)
- Matrix metalloproteinase-7 (MMP7)
- Matrix metalloproteinase-9
- Neutrophil collagenase
- Stromelysin-1
| - (8S,11R,12S)-2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmethyl)-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide]
- (8S,11R,12S)-N12-hydroxy-N8-(2-morpholino-2-oxoethyl)-2,10-dioxo-11-((2'-(trifluoromethyl)biphenyl-4-yl)methyl)-1-oxa-3,9-diazacyclopentadecane-8,12-dicarboxamide
- 2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmethyl)-1-oxa-3,9-diaza-cyclopentadecane-8,12-dicarboxylic acid 12-hydroxyamide 8-[(2-morpholin-4-yl-2-oxo-ethyl)-amide]
- CHEMBL325163
|
BDBM50117271
 | 2 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | - Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 2J2
- Multidrug resistance-associated protein 4
- Potassium channel protein TASK-1
- Potassium voltage-gated channel subfamily H member 2
- Sodium channel alpha subunit
- Sodium channel protein type 10 subunit alpha
- Sodium channel protein type 2 alpha subunit
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 7 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Sodium channel protein type I I alpha subunit
- Twik-RElated Potassium (K+) channel 1 (TREK1)
- Voltage-gated L-type calcium channel
- Voltage-gated sodium channel alpha subunit Nav1.1
- Voltage-gated sodium channel subunit alpha Nav1.8
| - 1-(2,6-dimethylphenoxy)-2-propanolamine
- 1-(2,6-dimethylphenoxy)propan-2-amine
- 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine
- 2-(2,6-Dimethyl-phenoxy)-1-methyl-ethylamine(mexiletine)
- CHEMBL558
- MEXILETINE
- Mexitil
|
BDBM50126018
 | 0 | 17 | 0 | 13 | 0 | 0 | 0 | 0 | - Oxysterols receptor LXR-alpha
- Oxysterols receptor LXR-beta
- Peroxisome proliferator-activated receptor
- Peroxisome proliferator-activated receptor alpha (PPAR alpha)
- Peroxisome proliferator-activated receptor delta
| - 2-(3-chloro-4-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid
- CHEMBL23296
- {3-Chloro-4-[3-(7-propyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid
- {3-chloro-4-[(3-{[7-propyl-3-(trifluoromethyl)-1,2-benzisoxazol-6-yl]oxy}propyl)sulfanyl]phenyl}acetic acid
|
BDBM50129720
 | 24 | 3 | 0 | 3 | 0 | 0 | 0 | 0 | - NR2B Channel Blocker
- Peroxisome Proliferator-Activated Receptor gamma/Retinoid X receptor alpha
- Peroxisome proliferator-activated receptor alpha
- Peroxisome proliferator-activated receptor gamma
- Retinoic acid receptor RXR-alpha
- Retinoic acid receptor alpha
- Retinoic acid receptor gamma
- Retinoid X receptor alpha
- Retinoid X receptor beta
- Retinoid X receptor gamma
- Retinoid X receptor gamma/retinoic acid receptor alpha
- Retinoid receptor
| - (2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-phenyl]-3-methyl-octa-2,4,6-trienoic acid
- 7-[3,5-Di-tert-butyl-2-(2,2-difluoro-ethoxy)-phenyl]-3-methyl-octa-2,4,6-trienoic acid
- CHEMBL42314
|
BDBM50136759
 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | - Somatostatin receptor type 1
- Somatostatin receptor type 2
- Somatostatin receptor type 3
- Somatostatin receptor type 4
- Somatostatin receptor type 5
| - (4S,7R,10S,13R,16S,22S,25R)-25-amino-13-(4-aminobutyl)-18-[benzoyl(methyl)carbamoyl]-7,22-dibenzyl-4-carboxy-10-[(1R)-1-hydroxyethyl]-16-(1H-indol-3-ylmethyl)-6,9,12,15,21,24-hexaoxo-1,2-dithia-5,8,11,14,17,18,20,23-octaazacyclohexacosan-19-olate
- Peptide analogue
|
BDBM50151982
 | 7 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 7
- Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)
- Adrenergic receptor alpha-1
- Adrenergic receptor alpha-2
- D(2) dopamine receptor
- D(3) dopamine receptor
- Dopamine receptor
- HTR1D
- HTR4
- HTR6
- Serotonin (5-HT) receptor
- Serotonin 1B/1D receptor
- Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium-dependent serotonin transporter
| - 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide
- CHEMBL439849
- VILAZODONE
|
BDBM50159110
 | 26 | 2 | 2 | 0 | 0 | 0 |
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