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Compound Name:

Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
9 Ki 15 IC50 10 Kd
  • 3',5'-cyclic phosphodiesterase
  • Acetylcholinesterase
  • Adenosine A1 receptor
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A2b
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Chitinase 1
  • Chitinase Mutant (A217G)
  • Chitinase Mutant (D175A)
  • Chitinase Mutant (D246A)
  • Chitinase Mutant (E177A)
  • Chitinase Mutant (E322A)
  • Chitinase Mutant (M243A)
  • Chitinase Mutant (R301K)
  • Chitinase Mutant (T138A)
  • Chitinase Mutant (Y245F)
  • Cholinesterases; ACHE & BCHE
  • Endochitinase B1
  • Multidrug resistance-associated protein 4
  • Phosphodiesterase (TcrPDEC)
  • Phosphodiesterase 4
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • 1-(5-Oxohexyl)theobromine (pentoxifylline)
  • 3,7-dimethyl-1-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
  • 3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydropurine-2,6-dione
  • CHEMBL628
  • Pentoxifylline
  • Pentoxil
  • Pentoxyphylline
7 Ki 26 IC50 1 EC50
  • 20S proteasome
  • Accessory gene regulator protein A
  • Aldose reductase (AR)
  • Casein Kinase II
  • Casein kinase II alpha/beta
  • Casein kinase II subunit alpha
  • Cytochrome P450 1A
  • EBifunctional epoxide hydrolase 2
  • Estradiol receptor beta (ERβ)
  • Estrogen receptor
  • Genome polyprotein
  • Human rhinovirus A protease
  • Leukocyte elastase
  • Procathepsin L
  • Proteasome subunit beta type-1/beta type-5
  • Protein-tyrosine phosphatase 4A3
  • Purinergic receptor P2Y12
  • Serine/threonine-protein kinase pim-1
  • Sialidase 2
  • Tyrosine-protein kinase Lck
  • beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ)
  • beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ)
  • 1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9,10-dione
  • 1,3,8-trihydroxy-6-methylanthra-9,10-quinone
  • CHEMBL289277
  • Emodin
  • med.21724, Compound 24
32 IC50 2 EC50
  • Histone lysine demethylase PHF8
  • Lysine-specific demethylase 2B
  • Lysine-specific demethylase 3B
  • Lysine-specific demethylase 3B (KDM3B)
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 4C (KDM4C)
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 6A (KDM6A)
  • Lysine-specific demethylase 6B
  • Lysine-specific demethylase 7A/7B
  • CPI-455
16 Ki 12 IC50 6 Kd
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • D(2) dopamine receptor
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Norepinephrine transporter
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • 1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine
  • CHEMBL112280
  • CHEMBL286991
  • GBR 12935 Analogue, 36
  • GBR-13,069
6 Ki 21 IC50 3 Kd
0 ΔG°
  • 10 kDa chaperonin
  • 60 kDa chaperonin
  • Calcium channel
  • Coagulation factor VII/tissue factor
  • Cyclooxygenase
  • Cytochrome P450 19A1
  • Cytosolic phospholipase A2 gamma
  • FABP5-ANS
  • Fatty acid-binding protein 4 (FABP4)
  • Fatty acid-binding protein 5 (FABP5)
  • Fatty acid-binding protein 5 (FABP5)(DSm)
  • Fatty acid-binding protein 5 (FABP5)(NLSm)
  • Fatty-acid amide hydrolase 1
  • HSP60/HSP10
  • Mannoprotein ligand-binding domain 2 (Mp1p-LBD2 I332A)
  • Mannoprotein ligand-binding domain 2 (Mp1p-LBD2 V309D)
  • Mannoprotein ligand-binding domain 2 (Mp1p-LBD2)
  • Peroxisome proliferator-activated receptor
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • Sterol 14α-demethylase (CYP51)
  • TBXA2R
  • Thiosulfate sulfurtransferase
  • Trypsin
  • Vanilloid receptor
  • (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
  • Arachidonic acid
  • Arachidonic acid (AA)
  • CHEMBL15594
  • [1-14C]Arachidonic acid
6 Ki 26 IC50 2 EC50
  • Acetylcholinesterase
  • Acyl-CoA: cholesterol acyltransferase (ACAT)
  • Apoptotic peptidase activating factor 1
  • Carboxylesterase 2
  • Caspase-9
  • Cholinesterases
  • Factor XIIa
  • Focal adhesion kinase 1
  • Human rhinovirus A protease
  • Leukocyte common antigen
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • Papain
  • Phospholipase A2
  • Phospholipase C, gamma 1
  • Phospholipase C-beta-3
  • Protein-tyrosine phosphatase 1B
  • Serine/threonine-protein kinase PLK1
  • Telomerase reverse transcriptase
  • Valosin-containing protein
  • cysteine protease ATG4B isoform a
  • nuclear receptor corepressor 2 isoform 2
  • perilipin-1
  • perilipin-5
  • photoreceptor-specific nuclear receptor
  • protein-arginine deiminase type-4
  • tyrosyl-DNA phosphodiesterase 2
  • 1,2-Dione-Based Compound, 14
  • 9,10-dihydrophenanthrene-9,10-dione
  • CHEMBL51931
  • Phenanthrene-9,10 dione
  • cid_6763
34 IC50
  • JAK1 (aa 837-1142)
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK2 (aa 828-1132)
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • ((2R,5S)-5-{2-[(1R)- 1-hydroxyethyl]-1H- imidazo[4,5- d]thieno[3,2- b]pyridin-1- yl}tetrahydro-2H- pyran-2- yl)acetonitrile
  • US10053465, 1
  • US10065963, Compound 1
  • US10125150, Example 1
  • US10370387, Example 20
  • US10479803, Example 1D
  • US10519163, Example 1
  • US10675284, Example 1
  • US9732097, Example 1
  • US9777017, Example 20
  • US9908895, Example 20
12 Ki 20 IC50 2 EC50
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • GST-Lysine Specific Demethylase-1 (LSD1)
  • LSD1/CoREST complex
  • Lysine-specific histone demethylase 1A
  • Lysine-specific histone demethylase 1B
  • US10214477, Example 5
  • US9469597, 4
  • US9670136, 3 (trans)-N1-((1S,2R)-2-phenylcyclopropyl)cyclohexane-1,4-diamine
13 Ki 9 IC50 12 Kd
  • 5-hydroxytryptamine receptor 1A
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(2) dopamine receptor
  • Dipeptidyl peptidase 3
  • Liver fatty acid binding protein (rat L-FABP)
  • Multidrug resistance-associated protein 4
  • Serotonin 1B/1D receptor
  • 2-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
  • Artrenolol
  • Atenolol
  • CHEMBL24
  • Tenormin
  • Tenormine
2 IC50 32 EC50
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor alpha
  • Peroxisome proliferator-activated receptor alpha (PPAR alpha)
  • Peroxisome proliferator-activated receptor delta
  • Peroxisome proliferator-activated receptor gamma
  • 2-{[4-(2-{[(2,4-difluorophenyl)carbamoyl](heptyl)amino}ethyl)phenyl]sulfanyl}-2-methylpropanoic acid
  • CHEMBL278590
  • GW 9578
  • GW-9578
  • GW9578
32 IC50 1 Kd
0 ΔG°
  • Axin-1/Glycogen synthase kinase-3 beta
  • Beta-chymotrypsin
  • Glycogen Synthase Kinase-3, beta
  • Homeodomain-interacting protein kinase 1
  • Malate dehydrogenase
  • Mitogen-activated protein kinase kinase kinase 8
  • Mitogen-activated protein kinase kinase kinase kinase 1
  • NAD-Dependent Deacetylase Sirtuin-1
  • NAD-dependent deacetylase HST2
  • NAD-dependent deacetylase sirtuin 2
  • NAD-dependent protein deacetylase sirtuin-3 (SIRT3)
  • Protein Kinase C
  • Protein kinase C alpha type
  • Ribosomal protein S6 kinase (P70S6K)
  • Ribosomal protein S6 kinase alpha 5
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase PIM
  • Serine/threonine-protein kinase TBK1
  • Serine/threonine-protein kinase VRK1
  • Serine/threonine-protein kinase VRK2
  • Serine/threonine-protein kinase pim-1
  • cAMP-Dependent Protein Kinase (PKA)
  • 3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione Methanesulfonate
  • BIM-9
  • Bisindolylmaleimide 11b
  • Bisindolylmaleimide IX
  • CHEMBL6291
  • ROCHE screening, 57
  • Ro 31-8220
  • Ro31-8220
  • [(3-{3-[4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl)sulfanyl]methanimidamide
30 IC50 4 EC50
  • Apoptotic peptidase activating factor 1
  • Caspase-3
  • Caspase-9
  • DNA recombination protein RecA
  • Dual Specificity Protein Phosphatase 1
  • Dual specificity phosphatase Cdc25B
  • Heat shock protein HSP 90-alpha
  • MKP-3
  • PPP5C protein
  • SUMO-1-specific protease
  • SUMO/sentrin specific peptidase family member 8
  • Serine/threonine-protein kinase PLK1
  • Trypanosoma brucei RNA editing ligase 1
  • Tyrosine-protein kinase ABL1
  • protein phosphatase 1, catalytic subunit, alpha isoform 3
  • tyrosyl-DNA phosphodiesterase 2
  • MLS000085603
  • N-(2-hydroxy-1,3-diketo-indan-2-yl)benzamide
  • N-(2-hydroxy-1,3-dioxo-2,3-dihydro-1H-inden-2-yl)benzamide
  • N-(2-hydroxy-1,3-dioxo-2-indenyl)benzamide
  • N-(2-hydroxy-1,3-dioxoinden-2-yl)benzamide
  • N-[2-oxidanyl-1,3-bis(oxidanylidene)inden-2-yl]benzamide
  • SMR000020538
  • cid_3237318
34 IC50
  • Ataxin-2
  • 4-((3aR,6aS)-5-(5-Cyclopropyl-6-(tetrahydro-2H-pyran-4-yloxy)nicotinoyl)octahydropyrrolo[3,4-c]pyrrole-2-carbonyl)benzenesulfonamide
  • US10654857, Example 2.3
  • US9802944, Example 2
  • US9802944, Example 2.1
  • US9802944, Example 2.3
9 Ki 24 IC50 1 EC50
  • Androgen Receptor
  • Androgen receptor
  • Androgen receptor/Baculoviral IAP repeat-containing protein 2
  • LANA
  • Progesterone receptor
  • 2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
  • 2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide (hydroxy flutamide)
  • 2-Hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide(Hydroxyflutamide)
  • 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide
  • CHEMBL491
  • Eulexin
  • HYDROXYFLUTAMIDE
  • Hydroxyflutamide
  • OH-flutamide
  • Sch 16423
  • US9682960, OH-FLU
  • cid_91649
  • hydroxy-flutamide
13 IC50 21 Kd
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • EFGR (L747-E749del, A750P)
  • EGF-R Tyrosine Kinase Mutant (G719C)
  • EGFR (G719S)
  • EGFR (L861Q)
  • EGFR E746-A750del
  • EGFR L747-S752del, P753S
  • EGFR L747-T750del
  • EGFR S752-I759del
  • Epidermal growth factor receptor
  • Epidermal growth factor receptor(L858R)
  • Epidermal growth factor receptor(L858R, T790M)
  • Receptor tyrosine-protein kinase erbB-2
  • US10246444, Example 40
34 EC50
  • Axin-1/Glycogen synthase kinase-3 beta
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Proto-oncogene Wnt-1
  • US10287267, Compound 1086
  • US10287267, Compound 1087
  • US10287267, Compound 77
  • US10287267, Compound 972
  • US10508099, Compound 972
  • US10556885, Compound 1087
  • US10604514, Compound 6
34 Ki
  • D(2) dopamine receptor
  • G_PROTEIN_RECEP_F1_2 domain-containing protein
  • Glutamate receptor ionotropic, NMDA 1
  • HTR3A
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Sigma non-opioid intracellular receptor 1
  • 3-Allyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • CHEMBL330376
  • SKF 10,047 (+)
  • SKF 10,047 (-)
  • SKF 10047
24 Ki 7 IC50 3 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Opioid receptor
  • Opioid receptors; mu & delta
  • Opioid receptors; mu/kappa/delta
  • Solute carrier family 22 member 1
  • 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one
  • 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(oxymorphone)
  • 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(xymorphone)
  • 10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one
  • CHEMBL963
  • Codoxy
  • Combunox
  • Numorphan
  • OXYMORPHONE
  • Opana
  • Oxycet
  • PERCODAN-DEMI
  • Percocet
  • Percodan
  • Roxicet
  • Roxilox
  • Roxiprin
  • Tylox
  • Tylox-325
34 IC50
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • p110α/p85α
  • p110β/p85α
  • CHEMBL2216863
  • US10065963, Compound 28
  • US10428087, Example 15
  • US10519163, Example 28
  • US10675284, Example 28
  • US10829502, Example 15
  • US9708333, 28
  • US9975907, Example 15
19 Ki 13 IC50 2 Kd
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • D(2) dopamine receptor
  • Dopamine receptor
  • HTR6
  • Metabotropic glutamate receptor 3
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
  • Serotonin 1 (5-HT1) receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • 8-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
  • CHEMBL1204189
  • CHEMBL35057
  • TIOSPERONE
29 IC50 5 Kd
  • Bcr-Abl
  • Heat Shock Protein 90 (Hsp90)
  • Heat shock protein 90, putative
  • Heat shock protein HSP 90
  • Heat shock protein HSP 90-alpha
  • Heat shock protein HSP 90-beta
  • Heat-shock protein 90 (Hsp90)
  • CHEBI:5292
  • GELDANAMYCIN
18 Ki 7 IC50 4 Kd 5 EC50
  • Cytochrome P450 2A13
  • Cytochrome P450 2A6
  • Muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor DM1
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M2 and M5
  • Muscarinic acetylcholine receptor M5
  • (+)-pilocarpine
  • (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one
  • (3S,4R)-3-ethyldihydro-4-((1-methyl-1H-imidazol-5-yl)methyl)-2(3H)-furanone
  • (3S-cis)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone
  • CHEMBL550
  • ISOPTO CARPINE
  • PILOCARPINE
  • PILOCARPINE HYDROCHLORIDE
34 IC50
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Cytoplasmic tyrosine-protein kinase BMX
  • Epidermal growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit alpha
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • MAP kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 3
  • Potassium voltage-gated channel subfamily H member 2
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase receptor FLT3
  • CHEMBL3263640
34 IC50
  • Betaine transporter
  • GABA transporter
  • GABA transporter 1
  • GABA transporter 3
  • Sodium- and chloride-dependent GABA transporter 1
  • (R)-Piperidine-3-carboxylic acid
  • (R)-nipecotic acid
  • CHEMBL77575
  • Nipecotic acid
17 Ki 6 IC50 11 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Nociceptin receptor
  • BUPRENORPHINE
  • Buprenorphine
  • CHEBI:3216
28 Ki 2 IC50 4 Kd
  • Acrosin
  • Coagulation factor III/Factor VIIa (fVIIa)
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1s
  • Glutamate delta 2
  • Kallikrein 5
  • Matriptase
  • Plasminogen
  • Prothrombin
  • Thrombin
  • Thrombin & trypsin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin II
  • Trypsin-1
  • Urokinase-type plasminogen activator
  • Benzamidine (Protonated)
  • CHEMBL20936
  • CHEMBL537204
  • benzamidine
1 Ki 29 IC50 1 Kd 3 EC50
  • 3C-like proteinase
  • 3C-like proteinase (3CL-PRO)
  • Beta amyloid A4 protein
  • Bile salt export pump
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2J2
  • Cytochrome P450 3A
  • Heparanase
  • Histamine N-methyltransferase
  • Histidine-rich protein
  • Phosphoehtnaolamine Methyltransferases 1 (PMT1)
  • Phosphoehtnaolamine Methyltransferases 2 (PMT2)
  • Phosphoethanolamine N-methyltransferase
  • Potassium voltage-gated channel subfamily H member 2
  • Replicase polyprotein 1ab
  • 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
  • AMODIAQUINE
  • CHEMBL682
  • med.21724, Compound 188
10 Ki 21 IC50 3 Kd
  • Adrenaline alpha1
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 3A
  • Cytochrome P450 3A5 (CYP3A5)
  • HIV-1 protease
  • Human immunodeficiency virus type 1 protease
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 4
  • Potassium voltage-gated channel subfamily H member 2
  • Protease
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated potassium channel subunit Kv4.3
  • (3S,4aS,8aS)-2-[(2R,3R)-2-Hydroxy-3-(3-hydroxy-2-methyl-benzoylamino)-4-phenylsulfanyl-butyl]-decahydro-isoquinoline-3-carboxylic acid tert-butylamide; compound with methanesulfonic acid
  • AG-1343
  • CHEMBL1205
  • NELFINAVIR MESYLATE
  • Nelfinavir
  • Viracept
5 Ki 29 IC50
  • AVPR1A
  • Oxytocin receptor
  • Vasopressin V1a receptor
  • Vasopressin V2 Receptor
  • Vasopressin V2 receptor
  • 3-chloro-4-(10,11-dihydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-10-ylcarbonyl)-1-(5-fluoro-2-methylphenylcarboxamido)benzene
  • CHEMBL49429
  • Lixivaptan
  • N-[4-(5H,11H-Benzo[e]pyrrolo[1,2-a][1,4]diazepine-10-carbonyl)-3-chloro-phenyl]-5-fluoro-2-methyl-benzamide
34 Ki
  • GABA A receptor alpha-2/beta-2/gamma-2
  • GABA A receptor alpha-3/beta-2/gamma-2
  • GABA receptor alpha-1/beta-3/gamma-2 subunit
  • GABA receptor alpha-2/beta-3/gamma-2 subunit
  • GABA receptor alpha-3/beta-3/gamma-2 subunit
  • GABA receptor alpha-5/beta-3/gamma-2 subunit
  • GABA receptor alpha-6/beta-3/gamma-2 subunit
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid receptor subunit alpha-2/beta-2
  • Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A))
  • (S)-9-Methoxy-7-oxo-3b,4,5,6-tetrahydro-7H-2,6a,11b-triaza-benzo[g]cyclopenta[e]azulene-3-carboxylic acid ethyl ester
  • 9-Methoxy-7-oxo-3b,4,5,6-tetrahydro-7H-2,6a,11b-triaza-benzo[g]cyclopenta[e]azulene-3-carboxylic acid ethyl ester(MSD)
  • CHEMBL52030
10 Ki 24 IC50
  • 72 kDa type IV collagenase
  • Aminopeptidase
  • Angiotensin-converting enzyme
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 6
  • Dipeptidyl peptidase 4
  • Endothelin-converting enzyme 1 (ECE1)
  • Interstitial collagenase
  • Matrix metalloproteinase-9
  • Meprin A subunit beta
  • Neprilysin
  • Neutrophil collagenase
  • Peptide deformylase
  • Peptide deformylase 1A, chloroplastic
  • Peptide deformylase mitochondrial
  • Stromelysin-1
  • (R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide
  • (R)-N4-hydroxy-N1-((S)-1-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)-2-pentylsuccinamide
  • ACTINONIN
  • CHEMBL308333
  • N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-(R)-pentyl-succinamide
  • N*4*-Hydroxy-N*1*-[1-(2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide
34 IC50
  • ALK tyrosine kinase receptor
  • BDNF/NT-3 growth factors receptor
  • Cytoplasmic tyrosine-protein kinase BMX
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • NT-3 growth factor receptor
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase ROS
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor Tie-1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • CHEMBL3582442
34 IC50
  • ALK tyrosine kinase receptor
  • BDNF/NT-3 growth factors receptor
  • Cytoplasmic tyrosine-protein kinase BMX
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • NT-3 growth factor receptor
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase ROS
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor Tie-1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • CHEMBL3582441
32 Ki 2 IC50
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A2b
  • Adenosine receptor A3
  • 1-(2-(furan-2-yl)-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenylurea
  • 1-(2-Furan-2-yl-8-methyl-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl)-3-phenyl-urea
  • CHEMBL324735
  • MRE 3046F20
34 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • C-C chemokine receptor type 1
  • C-C chemokine receptor type 2
  • C-C chemokine receptor type 3
  • C-C chemokine receptor type 5
  • C-C chemokine receptor type 6 (CCR6)
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin 3a (5-HT3a)/3b (5-HT3b)/3c (5-HT3c)/3d (5-HT3d)/3e (5-HT3e) receptor
  • (R)-N-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenyl)acetamide
  • CHEMBL198949
34 IC50
  • Casein kinase I
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 7
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Focal adhesion kinase 1
  • Glycogen synthase kinase-3
  • Insulin receptor
  • Mitogen-activated protein kinase 1
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Vascular endothelial growth factor receptor
  • cAMP-dependent protein kinase (PKA)
  • 3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine
  • CHEMBL120077
  • JNJ-10198409
30 Ki 2 IC50 2 EC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor beta
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Angiotensin II receptor
  • Cholecystokinin receptor
  • D(2) dopamine receptor
  • Dopamine receptor
  • Endothelin receptor, ET-A/ET-B
  • Muscarinic acetylcholine receptor
  • Nociceptin receptor
  • Opioid receptors; mu/kappa/delta
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin 1B/1D receptor
  • Serotonin 3 receptor (5HT3)
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Somatostatin receptor
  • Translocator protein
  • CHEMBL209821
  • N-(3-(4-(4-(cyclohexylmethylsulfonamido)butyl)piperazin-1-yl)phenyl)acetamide
  • N-{3-[4-(4-cyclohexylmethanesulfonylamino-butyl)-piperazin-1-yl]-phenyl}-acetamide
17 Ki 17 IC50
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Ephrin type-B receptor 3 (EPHB3)
  • Glycogen synthase kinase-3
  • Mitogen-activated protein kinase 1
  • Protein kinase C alpha type
  • Protein kinase C delta type
  • RAC-alpha serine/threonine-protein kinase
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase AKT
  • Tyrosine-protein kinase Fyn
  • (5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one
  • (Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one
  • CHEMBL261644
  • CHEMBL393929
20 Ki 14 IC50
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Acetylcholinesterase
  • Alpha-glucosidase MAL12
  • Alpha-glucosidase MAL62
  • Beta amyloid A4 protein
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase V
  • Carbonic anhydrases; II & IX
  • Dihydroorotate dehydrogenase (fumarate)
  • Hyaluronidase
  • Integrase
  • Tyrosinase
  • Xanthine dehydrogenase
  • (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
  • (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid (10)
  • CHEMBL32749
  • Ferulic acid (M5)
  • ferulic acid
34 Ki
  • 5-hydroxytryptamine receptor 1A
  • Adrenergic receptor beta
  • Alpha-2A adrenergic receptor
  • Cholecystokinin receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Glutamate NMDA receptor; Grin1/Grin2c
  • Glycine receptor alpha-4 chain
  • Histamine H1 receptor
  • Histamine H3 receptor
  • Interleukin-6 receptor alpha chain
  • Kappa-type opioid receptor
  • Leukotriene B4 receptor 1
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Nischarin
  • Opioid receptors; mu & delta
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Thyrotropin-releasing hormone receptor
  • Voltage-gated L-type calcium channel
  • CILANSETRON
  • Cilansetron
  • KC-9946
34 IC50
  • Cytochrome P450
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Mono [ADP-ribose] polymerase PARP16
  • Poly [ADP-ribose] polymerase 1
  • Poly [ADP-ribose] polymerase 10
  • Poly [ADP-ribose] polymerase 12
  • Poly [ADP-ribose] polymerase 14
  • Poly [ADP-ribose] polymerase 15
  • Poly [ADP-ribose] polymerase 2
  • Poly [ADP-ribose] polymerase 4
  • Poly [ADP-ribose] polymerase tankyrase-1
  • Poly [ADP-ribose] polymerase tankyrase-2
  • Protein mono-ADP-ribosyltransferase PARP3
  • Tankyrase 1/2
  • CHEMBL4095003
34 IC50
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Interstitial collagenase
  • Matrix metalloproteinase 17
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Solute carrier family 22 member 8
  • Stromelysin-1
  • (4-[1-methyl-2,4-dioxo-6-(3-phenyl-prop-1-ynyl)-1,4-dihydro-2H-quinazolin-3-ylmethyl]-benzoic acid)
  • 4-((1-methyl-2,4-dioxo-6-(3-phenylprop-1-ynyl)-1,2-dihydroquinazolin-3(4H)-yl)methyl)benzoic acid
  • 4-{[1-METHYL-2,4-DIOXO-6-(3-PHENYLPROP-1-YN-1-YL)-1,4-DIHYDROQUINAZOLIN-3(2H)-YL]METHYL}BENZOIC ACID
  • CHEMBL496942
  • MMP Inhibitor, 5
34 IC50
  • Cytoplasmic tyrosine-protein kinase BMX
  • Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7)
  • Epidermal growth factor receptor
  • Lysyl-tRNA synthetase
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Ribosomal protein S6 kinase alpha 1
  • Serine/threonine-protein kinase NEK2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase RIPK2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FER
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • CHEMBL4095253
23 Ki 10 IC50 1 Kd
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 7 (CDK7)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 9
  • Ferrochelatase R115L (FECH)
  • G1/S-specific cyclin-D1
  • G1/S-specific cyclin-E1
  • Glycogen synthase kinase-3
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Ribosomal protein S6 kinase (P70S6K)
  • Serine/threonine-protein kinase Aurora-C
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • 2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine, 5
  • 4-Methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-amine
  • Aminopyrimidine, 9
  • CHEMBL482967
  • CYC-116
1 IC50 33 Kd
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDC2-like kinase 3 (CLK3)
  • Cyclin-dependent kinase 19
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 3 (CDK3)
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 8
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • Dual specificity protein kinase CLK2
  • Dual specificity protein kinase CLK4
  • Dual specificity protein kinase TTK
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-regulated kinases 1B
  • Extracellular signal-regulated kinase 5 (ERK5)
  • Glycogen synthase kinase-3
  • Interferon-induced, double-stranded RNA-activated protein kinase
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 15
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 4
  • Mitogen-activated protein kinase 6
  • Protein kinase C alpha type
  • Serine/threonine-protein kinase Aurora-C
  • Serine/threonine-protein kinase PCTAIRE-1
  • Serine/threonine-protein kinase PCTAIRE-2
  • Serine/threonine-protein kinase PCTAIRE-3
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK3
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase STK16 (STK16)
  • (R,S)-3-(3-(2,3-dihydroxypropylamino)phenyl)-4-(5-fluoro-1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
  • CHEMBL1082152
1 Ki 33 IC50
  • ALK tyrosine kinase receptor
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Casein kinase I isoform alpha
  • Cyclin-dependent kinase 2
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity mitogen-activated protein kinase kinase 4
  • Dual specificity mitogen-activated protein kinase kinase 6
  • Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7)
  • Epidermal growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit alpha
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • MAP kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 3
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 10
  • Mitogen-activated protein kinase 11
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase 9
  • Rho-associated protein kinase 2
  • Serine/threonine-protein kinase CHK2
  • Serine/threonine-protein kinase MST2
  • Serine/threonine-protein kinase PLK3
  • Serine/threonine-protein kinase TBK1
  • Tyrosine- and threonine-specific cdc2-inhibitory kinase
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • CHEMBL1738710
1 Ki 31 IC50 1 Kd 1 EC50
  • BRAF/CRAF
  • EBifunctional epoxide hydrolase 2
  • Ephrin type-A receptor 2 (EPHA2)
  • Fibroblast growth factor receptor 1
  • Glycine receptor subunit alpha-1
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAF proto-oncogene serine/threonine-protein kinase
  • RET kinase mutant (V804L)
  • RET kinase mutant (V804M)
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
  • Vascular endothelial growth factor receptor 3
  • CHEMBL1946170
  • REGORAFENIB
  • US10183928, Regorafenib
  • US10202365, Compound Regorafenib
  • US10227329, Compound Regorafenib
  • US10464902, Regorafenib
  • US10584114, Compound Regorafenib
  • US10774070, Compound Regorafenib
26 Ki 8 IC50
  • 1,3-beta-glucan synthase component GLS2
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Histamine H1 receptor
  • Potassium voltage-gated channel subfamily H member 2
  • CHEMBL85606
  • SB-277011
34 IC50
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • CaM kinase IV
  • Cyclin-dependent kinase 2
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 2
  • Insulin-like growth factor I receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase kinase kinase 9 (MLK1)
  • Myotonin-protein kinase
  • PAK 1/CDC42
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Protein delta homolog 1
  • RAF proto-oncogene serine/threonine-protein kinase
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase PAK 4
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase/endoribonuclease IRE1 Alpha
  • Tyrosine-protein kinase CTK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • p21-Activated kinase 2 (PAK2)
  • CHEMBL2332840
34 IC50
  • Aurora kinase B
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Focal adhesion kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase 9 (MLK1)
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • Mitogen-activated protein kinase kinase kinase kinase 4
  • Myosin light chain kinase, smooth muscle
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase CHK2
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Yes
  • CHEMBL2333445
34 Kd
  • CaM kinase I alpha
  • CaM kinase I delta
  • CaM kinase I gamma
  • Chaperone activity of bc1 complex-like, mitochondrial
  • Citron Rho-interacting kinase
  • Cyclin-dependent kinase 11A
  • Cyclin-dependent kinase 7
  • Death-associated protein kinase 1
  • Death-associated protein kinase 2
  • Death-associated protein kinase 3
  • Dual specificity mitogen-activated protein kinase kinase 4
  • Dual specificity mitogen-activated protein kinase kinase 6
  • Dual specificity protein kinase TTK
  • Extracellular signal-regulated kinase 5 (ERK5)
  • Interferon-induced, double-stranded RNA-activated protein kinase
  • LIM domain kinase 1
  • LIM domain kinase 2
  • MAP kinase-interacting serine/threonine-protein kinase 1
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 15
  • Mitogen-activated protein kinase 4
  • Mitogen-activated protein kinase 6
  • Myosin light chain kinase family member 4
  • NUAK family SNF1-like kinase 2
  • PITSLRE serine/threonine-protein kinase CDC2L1
  • Platelet-derived growth factor receptor beta
  • Ribosomal protein S6 kinase alpha 1
  • Serine/threonine-protein kinase 17A
  • Serine/threonine-protein kinase DCLK3
  • Serine/threonine-protein kinase NEK7
  • Serine/threonine-protein kinase Nek1
  • Serine/threonine-protein kinase Nek5
  • Tyrosine-protein kinase STK16 (STK16)
  • Uncharacterized aarF domain-containing protein kinase 4
  • CHEMBL2425628
6 Ki 13 IC50 14 Kd 1 EC50
  • 1,3-beta-glucan synthase component GLS2
  • ITGA5/ITGB1
  • ITGAV/ITGB1
  • ITGAV/ITGB3
  • ITGAV/ITGB5
  • ITGAV/ITGB6
  • ITGAV/ITGB8
  • CHEMBL4241824
7 IC50 27 EC50
  • Epithelial discoidin domain-containing receptor 1
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • CHEMBL4577779
18 IC50 10 Kd 6 EC50
  • 1,3-beta-glucan synthase component GLS2
  • 3',5'-cyclic phosphodiesterase
  • Acetylcholinesterase
  • Amine oxidase (flavin-containing) A
  • Aryl hydrocarbon receptor
  • Beta-2 adrenergic receptor
  • CGMP-dependent protein kinase
  • Calcium-dependent protein kinase 1
  • Calcium-dependent protein kinase 4
  • Casein kinase I
  • L-type calcium channel alpha-1c/beta-2/alpha2delta-1
  • Nuclear receptor subfamily 1 group I member 2
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • CHEMBL4591417
32 Ki 2 Kd
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 2C (5HT2C)
  • Adrenergic receptor alpha-2
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Serotonin (5-HT) receptor
  • Serotonin 1d (5-HT1d) receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent serotonin transporter
  • SB 200646
  • SB200646a
1 Ki 33 IC50
  • Acetylcholinesterase
  • Butyrylcholinesterase (BChE)
  • Butyrylcholinesterase (BuChE)
  • Cholinesterases
  • Cholinesterases; ACHE & BCHE
  • Muscarinic acetylcholine receptor M1
  • Trypanothione reductase
  • 6-chloro-1,2,3,4-tetrahydroacridin-9-amine
  • 6-chlorotacrine
  • 6-chlorotacrine.HCl
  • CHEMBL486698
  • Tacrine Analogue 4