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Compound Name:

Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
46 Ki
  • β-Carbonic anhydrase 2 (CA 2)
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • beta-Carbonic Anhydrase
  • 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide
  • CHEMBL360356
  • Chlorzolamide, CHL
  • JMC522226 Compound 19
  • JMC523116 Compound 19
  • aromatic/heteroaromatic sulfonamide 20
44 Ki 2 IC50
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • 2-Hydrazinobenzenesulfonamide
  • 2-hydrazinylbenzene-1-sulfonamide
  • CHEMBL176495
  • aromatic/heteroaromatic sulfonamide 24
  • hydrazide deriv. 18
3 Ki 19 IC50 7 Kd 13 EC50
0 ΔG°
  • DNA-dependent protein kinase
  • Heat Shock Protein 90 (Hsp90)
  • Heat shock protein 75 kDa, mitochondrial
  • Heat shock protein 90 beta
  • Heat shock protein HSP 90-alpha
  • Heat shock protein HSP 90-beta
  • Receptor tyrosine-protein kinase erbB-2
  • (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • 17-(Allylamino)geldanamycin
  • 17-AAG
  • 17AAG
  • CHEMBL109480
  • GLD-36
  • Tanespimycin
3 Ki 42 IC50 1 EC50
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 2
  • Cereblon/Histone deacetylase 6
  • Histone deacetylase
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Nicotinamide phosphoribosyltransferase
  • Nuclear receptor corepressor 1
  • 4-(acetylamino)-N-(2-amino-phenyl) benzamide
  • CI-994
  • N-(2-aminophenyl)-4-acetamidobenzamide
  • N-acetyldinaline
46 Ki
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • Beta-2 adrenergic receptor
  • Calcium channel
  • Calcium release-activated calcium channel
  • Cholecystokinin receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Glutamate receptor ionotropic, NMDA 1
  • Glycine
  • Glycine, non-strychnine
  • HRH3
  • HTR1D
  • HTR3A
  • HTR4
  • Histamine H1 receptor
  • Histamine H2 receptor
  • Histamine H3 receptor
  • Histamine H4 receptor
  • Imidazoline I1
  • Kappa-type opioid receptor
  • Melatonin
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Opioid receptors; mu & delta
  • Serotonin 1B/1D receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Substance P
  • Voltage-gated sodium channel subunit alpha Nav1.8
  • adrenergic Alpha2
  • CHEMBL1237146
  • CHEMBL498770
  • Iodophenpropit
  • {[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide
46 Ki
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • (S)-(3-(dimethylamino)-3-methylazetidin-1-yl)(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-5-propyl-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-6-yl)methanone
  • US10196393, Example 8
  • US10196393, Example 8-1
  • US10196393, Example 8-10
  • US10196393, Example 8-11
  • US10196393, Example 8-12
  • US10196393, Example 8-13
  • US10196393, Example 8-15
  • US10196393, Example 8-16
  • US10196393, Example 8-17
  • US10196393, Example 8-18
  • US10196393, Example 8-19
  • US10196393, Example 8-2
  • US10196393, Example 8-20
  • US10196393, Example 8-21
  • US10196393, Example 8-3
  • US10196393, Example 8-4
  • US10196393, Example 8-5
  • US10196393, Example 8-6
  • US10196393, Example 8-7
  • US10196393, Example 8-8
  • US10196393, Example 8-9
  • US10550118, Example 8
4 Ki 40 IC50 1 Kd 1 EC50
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
  • Acetylcholinesterase
  • Bfl-1
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cereblon/Histone deacetylase 6
  • Cholinesterase
  • Cystic fibrosis transmembrane conductance regulator
  • HMG-CoA reductase
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Integrin alpha-L/beta-2 (LFA-1)
  • Integrin beta-2/Leukocyte adhesion glycoprotein LFA-1 alpha
  • Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2
  • Multidrug resistance-associated protein 4
  • P-glycoprotein 1
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Sterol 14α-demethylase (CYP51)
  • LOVASTATIN
  • MLS000069585
  • SMR000058779
  • US9115116, lovastatin
  • US9353061, Lovastatina
  • cid_53232
9 Ki 33 IC50 4 Kd
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neurokinin 3 receptor
  • Neuromedin-K receptor
  • TACR2
  • TACR3
  • ((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
  • ((S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
  • (+)(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
  • (-) (2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
  • (2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
  • CHEMBL16192
  • CP-96,345
  • CP-96345
  • i(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
33 Ki 5 IC50 8 EC50
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • (2R,6R,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • 3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • CHEMBL56585
  • Cyclazocine
  • US10231963, Table B.9
  • US10736890, Compound TABLE B.9
  • US9656961, Example 00126
9 Ki 37 IC50
  • Dihydrofolate reductase
  • Dihydrofolate reductase (DHFR)
  • GAR transformylase
  • Thymidylate Synthase (TS)
  • Thymidylate synthase
  • 2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)methyl)(prop-2-ynyl)amino)benzamido)pentanedioic acid
  • 2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
  • 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid
  • 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid (PDDF)
  • 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(N10-propargyl-5,8-dideazafolate, PDDF)
  • 2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-benzoylamino}-pentanedioic acid(PDDF)
  • CHEMBL422395
  • PDDF
42 Ki 3 IC50 1 EC50
  • 5-hydroxytryptamine receptor 2A
  • ANF
  • Adenosine Kinase (AK)
  • Adenylate cyclase Forskolin
  • Alpha-1A adrenergic receptor
  • Angiotensin
  • Arg-vasopressin V1
  • Beta-2 adrenergic receptor
  • Bombesin
  • Calcium channel
  • Chloride channel, TBOB
  • Cholecystokinin receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • DRD1
  • EGF
  • Ecto-5'-nucleotidase (e5'NT)
  • GRIA3
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid type B receptor subunit 1
  • Glutamate receptor ionotropic, NMDA 1
  • Glutamate receptor ionotropic, kainate 1
  • Glycine
  • Inositol Triphosphate
  • Interleukin
  • NGF
  • Norepinephrine transporter
  • Potassium Channel
  • SOMATOSTATIN
  • Sigma non-opioid intracellular receptor 1
  • Substance K
  • VIP
  • adrenergic Alpha2
  • (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine
  • (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol
  • 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol
  • CHEMBL43345
  • Dihydrexidine, DHX
40 Ki 6 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Adrenergic alpha1B
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine D1 receptor
  • Dopamine receptor
  • HTR6
  • HTR7
  • Histamine H1 receptor
  • Multidrug resistance-associated protein 4
  • Serotonin (5-HT) receptor
  • 9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10a-octahydro-indolo[4,3-fg]quinoline; compound with methanesulfonic acid
  • CHEMBL1275
  • LY-127809
  • PERGOLIDE MESYLATE
  • Pergolide
  • Permax
1 Ki 38 IC50 6 Kd
0 ΔG°
  • Cyclooxygenase-2 (COX-2)
  • Glucocorticoid receptor
  • Human papillomavirus regulatory protein E2
  • Nuclear receptor ROR-alpha
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Regulatory protein E2
  • Similar to alpha-tubulin isoform 1
  • Steroidogenic Factor 1
  • Tubulin
  • Tubulin alpha chain /beta chain
  • Tubulin beta chain
  • nuclear receptor subfamily 0 group B member 1
  • CHEMBL61
  • PODOFILOX
  • Podophyllinic acid lactone
  • Podophyllotoxin (PTOX)
  • podophyllotoxin
10 Ki 36 IC50
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome P450 19A1
  • Dipeptidyl peptidase 3
  • Leukotriene A4 hydrolase
  • Multidrug resistance-associated protein 4
  • Myeloperoxidase (MPO)
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Serum albumin
  • CHEMBL56367
  • nimesulide
5 Ki 36 IC50 5 EC50
  • ATP-binding cassette sub-family G member 2
  • Cytochrome P450 1A
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Human immunodeficiency virus type 1 reverse transcriptase
  • Human immunodeficiency virus type 2 integrase
  • Integrase
  • Multidrug resistance-associated protein 2 (MRP2)
  • P-glycoprotein 1
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sigma-2 receptor
  • Solute carrier family 22 member 2
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
  • Vesicular acetylcholine transporter
  • CHEBI:76010
  • DOLUTEGRAVIR
  • Dolutegravir
  • GSK1349572
  • S-349572
11 Ki 35 IC50
  • 72 kDa type IV collagenase
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
  • (S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide
  • (S)-N-hydroxy-2,2-dimethyl-4-(4-(pyridin-4-yloxy)phenylsulfonyl)thiomorpholine-3-carboxamide
  • 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide
  • 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(AG 3340)
  • 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(prinomastat)
  • AG-3340
  • CHEMBL75094
  • Prinomastat
5 Ki 17 IC50 2 Kd 22 EC50
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • CDGSH iron-sulfur domain-containing protein 1
  • CDGSH iron-sulfur domain-containing protein 2
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • PPAR alpha/gamma
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor alpha
  • Actos
  • CHEBI:8228
  • Duetact
  • PIOGLITAZONE
  • Pioglitazone
  • US10188639, Compound h-rac-pio
12 Ki 32 IC50 2 EC50
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Lysine-specific histone demethylase 1A
  • Lysine-specific histone demethylase 1B
  • Lysyl oxidase homolog 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Trypsin-1
  • (+/-)-Tranylcypromine
  • 2-PCPA
  • 2-Phenyl-cyclopropylamine
  • 2-phenylcyclopropanamine
  • CHEMBL313833
  • TRANYLCYPROMINE
  • Tranylcypromine,(+)
  • Tranylcypromine,(-)
  • US8609708, 6 Tranyl- cypromine
  • US8609708, 6 Tranylcypromine
43 Ki 3 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine D1 receptor
  • Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
  • CHEMBL59725
  • N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide
46 IC50
  • Bromodomain testis-specific protein
  • Bromodomain-containing protein 4
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • DINACICLIB
  • Dinaciclib
  • MK-7965
  • SCH-727965
2 Ki 43 IC50 1 Kd
  • Aldehyde oxidase
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Shiga toxin subunit A
  • Tyrosinase
  • Xanthine dehydrogenase
  • Xanthine dehydrogenase/oxidase
  • ALLOPURINOL
  • Allopurinol
  • Aloral
  • Aluline 100
  • Aluline 300
  • BW-56-158
  • BW-56158
  • CHEBI:40279
  • Caplenal
  • Cosuric
  • Hamarin 100
  • Hamarin 300
  • Ledopur
  • Lopurin
  • Uricto
  • Xanthomax-100
  • Xanthomax-300
  • Zyloprim
  • Zyloric
  • Zyloric-300
44 Ki 2 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • GRM8
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Histamine H3 receptor
  • Histamine H4 receptor
  • Kappa-type opioid receptor
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 4 (mGluR4)
  • Metabotropic glutamate receptor 6
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • 3-fluoro-5-(2-(2-(fluoromethyl)thiazol-4-yl)ethynyl)benzonitrile
  • CHEMBL229429
46 IC50
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • CDK2/Cyclin A/Cyclin A1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Epidermal growth factor receptor
  • Eukaryotic elongation factor 2 kinase
  • Fibroblast growth factor receptor 1
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit alpha
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • MAP kinase-activated protein kinase 2
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitotic checkpoint serine/threonine-protein kinase BUB1
  • Pancreatic endoplasmic reticulum kinase (PERK)
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase MST4
  • Serine/threonine-protein kinase NEK6
  • Serine/threonine-protein kinase PAK 4
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • Tyrosine kinase non-receptor protein 2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
  • 8-[(1-Acetylpiperidin-4-yl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide
  • CHEMBL599224
46 IC50
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A3
  • Anandamide amidohydrolase
  • Angiotensin II receptor
  • BDKRB2
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • C-C chemokine receptor type 1
  • C-X-C chemokine receptor type 2
  • Cannabinoid receptor 1
  • Cannabinoid receptor 2
  • Cholecystokinin receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Dopamine receptor D2L/neurotensin receptor NTS1
  • Endothelin-1 receptor
  • Galanin receptor 2
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Kappa-type opioid receptor
  • Melanocortin receptor 4
  • Melatonin receptor
  • Monoacylglycerol lipase ABHD12
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Neurokinin 2 receptor
  • Neuromedin-K receptor
  • Neuropeptide Y receptor type 1
  • Neuropeptide Y receptor type 2
  • Nociceptin receptor
  • Prostanoid TP receptor
  • Serotonin 1B/1D receptor
  • Small conductance calcium-activated potassium channel
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • Transient receptor potential cation channel subfamily V member 1
  • Vasopressin V1a receptor
  • 1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
  • CHEMBL1210154
2 Ki 44 IC50
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto reductase family 1 member C4 (AK1C4)
  • Aldo-keto-reductase family 1 member C3
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Caspase-1
  • Caspase-3
  • Caspase-4
  • Caspase-5
  • Caspase-9
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome P450 2J2
  • Dihydrofolate reductase
  • Multidrug resistance-associated protein 4
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Prostaglandin-H2 D-isomerase
  • Seed lipoxygenase-1
  • Solute carrier family 22 member 6
  • (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
  • (S)-2-(6-Methoxy-naphthalen-2-yl)-propionic acid
  • (S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
  • (S)-naproxen
  • 2-(6-Methoxy-naphthalen-2-yl)-propionic acid
  • 2-(6-Methoxy-naphthalen-2-yl)-propionic acid(naproxen)
  • 2-(6-methoxy-2-naphthyl)propanoic acid
  • 2-(6-methoxynaphthalen-2-yl)propanoic acid
  • Aleve
  • Anaprox
  • CHEMBL154
  • Ec-naprosyn
  • Equiproxen
  • Naprelan
  • Naprosyn
  • Naproxen
  • Naproxen2-(6-Methoxy-naphthalen-2-yl)-propionic acid
  • RS-3540
  • S-NAPROXEN
  • naproxene
5 Ki 4 IC50 37 EC50
  • Bile acid transporter
  • Canalicular multispecific organic anion transporter 1
  • Free fatty acid receptor 1
  • Free fatty acid receptor 2
  • Free fatty acid receptor 3
  • Free fatty acid receptor 4
  • G-protein coupled receptor 120
  • Melanocortin receptor 4
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • CHEMBL1829174
  • CHEMBL2047159
  • TAK-875
45 IC50 1 Kd
  • ALK tyrosine kinase receptor
  • Axin-1/Glycogen synthase kinase-3 beta
  • COUP transcription factor 1
  • Cyclin-dependent kinase 2
  • Epidermal growth factor receptor
  • Epidermal growth factor receptor(L858R)
  • Epidermal growth factor receptor(L858R, T790M)
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • Lysyl-tRNA synthetase
  • MAP kinase-activated protein kinase 2
  • MAP kinase-activated protein kinase 5
  • MAP kinase-interacting serine/threonine-protein kinase 1
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 12
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 9
  • Non-receptor tyrosine-protein kinase TYK2
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Protein kinase N1
  • Protein kinase N2
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Rho-associated protein kinase 2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase WNK1
  • Serine/threonine-protein kinase pim-2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Vascular endothelial growth factor receptor 2
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
  • CHEMBL2178352
  • US9096601, 8-26
46 Kd
  • Carbonic Anhydrase III
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase V
  • Carbonic anhydrases; II & IX
  • CHEMBL4173814
2 Ki 40 IC50 4 EC50
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 4A
  • Lysine-specific demethylase 4B
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 6B
  • CHEMBL4449500
12 IC50 34 Kd
  • ALK tyrosine kinase receptor
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • BDNF/NT-3 growth factors receptor
  • Cyclin-dependent kinase
  • Cyclin-dependent kinase 8
  • Discoidin domain-containing receptor 2
  • Dual specificity mitogen-activated protein kinase kinase 5
  • Epithelial discoidin domain-containing receptor 1
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Homeodomain-interacting protein kinase 4
  • Mast/stem cell growth factor receptor Kit
  • Serine/threonine-protein kinase 10
  • Serine/threonine-protein kinase 2
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • CHEMBL4571241
28 Ki
0 ΔG°
  • HIV-1 Protease
  • HIV-1 Protease A Subtype
  • HIV-1 Protease A Subtype Mutant (V82F/I84V)
  • HIV-1 Protease AE
  • HIV-1 Protease AE Mutant (V82F)
  • HIV-1 Protease AE-P
  • HIV-1 Protease AE-P Mutant (F82V)
  • HIV-1 Protease B Subtype
  • HIV-1 Protease B Subtype Mutant (V82F)
  • HIV-1 Protease B Subtype Mutant (V82F/I84V)
  • HIV-1 Protease C Subtype
  • HIV-1 Protease C Subtype Mutant (V82F/I84V)
  • HIV-1 Protease Mutant (A71V)
  • HIV-1 Protease Mutant (D30N)
  • HIV-1 Protease Mutant (D30N/A71V)
  • HIV-1 Protease Mutant (D30N/M36I)
  • HIV-1 Protease Mutant (D30N/M36I/A71V)
  • HIV-1 Protease Mutant (L10I/L90M)
  • HIV-1 Protease Mutant (M36I)
  • HIV-1 Protease Mutant (M36I/A71V)
  • HIV-1 Protease Mutant (M46I/I54V)
  • HIV-1 Protease Mutant (V82A/I84V)
  • HIV-1 Protease Mutant (V82F/I84V)
  • HIV-1 Protease Mutant V6
  • HIV-1 Protease Mutant V6(46)
  • HIV-1 Protease Mutant V6(46/54/84)
  • HIV-1 Protease Mutant V6(46/84)
  • HIV-1 Protease Mutant V6(54)
  • HIV-1 Protease Mutant V6(54/84)
  • HIV-1 Protease Mutant V6(84)
  • HIV-1 Protease Mutant, A-1
  • HIV-1 Protease Mutant, ANAM-11
  • HIV-1 Protease Mutant, MDR-HM
  • HIV-1 Protease Mutant, MDR-QM
  • HIV-1 Protease Mutant, NAM-10
  • HIV-1 protease
  • (3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide
  • AG-1343
  • CHEMBL584
  • Nelfinavir
  • Viracept
7 Ki 39 EC50
  • Bcl-2-like protein 11
  • GRM7
  • GRM8
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 3
  • Metabotropic glutamate receptor 4 (mGlu4)
  • Metabotropic glutamate receptor 4 (mGluR4)
  • Metabotropic glutamate receptor 5
  • Metabotropic glutamate receptor 6
  • Metabotropic glutamate receptor 6 (mGlu6)
  • Metabotropic glutamate receptor 7 (mGlu7)
  • Metabotropic glutamate receptor 8
  • Phospholipase C-beta-1
  • (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;hydrate
  • (1S,3R)-1-azanylcyclopentane-1,3-dicarboxylic acid;hydrate
  • CHEMBL34453
  • MLS002153209
  • SMR001230688
  • cid_16218853
  • trans-( )-ACPD monohydrate
34 Ki 12 IC50
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Adenosine A1 receptor
  • Adenosine A2 receptor
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Alpha-1A adrenergic receptor
  • Beta-1 adrenergic receptor
  • CCKBR
  • Calcium channel (DHP)
  • Calcium release-activated calcium channel
  • Coagulation factor X
  • Coagulation factor XI
  • Cysteinyl leukotriene receptor 1
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Glycine
  • HTR1D
  • HTR2C
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Opioid receptors; mu & delta
  • Plasma kallikrein
  • Plasminogen
  • Prothrombin
  • Serotonin 1B/1D receptor
  • Sodium-dependent serotonin transporter
  • Substance K
  • TRH
  • Tissue-type plasminogen activator
  • Trypsin
  • Urokinase-type plasminogen activator
  • Urokinase-type plasminogen activator (uPA)
  • Urokinase-type plasminogen activator/surface receptor
  • Vitamin K-dependent protein C
  • adrenergic Alpha2
  • CAS_1794
  • CHEMBL1909810
  • HMA
  • NSC_1794
7 Ki 13 IC50 26 EC50
  • Melanocortin receptor 1
  • Melanocortin receptor 3
  • Melanocortin receptor 4
  • Melanocortin receptor 5 (MC5R)
  • Melanocyte-stimulating hormone receptor
  • CAS_75921-69-6
  • NDP-MSH
46 Ki
  • 5-hydroxytryptamine receptor 2A
  • AGTR1
  • AGTR2
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor A1
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Aldose reductase (ALR2)
  • Angiotensin-converting enzyme
  • BDKRB2
  • Beta-1 adrenergic receptor
  • COX-1
  • Caspase-3
  • Cholecystokinin
  • Cholinergic, Nicotinic Muscle
  • Cholinergic, muscarinic
  • Corticotropin releasing factor receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Endothelin-1 receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid type B receptor subunit 1
  • Glucocorticoid
  • Glutamate receptor ionotropic, NMDA 1
  • Histamine H1 receptor
  • Insulin
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Nanos homolog 2
  • Neurokinin 1 receptor
  • Neuropeptide Y
  • Nitric oxide synthase, endothelial
  • Phosphodiesterase 1
  • Phosphodiesterase 3
  • Phosphodiesterase 5
  • Platelet-derived growth factor subunit B (PDGFB)
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Serotonin 1B/1D receptor
  • Sigma non-opioid intracellular receptor 1
  • VIPR1
  • Voltage-dependent T-type calcium channel subunit alpha-1H
  • atrial natriuretic peptide, ANP
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • hIL-1beta
  • N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyformamidine
  • TS-011
41 Ki 5 IC50
  • D(3) dopamine receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Norepinephrine Monoamine transporters
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • 3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-aza-bicyclo[3.2.1]octane
  • 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane
  • 3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-azonia-bicyclo[3.2.1]octane
  • 4,4'-DifluoroBZT
  • CHEMBL317757
  • CHEMBL543113