Compound Name
(alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
|---|
| Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
|---|
BDBM142598
 | 0 | 32 | 21 | 0 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 2A
- Axin-1/Glycogen synthase kinase-3 beta
- Calmodulin/Proto-oncogene tyrosine-protein kinase Src
- Glycogen synthase kinase-3
- Glycogen synthase kinase-3 beta
- Mitogen-activated protein kinase 12
- Mitogen-activated protein kinase 12 Gamma
- Mitogen-activated protein kinase 14
- Proto-oncogene tyrosine-protein kinase Src
- SRC
- Tyrosine-protein kinase HCK
- Tyrosine-protein kinase SYK
- hck
| - US10238658, Example Reference
- US10813932, Reference Compound
- US8933228, Ref 2
- US9242960, 1
- US9249125, Reference Compound
- US9701670, Reference Compound
- US9724347, Example Reference
- US9993478, Example Reference
|
BDBM19187
 | 6 | 45 | 1 | 1 | 0 | 0 | 0 | 0 | - Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Monoamine Oxidase Type B (MAO-B)
- Monoamine oxidase
- Sodium channel protein type 9 subunit alpha
| - (2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl)amino]propanamide
- CHEMBL396778
- SAG
- Safinamide
- US9051240, (S)-(+)-2-[4-(3-Fluorobenzyloxy)-benzylamino]-propanamide
|
BDBM214799
 | 27 | 0 | 0 | 26 | 0 | 0 | 0 | 0 | - κ opioid receptor (KOR D138A)
- κ opioid receptor (KOR D138N)
- κ opioid receptor (KOR E297A)
- κ opioid receptor (KOR H291A)
- κ opioid receptor (KOR H291F)
- κ opioid receptor (KOR I135A)
- κ opioid receptor (KOR I294A)
- κ opioid receptor (KOR I316A)
- κ opioid receptor (KOR K200A)
- κ opioid receptor (KOR K227A)
- κ opioid receptor (KOR L212A)
- κ opioid receptor (KOR M142A)
- κ opioid receptor (KOR M226A)
- κ opioid receptor (KOR Q115A)
- κ opioid receptor (KOR Y119A)
- κ opioid receptor (KOR Y119F)
- κ opioid receptor (KOR Y139A)
- κ opioid receptor (KOR Y139F)
- κ opioid receptor (KOR Y312A)
- κ opioid receptor (KOR Y312F)
- κ opioid receptor (KOR Y313A)
- κ opioid receptor (KOR Y313F)
- κ opioid receptor (KOR Y320A)
- κ opioid receptor (KOR Y320F)
- κ opioid receptor (KOR Y66A)
- Kappa-type opioid receptor
| |
BDBM23419
 | 9 | 40 | 3 | 0 | 0 | 0 | 0 | 0 | - Acetylcholinesterase
- Aldose reductase (AR)
- Alpha-amylase
- Alpha-glucosidase MAL62
- Amine oxidase (flavin-containing) A
- Amine oxidase [flavin-containing] B
- Axin-1/Glycogen synthase kinase-3 beta
- Butyrylcholinesterase (BChE)
- Calmodulin
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 7
- Carbonyl reductase [NADPH] 1
- Cytochrome P450 19A1
- Cytochrome P450 1A
- Cytochrome P450 1A1
- Cytochrome P450 1B1
- Dipeptidyl peptidase 4
- Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1)
- Estradiol 17-beta-dehydrogenase 2
- Glyoxalase I
- Human immunodeficiency virus type 1 integrase
- Inositol hexakisphosphate kinase 2
- Inositol polyphosphate multikinase
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Neuraminidase
- P-glycoprotein (P-gp)
- Pancreatic lipase
- Proteasome subunit beta type-1/beta type-5
- Protein-tyrosine phosphatase 1B
- Testis-specific androgen-binding protein
- Tyrosine-protein kinase receptor FLT3
- Xanthine dehydrogenase/oxidase
| - (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
- CHEMBL9352
- Naringenin
|
BDBM26979
 | 52 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | - α-Carbonic anhydrase (αCA)
- β-Carbonic anhydrase (βCA)
- Alpha carbonic anhydrase
- Alpha-carbonic anhydrase
- Astrosclerin-3
- Axin-1/Glycogen synthase kinase-3 beta
- Beta-carbonic anhydrase
- Carbonic Anhydrase VA
- Carbonic Anhydrase XIII
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Carbonic anhydrase, alpha family
- Gamma-carbonic anhydrase
| - CHEMBL19429
- CHEMBL69710
- CHLORIDE
- Cl-
- POTASSIUM CHLORIDE
- SODIUM CHLORIDE
- chloride
- chloride ion
|
BDBM27135
 | 2 | 45 | 2 | 4 | 0 | 0 | 0 | 0 | - Poly [ADP-ribose] polymerase 1
- Poly [ADP-ribose] polymerase 10
- Poly [ADP-ribose] polymerase 12
- Poly [ADP-ribose] polymerase 14
- Poly [ADP-ribose] polymerase 2
- Poly [ADP-ribose] polymerase 4
- Poly [ADP-ribose] polymerase tankyrase-1
- Poly [ADP-ribose] polymerase tankyrase-2
- Protein mono-ADP-ribosyltransferase PARP3
| - 2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide
- VELIPARIB
- benzimidazole carboxamide, 3a
|
BDBM27507
 | 1 | 52 | 0 | 0 | 0 | 0 | 0 | 0 | - Coagulation factor III/Factor VIIa (fVIIa)
- NAD-Dependent Deacetylase Sirtuin-1
- NAD-dependent deacetylase HST2
- NAD-dependent deacetylase sirtuin 1
- NAD-dependent deacetylase sirtuin 2
- NAD-dependent deacetylase sirtuin 3
- NAD-dependent histone deacetylase SIR2
- NAD-dependent protein deacetylase
- NAD-dependent protein deacetylase sirtuin-3 (SIRT3)
- NAD-dependent protein deacetylase sirtuin-5 (SIRT5)
- Poly [ADP-ribose] polymerase 1
- Putative silent information regulator 2
- Sirtuin-6 (SIRT6)
- poly-ADP-ribose polymerase 2 (PARP2)
| - 3-Pyridinecarboxamide
- CHEMBL1140
- NAM
- niacinamide
- nicotinamide
- pyridine-3-carboxamide
|
BDBM36126
 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | | |
BDBM50001028
 | 44 | 7 | 0 | 2 | 0 | 0 | 0 | 0 | - D(2) dopamine receptor
- DRD1
- Delta-type opioid receptor
- Glutamate receptor ionotropic, NMDA 1
- HTR3A
- Imidazoline I1
- Kappa-type opioid receptor
- Mu-type opioid receptor
- OPRD1
- Opioid receptor
- Sigma intracellular receptor 2
- Sigma non-opioid intracellular receptor 1
- Sigma-1 receptor
- Vesicular acetylcholine transporter
- Zinc finger protein 664
| - (+)-PENTAZOCINE
- (-)-pentazocine
- (2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
- (6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
- 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
- 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)
- CHEMBL560
- PENTAZOCINE (+)
- PENTAZOCINE (-)
- Pentazocine
- Pentazocine,(+/-)
- Talacen
- Talwin
- US10231963, Table B.8
- US10736890, Compound TABLE B.8
- US9656961, Example 00125
- rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
|
BDBM50009307
 | 52 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | - Sigma intracellular receptor 2
- Sigma non-opioid intracellular receptor 1
- Sigma-1 receptor
- Sigma-2 receptor
| - DITOLYLGUANIDINE
- Di-o-tolylguanidine
|
BDBM50039246
 | 5 | 48 | 0 | 0 | 0 | 0 | 0 | 0 | - Betaine transporter
- GABA transporter
- GABA transporter 1
- GABA transporter 2
- GABA transporter 3
- SLC6A3
- SLC6A4
- Sodium- and chloride-dependent GABA transporter 1
| - (S)-1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)piperidine-3-carboxylic acid
- (S)-1-{2-[Tris-(4-methoxy-phenyl)-methoxy]-ethyl}-piperidine-3-carboxylic acid
- CHEMBL75035
|
BDBM50051568
 | 47 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | - Neurokinin 1 receptor
- Somatostatin receptor type 1
- Somatostatin receptor type 2
- Somatostatin receptor type 3
- Somatostatin receptor type 4
- Somatostatin receptor type 5
| - (3S,6S,9S,12R,15S,18S)-9-(4-Amino-butyl)-3-benzyl-15-(4-hydroxy-benzyl)-12-(1H-indol-3-ylmethyl)-6-isopropyl-1,18-dimethyl-1,4,7,10,13,16hexaaza-cyclooctadecane-2,5,8,11,14,17-hexaone
- CHEMBL311695
- seglitide
|
BDBM50158460
 | 4 | 44 | 1 | 4 | 0 | 0 | 0 | 0 | - 10 kDa chaperonin
- 60 kDa chaperonin
- Aldo-keto reductase family 1 member C1
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- Cytochrome P450 1A
- Cytochrome P450 2C19
- Cytochrome P450 2C9
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 2J2
- Cytochrome P450 3A
- EYA3(ED)
- Eyes absent homolog 3 (EYA3)
- Eyes absent homolog 3 (EYA3) (ED)
- HSP60/HSP10
- Inosine-5'-monophosphate dehydrogenase
- Monocarboxylate transporter 1 (MCT1)
- Monocarboxylate transporter 2
- Multidrug resistance protein 1/Multidrug resistance associated protein 1
- Multidrug resistance-associated protein 4
- PA/PB1
- Protein-tyrosine phosphatase 1B
- Protein-tyrosine phosphatase 1B (PTP1B)
- Solute carrier family 22 member 12
- Solute carrier family 22 member 6
- Sphingosine 1-phosphate receptor 1
- Thiosulfate sulfurtransferase
- Zinc aminopeptidase
- leucine aminopeptidase
- nuclear receptor corepressor 2 isoform 2
- perilipin-1
- perilipin-5
- photoreceptor-specific nuclear receptor
- streptokinase A precursor
| - (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone
- 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran
- 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone
- Benzbromarone
- CHEMBL388590
- US9725430, Compound 1
- US9856239, benzbromarone
- US9962362, Compound 1
- Uroleap (TN)
- cid_2333
|
BDBM50241107
 | 31 | 21 | 1 | 0 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 2A
- Aldehyde oxidase
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- DRD1
- DRD2
- HTR4
- Multidrug and toxin extrusion protein 1
- Multidrug and toxin extrusion protein 2
- Multidrug resistance-associated protein 4
- Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha
- Potassium voltage-gated channel subfamily H member 2
- Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Solute carrier family 22 member 2
| - 1-(3-(4-(5-chloro-2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)piperidin-1-yl)propyl)-1H-benzo[d]imidazol-2(3H)-one
- 5-Chloro-1-{1-[3-(2-hydroxy-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-2,3-dihydro-1H-benzoimidazol-2-ol
- 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(domperidone)
- 5-chloro-1-(1-(3-(2-oxo-2,3-dihydrobenzo[d]imidazol-1-yl)propyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
- 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
- 6-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one(Domperidone)
- CHEMBL219916
- DOMPERIDONE
- DOMPERIDONE5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one
- US9132134, Domperidone
|
BDBM81498
 | 47 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-HT5
- 5-HT5B
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 1B
- 5-hydroxytryptamine receptor 1B (5HT1B)
- 5-hydroxytryptamine receptor 1D
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 6
- HTR1D
- HTR1F
- HTR2B
- HTR6
- Serotonin 1 (5-HT1) receptor
- Serotonin 1B/1D receptor
- Serotonin 2 (5-HT2) receptor
- Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
| - 5-Methoxy-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole(RU-24969)
- CAS_108028
- CHEMBL18785
- NSC_108028
- RU 24969
|
BDBM81774
 | 43 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | - 5-hydroxytryptamine receptor 1A
- Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
- Bile salt export pump
- Canalicular multispecific organic anion transporter 1
- Canalicular multispecific organic anion transporter 2
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- D(4) dopamine receptor
- DRD1
- DRD2
- Dopamine D1 receptor
- Dopamine receptor
- Multidrug resistance-associated protein 4
- Myeloperoxidase
- Serotonin 1 (5-HT1) receptor
- Serotonin 2 (5-HT2) receptor
| - CAS_15676-16-1
- SULPIRIDE,(+)
- Sulpiride-S
- Sulpiride-l
|
BDBM82015
 | 43 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | - Adenosine A1 receptor
- Adenosine A2 receptor
- Adenosine A2a receptor
- Adenosine Receptors A2a (A2a)
- Adenosine receptor
- Adenosine receptor A1
- Adenosine receptor A2a
- Adenosine receptor A2b
- Adenosine receptor A3
| - 1,3-Dimethyl-8-phenyl-3,9-dihydro-purine-2,6-dione
- 8-Phenyltheophylline
- CAS_1922
- CHEMBL62350
- NSC_1922
|
Search and Browse
