Compound Name
(alphabetical) | Enz. Inhib. Data | ITC Data | Binding Targets | Alternate Compound Names |
|---|
| Ki | IC50 | Kd | EC50 | Koff | Kon | Other |
|---|
BDBM10858
 | 77 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | - Astrosclerin-3
- Beta-carbonic anhydrase
- Carbonate dehydratase
- Carbonic Anhydrase (hpCA)
- Carbonic Anhydrase IV
- Carbonic Anhydrase VA
- Carbonic Anhydrase VB
- Carbonic Anhydrase XIV
- Carbonic Anhydrase XV
- Carbonic anhydrase
- Carbonic anhydrase 1
- Carbonic anhydrase 12
- Carbonic anhydrase 2
- Carbonic anhydrase 4
- Carbonic anhydrase 6 (CA-VI)
- Carbonic anhydrase 7
- Carbonic anhydrase 9
- Carbonic anhydrase, alpha family
- Gamma-carbonic anhydrase
| - 4-hydrazinylbenzene-1-sulfonamide
- CHEMBL7204
- aromatic/heteroaromatic sulfonamide 3
- hydrazide deriv. 14
|
BDBM50017721
 | 71 | 6 | 2 | 0 | 0 | 0 | 0 | 0 | - 5-HT3A Serotonin Receptor
- 5-HT5B
- 5-hydroxytryptamine receptor 1A
- 5-hydroxytryptamine receptor 2A
- 5-hydroxytryptamine receptor 2B
- 5-hydroxytryptamine receptor 2B (5HT2B)
- 5-hydroxytryptamine receptor 2C
- 5-hydroxytryptamine receptor 2C (5HT2C)
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Cysteinyl leukotriene receptor 1
- D(1A) dopamine receptor
- D(2) dopamine receptor
- D(3) dopamine receptor
- DRD1
- Dopamine receptor
- HTR6
- HTR7
- Histamine H1 receptor
- Histamine H3 receptor
- Histamine H4 receptor
- Muscarinic acetylcholine receptor
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Muscarinic acetylcholine receptor M4
- Muscarinic acetylcholine receptor M5
- Norepinephrine transporter
- SET domain-containing protein 7/9 (Set7/9)
- SLC6A4
- Serotonin (5-HT) receptor
- Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
- Sodium channel protein type I I alpha subunit
- Sodium-dependent noradrenaline transporter
- Sodium-dependent serotonin transporter
| - 1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine
- 1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine
- 4-(5-dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine
- 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine
- 4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine
- 5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene
- CHEMBL516
- CYPROHEPTADINE
|
BDBM50117922
 | 4 | 74 | 0 | 1 | 0 | 0 | 0 | 0 | - 1,3-beta-glucan synthase component GLS2
- Cacna1b/Cacnb3
- Calcium channel (Type L)
- Calcium release-activated calcium channel
- Cytochrome P450 2D6 (2D6)
- Cytochrome P450 3A
- P-glycoprotein (P-gp)
- P-glycoprotein 1
- P-glycoprotein 1 and 3 (MDR1a/MDR1b)
- Potassium voltage-gated channel subfamily H member 2
- Sodium channel protein type 5 subunit alpha
- Sodium channel protein type 7 subunit alpha
- Sodium channel protein type 9 subunit alpha
- Twik-RElated Potassium (K+) channel 1 (TREK1)
- Voltage-dependent T-type calcium channel subunit alpha-1H
- Voltage-gated L-type calcium channel
- Voltage-gated T-type calcium channel
- Voltage-gated calcium channel
- Voltage-gated calcium channel subunit alpha Cav2.2
- Voltage-gated sodium channel
- Voltage-gated sodium channel subunit alpha Nav1.4
| - (1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl 2-methoxyacetate
- 2-{2-[3-(1H-benzoimidazol-2-yl)-propylamino]-ethyl}-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-naphthalen-2-yl ester(Mibefradil)Methoxy-acetic acid
- CHEMBL45816
- MIBEFRADIL
- Methoxy-acetic acid (1S,2S)-2-(2-{[3-(1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-naphthalen-2-yl ester
- Methoxy-acetic acid 2-(2-{[3-(1H-benzoimidazol-2-yl)-propyl]-methyl-amino}-ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-naphthalen-2-yl ester
- Mibefradil dihydrochloride
|
BDBM50396483
 | 0 | 68 | 3 | 8 | 0 | 0 | 0 | 0 | - B-RAF V600E
- B-Raf (V600E)
- B-Raf Protein Kinase
- BRAF/CRAF
- C-RAF (Y340D Y341D)
- C-Raf (Y340D/Y341D)
- Discoidin domain-containing receptor 2
- Epidermal growth factor receptor
- Epithelial discoidin domain-containing receptor 1
- Ferrochelatase R115L (FECH)
- Ferrochelatase, mitochondrial
- Heat shock factor protein 1
- Macrophage colony stimulating factor receptor
- Mixed lineage kinase 7
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Muscarinic acetylcholine receptor M3
- Pirin
- Protein cereblon/BRAF
- RAF proto-oncogene serine/threonine-protein kinase
- RAF proto-oncogene serine/threonine-protein kinase (c-RAF)
- RAF serine/threonine protein kinase
- Serine/threonine-protein kinase A-Raf
- Serine/threonine-protein kinase B-raf
- Vascular endothelial growth factor receptor 2
| - PLX-4032
- RG 7204
- Ro 5185426
- US10570155, Vemurafenib
- US9388165, Reference, Vemurafenib (PLX-4032)
- USRE47451, PLX-4032, Roche
- VEMURAFENIB
|
BDBM6309
 | 6 | 73 | 0 | 0 | 0 | 0 | 0 | 0 | - CDK2/CycE
- CDK6/CycD3
- CDK6/cyclin D1
- CDK6/cyclin D2
- CDK7/Cyclin H/MNAT1
- Cyclin-Dependent Kinase 1 (CDK1)
- Cyclin-Dependent Kinase 2 (CDK2)
- Cyclin-Dependent Kinase 4 (CDK4)
- Cyclin-Dependent Kinase 5 (CDK5)
- Cyclin-Dependent Kinase 7 (CDK7)
- Cyclin-Dependent Kinase 9 (CDK9)
- Cyclin-K
- Cyclin-dependent kinase 1
- Cyclin-dependent kinase 2
- Cyclin-dependent kinase 4
- Cyclin-dependent kinase 6
- Cyclin-dependent kinase 7
- Cyclin-dependent kinase 9
- Cyclin-dependent-like kinase 5
- Macrophage colony stimulating factor receptor
- NUAK family SNF1-like kinase 1
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Tyrosine-protein kinase ABL1
- Tyrosine-protein kinase JAK3
- Tyrosine-protein kinase receptor FLT3
| - 6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one Hydrochloride
- 8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one
- Ibrance
- PD 0332991
- Palbociclib
- Pyrido-[2,3-d]-pyrimidin-7-one 43
- US10189849, PD0332991
- US10464927, Compound Palbociclib
- US10696682, Compound PD0332991
- US10927120, PD0332991
- US9464092, PD0332991
- US9957276, PD0332991
|
BDBM81982
 | 61 | 15 | 3 | 0 | 0 | 0 | 0 | 0 | - 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase
- Anti-estrogen binding site (AEBS)
- C-8 sterol isomerase
- HTR3A
- Human immunodeficiency virus type 1 REV
- Imidazoline I1
- Muscarinic acetylcholine receptor M1
- Muscarinic acetylcholine receptor M2
- Sigma non-opioid intracellular receptor 1
- Vesicular acetylcholine transporter
- defective in Germ Line Development family member (gld-1)
| - CAS_97-39-2
- DITOLYLGUANIDINE
- DTG
- Di-o-tolylguanidine
- Tol2Gdn
- cid_7333
|
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