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Compound Name:

Compounds Sorted by Binding Data per Compound

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55
56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81
82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105
106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124
125 127 128 129 130 132 133 134 135 136 137 138 139 140 141 143 144 145 146
147 148 149 150 151 153 154 155 156 159 160 161 163 164 165 168 170 171 173
174 176 178 179 183 184 186 188 189 190 191 192 193 196 198 199 200 203 204
205 206 207 208 209 210 216 220 224 226 227 229 232 237 238 241 243 248 252
253 259 261 270 274 276 277 285 291 303 304 313 318 323 325 328 333 335 337
339 341 353 360 361 365 389 393 398 401 413 433 442 444 445 446 447 448 451
453 454 455 457 458 460 463 465 467 473 477 478 482 484 499 504 505 506 517
521 525 543 549 551 554 591 606 663 691 708 796 804 821 825 833 842 847 854
855 861 873 879 883 887 913 914 925 926 938 947 1010 1027 1050 1052 1081 1082
1099 1115 1130 1133 1206 1262 1543 1639 1903 2029
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Enz. Inhib. Data
ITC Data
Binding Targets
Alternate Compound Names
9 IC50
  • Carbonic anhydrase 2
  • Cytochrome P450 19A1
  • Steryl-sulfatase
  • (4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate
  • JMC503540 Compound 2
  • YM511 Analog 4
  • YM511-based dual aromatase-sulfatase inhibitor (DASI) 4
  • dual aromatase-sulfatase inhibitor 4
9 IC50
  • Carbonic anhydrase 2
  • Cytochrome P450 19A1
  • Steryl-sulfatase
  • (2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate
  • JMC503540 Compound 5
  • YM511 Analog 5
  • YM511-based dual aromatase-sulfatase inhibitor (DASI) 7
  • dual aromatase-sulfatase inhibitor 7
8 Ki 1 IC50
  • Caspase-1
  • Caspase-2
  • Caspase-3
  • Caspase-4
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • Caspase-9
  • 1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione
  • Isatin analog 1
8 Ki 1 IC50
  • Caspase-1
  • Caspase-2
  • Caspase-3
  • Caspase-4
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • Caspase-9
  • 1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione
  • Isatin analog 2
6 Ki 3 IC50
  • Acetylcholinesterase
  • Acyl-CoA: cholesterol acyltransferase (ACAT)
  • Carboxylesterase 1
  • Caspase-3
  • Cholinesterases
  • Chorismate mutase (MTB CM)
  • Factor XIIa
  • Human rhinovirus A protease
  • Transthyretin
  • 1-methyl-2,3-dihydro-1H-indole-2,3-dione
  • CHEMBL60569
  • Isatin analog 8
  • N‐methylindol‐2,3‐dione (Compound 2)
8 Ki 1 IC50
  • Caspase-1
  • Caspase-2
  • Caspase-3
  • Caspase-4
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • Caspase-9
  • (R)-5-{1-[2-(Anilinomethyl)pyrrolidinyl]sulfonyl}isatin
  • 5-{[(2R)-2-[(phenylamino)methyl]pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione
  • Isatin Sulfonamide 27
1 Ki 6 IC50 1 EC50
0 ΔG°
  • Caspase-1
  • Caspase-3
  • Caspase-6
  • Caspase-7
  • Caspase-8
  • 5-(2-(Pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione
  • 5-{[(2S)-2-[(pyridin-3-yloxy)methyl]pyrrolidine-1-]sulfonyl}-2,3-dihydro-1H-indole-2,3-dione
  • IST-1
  • Pyridine Analogue 20
9 IC50
  • Cereblon/Histone deacetylase 1
  • Histone deacetylase 1
  • Histone deacetylase 8
  • CHEMBL474152
  • US10201527, Compound 40
  • US10736881, Compound 14
  • US8551988, 14
6 Ki 3 EC50
  • Beta-2 adrenergic receptor
  • Muscarinic acetylcholine receptor M3
  • US8551978, I-46
  • US8816088, I-46
  • US9394275, I-46
  • US9572802, Compound I-46
  • US9682957, I-46
9 IC50
  • Serine/threonine-protein kinase PIM-3
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • US8575145, 157
  • US8575145, 158
  • US8575145, 52/127/128
9 IC50
  • 5-hydroxytryptamine 1D receptor (5HT1D)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
  • Serotonin 1B/1D receptor
  • CHEMBL1957349
  • US8586620, 42
9 IC50
  • 11-beta-hydroxysteroid dehydrogenase
  • 11-beta-hydroxysteroid dehydrogenase 1
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 3A
  • US8575157, 30
9 IC50
  • Egl nine homolog 1
  • Prolyl hydroxylase EGLN3
  • US10889546, US2007/0299086 Table 2.4
  • US8598210, Table XV, 9
  • US8722895, 9: {[5-(4-Chlorophenyl)-3-hydroxypyridine-2- carbonyl]amino}-acetic acid
  • US9598370, Example 00134
  • USRE47437, Example {[5-(4-Chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}-acetic acid
9 Ki
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1r subcomponent
  • Complement C1s
  • Plasma kallikrein
  • Plasminogen
  • Transcription initiation factor IIA
  • Vitamin K-dependent protein C
  • US8598206, Table 6, 4
9 Ki
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1r subcomponent
  • Complement C1s
  • Plasma kallikrein
  • Plasminogen
  • Transcription initiation factor IIA
  • Vitamin K-dependent protein C
  • US8598206, Table 6, 6
9 Ki
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1r subcomponent
  • Complement C1s
  • Plasma kallikrein
  • Plasminogen
  • Transcription initiation factor IIA
  • Vitamin K-dependent protein C
  • US8598206, Table 6, 21
9 IC50
  • Casein Kinase I
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • Glycogen Synthase Kinase-3, beta
  • cAMP-Dependent Protein Kinase (PKA)
  • cGMP-Dependent Protein Kinase
  • 4-(6-bromo-1H-indol-3-yl)pyrimidin-2-amine
  • Meridianin D
9 IC50
  • Glutaminase kidney isoform, mitochondrial
  • Glutaminase liver isoform, mitochondrial
  • US8604016, 21
  • US9938267, Cmpd ID 21
9 IC50
  • Acetylcholinesterase
  • Butyrylcholinesterase
  • Cholinesterases
  • (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-[4-(propan-2-yl)phenyl]carbamate
  • 4-isopropylphenserine
  • Cymserine
  • cymserine.tartaric acid
9 IC50
  • Acetylcholinesterase
  • Cholinesterases
  • (3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N,N-dimethylcarbamate
  • CHEMBL308043
  • N-methylphysostigmine
  • Physostigmine analog 33
9 IC50
  • JAK3/JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • US8609647, 1
  • US8609647, 15
  • US8609647, 2
  • US8609647, 23
9 Ki
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Monoamine Oxidase Type B (MAO-B)
  • Monoamine oxidase type B (MAO-B) Mutant (I199F)
  • 2-[(E)-2-(3-chlorophenyl)ethenyl]-3,5,7-trimethyl-3H,4H,5H,6H,7H-imidazo[4,5-c]pyridine-4,6-dione
  • 8-(3-chlorostyryl)caffeine (CSC)
9 Ki
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Monoamine Oxidase Type B (MAO-B)
  • Monoamine oxidase type B (MAO-B) Mutant (I199F)
  • 1,4-diphenyl-2-butene (DPB)
  • [(2E)-4-phenylbut-2-en-1-yl]benzene
7 IC50 2 EC50
  • Serine/threonine-protein kinase/endoribonuclease IRE1 Alpha
  • US8614253, 3-14
  • US8614253, 42-12
  • US8614253, 43-5
  • US9241942, 3-14
  • US9963434, Compound 3-14
8 IC50 1 EC50
  • Serine/threonine-protein kinase/endoribonuclease IRE1 Alpha
  • US8614253, 3-67
  • US8614253, 3-74
  • US8614253, 43-83
  • US9241942, 3-67
  • US9963434, Compound 3-74
9 IC50
  • Dipeptidyl peptidase 2 (DPP II)
  • Dipeptidyl peptidase 4
  • Dipeptidyl peptidase 9
  • Dipeptidyl peptidase VIII
  • (3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[3,4-a]pyrazin-7-yl]butan-1-one hydrochloride
  • Sitagliptin Analog 13
  • Triazolopiperazine Analogue 25
9 IC50
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
  • Interstitial collagenase
  • Matrix metalloproteinase-9
  • Stromelysin-1
  • US8633196, 14
  • US8633196, 5
  • US9365529, 5
8 Ki 1 IC50
  • 72 kDa type IV collagenase
  • Aldehyde dehydrogenase 1A1
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Interstitial collagenase
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • CHEMBL98328
  • Hydroxysulfonamide 46
  • N-hydroxymethanesulfonamide
8 Ki 1 IC50
  • 72 kDa type IV collagenase
  • Aldehyde dehydrogenase 1A1
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Interstitial collagenase
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • CHEMBL55310
  • Hydroxysulfonamide 53
  • N-hydroxybenzenesulfonamide
9 IC50
  • Beta-secretase 1
  • Beta-secretase 2
  • IDH1 R132H
  • US10035794, Example 10
  • US10683287, Example 10
  • US8637508, 10
9 IC50
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • US8653092, 81
9 IC50
  • MurA (E. coli)
  • MurB (E. coli)
  • MurB (S. aureus)
  • MurC
  • MurC (S. aureus)
  • MurD
  • MurD (S. aureus)
  • MurE
  • MurE (E. coli)
  • MurA/B/C/D/E inhibitor (compound 67)
9 IC50
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Macrophage colony-stimulating factor 1 receptor (c-Fms)
  • Mast/stem cell growth factor receptor Kit
  • Potassium voltage-gated channel subfamily H member 2
  • CHEMBL256712
  • US8697716, 16
9 IC50
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor beta
  • Tyrosine-protein kinase ABL1
  • US8703771, 13
  • US8703771, 14
  • US8703771, 8
4 Ki 5 IC50
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US8710076, E-2
9 IC50
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • US8722890, 3
9 IC50
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • US8722890, 4
9 IC50
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • US8722890, 5
9 IC50
  • 1,3-beta-glucan synthase component GLS2
  • G-protein coupled receptor 4
  • G-protein coupled receptor 4 (GPR4)
  • Histamine H3 receptor
  • Ovarian cancer G-protein coupled receptor 1
  • Psychosine receptor
  • US8748435, 35
9 IC50
  • 1,3-beta-glucan synthase component GLS2
  • G-protein coupled receptor 4
  • G-protein coupled receptor 4 (GPR4)
  • Histamine H3 receptor
  • Melanin-concentrating hormone receptor 2/HERG
  • US8748435, 40
7 IC50 2 EC50
  • Phospholipase D (PLD)
  • Phospholipase D (PLD_sp)
  • Phospholipase D2 (PLD2)
  • 5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)ethyl)-1H-indole-2-carboxamide, 14
  • CHEMBL398567
  • FIPI hydrochloride hydrate (FIPI_HCl)
9 IC50
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Cereblon/BCR/ABL
  • Phospholipase D (PLD)
  • Phospholipase D (PLD_SC)
  • Phospholipase D (PLD_sp)
  • Phospholipase D2 (PLD2)
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase ABL1
  • 1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (5)
  • 1-tert-butyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (5)
  • CHEMBL2069938
  • US10544104, Compound 140
  • US9765037, Compound 140
3 IC50 6 Kd
  • Cytochrome P450 2B6
  • Cytochrome P450 2D6
  • Poly [ADP-ribose] polymerase 1
  • Poly [ADP-ribose] polymerase 2
  • Poly [ADP-ribose] polymerase tankyrase-1
  • Protein mono-ADP-ribosyltransferase PARP3
  • US8765972, 4
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 139
  • US9682141, 217
9 IC50
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 33
  • Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
  • Interstitial collagenase
  • Matrix metalloproteinase-9
  • Stromelysin-1
  • US8772478, 15
  • US8772478, 8
6 Ki 3 IC50
  • 5-hydroxytryptamine receptor 1A
  • Cytochrome P450 2D6 (2D6)
  • Sodium-dependent serotonin transporter
  • US8778970, 5-1
  • US8778970, 5-12
  • US8778970, 5-13
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 169
  • US9682141, 252
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 170
  • US9682141, 253
9 Ki
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • 4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
  • CHEMBL387076
  • Glycoconjugate Benzene Sulfonamide 2a
  • [(2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4-{[(4-sulfamoylphenyl)formamido]methyl}-1H-1,2,3-triazol-1-yl)oxan-2-yl]methyl acetate
9 Ki
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • 4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole
  • 4-sulfamoyl-N-({1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)benzamide
  • CHEMBL385152
  • Glycoconjugate Benzene Sulfonamide 2aa
9 Ki
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • 4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
  • CHEMBL383897
  • Glycoconjugate Benzene Sulfonamide 3a
  • {1-[(2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-[(acetyloxy)methyl]oxan-2-yl]-1H-1,2,3-triazol-4-yl}methyl 4-sulfamoylbenzoate
9 Ki
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • 4-({[4-(Aminosulfonyl)benzoyl]oxy}methyl-1-(beta-D-glucopyranosyl)-1H-1,2,3-triazole
  • CHEMBL425274
  • Glycoconjugate Benzene Sulfonamide 3aa
  • {1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-1H-1,2,3-triazol-4-yl}methyl 4-sulfamoylbenzoate
9 Ki
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Vitamin K-dependent protein C
  • 4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfonylamino)-2-oxopyrrolidin-1-ylmethyl]benzamidine
  • 4-hydroxy-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide
  • CHEMBL93854
  • Sulfonamidopyrrolidinone 20a
9 Ki
  • Coagulation factor VII
  • Coagulation factor X
  • Prothrombin
  • Trypsin
  • 2-[(4-carbamimidoylphenyl)amino]-2-(3,5-diethoxyphenyl)acetic acid
  • phenylglycine deriv. 6
  • phenylglycine derivative 1
9 Ki
  • Coagulation factor X
  • Prothrombin
  • Trypsin
  • Trypsin-1
  • Urokinase-type plasminogen activator
  • 2-(2-HYDROXY-5-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE
  • APC-6669
  • {amino[2-(2-hydroxy-5-methoxyphenyl)-1H-1,3-benzodiazol-5-yl]methylidene}azanium
9 IC50
  • Cyclin-dependent kinase 2
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Rho-associated protein kinase 1
  • Rho-associated protein kinase 2
  • Ribosomal protein S6 kinase (P70S6K)
  • Ribosomal protein S6 kinase alpha 5
  • 4-(1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine
  • 4-{1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl}-1,2,5-oxadiazol-3-amine
  • Aminofurazanyl-azabenzimidazole 1
  • CHEMBL189657
9 Ki
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Vitamin K-dependent protein C
  • 4-hydroxy-3-[[(3S)-2-oxo-3-(9-thia-5-azabicyclo[4.3.0]nona-2,4,7,10-tetraen-8-ylsulfonylamino)pyrrolidin-1-yl]methyl]benzenecarboximidamide
  • 4-hydroxy-3-{[(3S)-2-oxo-3-{thieno[3,2-b]pyridine-2-sulfonamido}pyrrolidin-1-yl]methyl}benzene-1-carboximidamide
  • CHEMBL330572
  • RPR131247
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 548
  • US9682141, 552
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 562
  • US9682141, 566
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 570
  • US9682141, 571
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 590
  • US9682141, 597
9 IC50
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • US9682141, 601
  • US9682141, 606
9 IC50
  • Tyrosine-protein kinase SYK
  • US8969568, 103
  • US8969568, 104
  • US8969568, 105
  • US8969568, 106
  • US8969568, 109
  • US8969568, 110
  • US8969568, 114
  • US8969568, 116
  • US8969568, 57
9 Ki
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin-1
  • Tryptase
  • Urokinase (uPA) Mutant (S190A)
  • Urokinase-type plasminogen activator
  • CA-21
  • [amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-2-yl}amino)methylidene]azanium
9 Ki
  • Coagulation factor X
  • Hepsin
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin-1
  • Urokinase (uPA) Mutant (S190A)
  • Urokinase-type plasminogen activator
  • 2-amino-5-[(3-hydroxynaphthalene-2-)amido]-1H-1,3-benzodiazol-3-ium
  • CA-24
9 IC50
  • Sodium channel alpha subunit
  • Sodium channel protein type 2 alpha subunit
  • Sodium channel protein type 5 subunit alpha
  • Sodium channel protein type 7 subunit alpha
  • Sodium channel protein type 8 subunit alpha
  • Sodium channel protein type 9 subunit alpha
  • Voltage-gated sodium channel
  • US8952169, 389
9 IC50
  • Coagulation factor III/Factor VIIa (fVIIa)
  • Coagulation factor VII
  • Coagulation factor X
  • Prothrombin
  • Trypsin-1
  • 3-amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}methyl)-3-chloro-6-oxo-5-(propan-2-ylamino)-1,6-dihydropyrazin-2-yl]benzoic acid
  • CHEMBL77076
  • Pyrazinone Analog 34
1 Ki 6 IC50 2 Kd
  • 3-dehydroquinate dehydratase
  • Alpha-ketoglutarate-dependent dioxygenase FTO
  • Beta-lactamase
  • Hepatocyte nuclear factor 4-alpha
  • Prolyl 4-hydroxylase
  • Proto-oncogene tyrosine-protein kinase Src (aa 145-252)
  • perilipin-1
  • perilipin-5
  • 2-hydroxypropane-1,2,3-tricarboxylic acid
  • CHEMBL1261
  • CITRIC ACID
  • Citrate
  • Citric Acid
  • Fragment 2
  • cid_311
2 Ki 7 IC50
  • Dihydroorotate Dehydrogenase (DHODH)
  • Dihydroorotate Dehydrogenase (DHODH) Mutant (H185A)
  • Dihydroorotate Dehydrogenase (DHODH) Mutant (R265A)
  • Dihydroorotate dehydrogenase
  • Dihydroorotate dehydrogenase (quinone), mitochondrial
  • Asinex compound no. 6
  • N-(3,5-Dichlorophenyl)-2-methyl-3-nitrobenzamide
  • benzamide compound 3
8 IC50 1 Kd
  • Arachidonate 5-lipoxygenase
  • MAP kinase p38
  • Mitogen-activated protein kinase 14
  • Prostaglandin G/H synthase (cyclooxygenase)
  • 3-(4-fluorophenyl)-2-pyridin-4-yl-6-thia-1,4-diazabicyclo[3.3.0]octa-2,4-diene
  • 4-[6-(4-fluorophenyl)-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl]pyridine
  • CHEMBL313417
  • SKF 86002
9 IC50
  • Beta-secretase 1
  • Potassium voltage-gated channel subfamily H member 2
  • US8975415, RP16a
  • US8975415, RP16b
  • US9242973, RP16b
9 IC50
  • Beta-secretase 1
  • Potassium voltage-gated channel subfamily H member 2
  • US8975415, RP88
  • US8975415, RP89
  • US9242973, RP89
9 IC50
  • Beta-secretase 1
  • Potassium voltage-gated channel subfamily H member 2
  • US8975415, RP97
  • US8975415, RP98
  • US9242973, RP98
2 Ki 7 IC50
  • Beta-secretase 1
  • Potassium voltage-gated channel subfamily H member 2
  • US8975415, 219
  • US9242973, 219
9 IC50
  • Androgen Receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 2
  • Mineralocorticoid receptor
  • Multidrug resistance-associated protein 4
  • Progesterone receptor
  • US8987239, A
  • US9034856, A
9 IC50
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Leukocyte common antigen
  • Protein-tyrosine phosphatase
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Tyrosine-protein phosphatase non-receptor type 11
  • US8987474, NSC-87877
9 Ki
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • 4-(4-{[(2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)oxy]methyl}-1H-1,2,3-triazol-1-yl)benzenesulfonamide
  • CHEMBL374275
  • [(2R,3R,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-{[1-(4-sulfamoylphenyl)-1H-1,2,3-triazol-4-yl]methoxy}oxan-2-yl]methyl acetate
  • glycoconjugate sulfonamide 7
8 Ki 1 Kd
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase (bsNOS)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
  • 4-methyl-6-[2-(3-{methyl[2-(methylamino)ethyl]amino}phenyl)ethyl]pyridin-2-amine (13)
  • US9951014, Name 10a
8 Ki 1 Kd
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase (bsNOS)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
  • 4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amino}pyridin-2-yl)ethyl]pyridin-2-amine (15)
  • US9951014, Name 14a
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 1
  • US9000015, 1
  • US9610299, Example 1
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 2
  • US9000015, 2
  • US9610299, Example 2
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 3
  • US9000015, 3
  • US9610299, Example 3
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 8
  • US9000015, 8
  • US9610299, Example 8
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 9
  • US9000015, 9
  • US9610299, Example 9
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 10
  • US9000015, 10
  • US9610299, Example 10
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 11
  • US9000015, 11
  • US9610299, Example 11
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 12
  • US9000015, 12
  • US9610299, Example 12
9 IC50
  • Aldehyde dehydrogenase, mitochondrial
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] A
  • Amine oxidase [flavin-containing] B
  • US10507215, Compound 13
  • US9000015, 13
  • US9610299, Example 13
5 IC50 4 EC50
  • Heat shock protein HSP 90-alpha
  • Heat shock protein HSP 90-beta
  • 3-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
  • CHEMBL365617
  • Compound 11
  • N-Ethyl-3-(5-Chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
  • VER-49009
9 IC50
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 2
  • Serine/threonine-protein kinase TBK1
  • Oxindole (Scaffold V)
9 IC50
  • Chromobox protein homolog 7 (CBX7)
  • E3 ubiquitin-protein ligase (UHRF1)
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lysine-specific demethylase 5A
  • MBT domain-containing protein 1 (MBTD1)
  • Methyl-lysine binding protein (53BP1)
  • PHD finger protein 1 (PHF1)
  • PHD finger protein 19 (PHF19)
  • PHD finger protein 23 (PHF23)
  • 3-Bromo-N-(3-(dimethylamino)propyl)benzamide (2)
9 IC50
  • Chromobox protein homolog 7 (CBX7)
  • E3 ubiquitin-protein ligase (UHRF1)
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lysine-specific demethylase 5A
  • MBT domain-containing protein 1 (MBTD1)
  • Methyl-lysine binding protein (53BP1)
  • PHD finger protein 1 (PHF1)
  • PHD finger protein 19 (PHF19)
  • PHD finger protein 23 (PHF23)
  • 3-Bromo-N-(3-(isopropylamino)propyl)benzamide (3)
9 IC50
  • Chromobox protein homolog 7 (CBX7)
  • E3 ubiquitin-protein ligase (UHRF1)
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lysine-specific demethylase 5A
  • MBT domain-containing protein 1 (MBTD1)
  • Methyl-lysine binding protein (53BP1)
  • PHD finger protein 1 (PHF1)
  • PHD finger protein 19 (PHF19)
  • PHD finger protein 23 (PHF23)
  • 3-Bromo-N-(3-(tert-butyl(methyl)amino)propyl)benzamide (UNC2892, 4)
9 IC50
  • Chromobox protein homolog 7 (CBX7)
  • E3 ubiquitin-protein ligase (UHRF1)
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lysine-specific demethylase 5A
  • MBT domain-containing protein 1 (MBTD1)
  • Methyl-lysine binding protein (53BP1)
  • PHD finger protein 1 (PHF1)
  • PHD finger protein 19 (PHF19)
  • PHD finger protein 23 (PHF23)
  • 3-Bromo-N-(3-(tert-butoxy)propyl)benzamide (5)
9 IC50
  • Chromobox protein homolog 7 (CBX7)
  • E3 ubiquitin-protein ligase (UHRF1)
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lysine-specific demethylase 5A
  • MBT domain-containing protein 1 (MBTD1)
  • Methyl-lysine binding protein (53BP1)
  • PHD finger protein 1 (PHF1)
  • PHD finger protein 19 (PHF19)
  • PHD finger protein 23 (PHF23)
  • 3-Bromo-N-(3-(pyrrolidin-1-yl)propyl)benzamide (6)
2 Ki 7 IC50
  • Cytochrome P450 3A
  • Orexin receptor type 1
  • Orexin receptor type 2
  • US9000029, 26
9 IC50
  • HIV-1 Reverse Transcriptase
  • HIV-1 Reverse Transcriptase Mutant (G190A)
  • HIV-1 Reverse Transcriptase Mutant (K103N)
  • HIV-1 Reverse Transcriptase Mutant (P236L)
  • HIV-1 Reverse Transcriptase Mutant (V106A)
  • HIV-1 Reverse Transcriptase Mutant (Y181C)
  • HIV-1 Reverse Transcriptase Mutant (Y188L)
  • 2-ethyl-9-methyl-5-(1H-pyrrol-3-yl)-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
  • Dipyridodiazepinone deriv. 42
  • dipyridodiazepinone 2
9 IC50
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • US9034899, 2
  • US9034899, 3
  • US9604960, 3
9 IC50
  • JAK1/TYK2
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • US9035074, 1
9 IC50
  • JAK1/TYK2
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • US9035074, 3
9 IC50
  • JAK1/TYK2
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • US9035074, 6
9 IC50
  • JAK1/TYK2
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • US9035074, 14
9 IC50
  • JAK1/TYK2
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • US9035074, 22
8 IC50 1 Kd
  • Complement factor B
  • Complement factor D
  • US10093663, Example 26b
  • US9682968, Example-26a
9 IC50
  • Beta-secretase 1
  • Beta-secretase 2
  • Cathepsin D
  • Cytochrome P450 2D6
  • Melanin-concentrating hormone receptor 2/HERG
  • US9045498, 8
9 IC50
  • Cereblon/Histone deacetylase 6
  • Histone deacetylase 1
  • Histone deacetylase 4
  • US9056843, 80
  • US9056843, 86
  • US9056843, 87
9 IC50
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 7
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 10 (PDE10A)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase B
  • US9056863, Example Ic1
5 Ki 4 IC50
  • Enoyl-ACP Reductase (FabI)
  • Enoyl-ACP Reductase (InhA)
  • Enoyl-ACP reductase (Wt ypFabV)
  • Enoyl-ACP reductase T276S (T276S ypFabV)
  • Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)
  • 5-Octyl-2-phenoxy-phenol
  • 5-heptyl-2-phenoxylphenol
  • 5-octyl-2-phenoxyphenol
  • 8PP
  • AIDS227448
  • CHEMBL505886
  • PT05
9 IC50
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 2
  • HDAC1/NCOR2
  • HDAC2/NCOR2
  • HDAC3/NCOR2
  • Histone deacetylase 3
  • SR-3203
  • US10807944, Compound RLS2-306
9 Ki
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US9062078, 77
  • US9637496, 77
  • US9695183, 77
9 Ki
  • Orexin receptor type 1
  • Orexin receptor type 1 (OX1)
  • Orexin receptor type 2
  • US9062078, 134
  • US9475819, 134
  • US9637496, 134
  • US9695183, 134
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-2-1
  • US9067914, Ex. 3-2-1
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-2-2
  • US9067914, Ex. 3-2-2
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-2-3
  • US9067914, Ex. 3-2-3
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-3
  • US9067914, Ex. 3-3
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-4
  • US9067914, Ex. 3-4
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-5
  • US9067914, Ex. 3-5
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-6
  • US9067914, Ex. 3-6
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-7
  • US9067914, Ex. 3-7
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-8
  • US9067914, Ex. 3-8
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-9
  • US9067914, Ex. 3-9
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-10
  • US9067914, Ex. 3-10
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-11
  • US9067914, Ex. 3-11
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-12
  • US9067914, Ex. 3-12
9 IC50
  • BDNF/NT-3 growth factors receptor
  • High affinity nerve growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • US10166239, Ex. 3-13
  • US9067914, Ex. 3-13
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