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34 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo.EBI
Novartis Pharma
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors.EBI
Novartis Institutes For Biomedical Research
Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.EBI
University Of Michigan
Inhibitors of factor d may provide a treatment for age-related macular degeneration.EBI
Therachem Research Medilab (India)
Factor D Inhibitors for the Treatment of AMD: Patent Highlight.EBI
TBA
Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach.EBI
Novartis Institutes For Biomedical Research
Discovery of 4-((2 S,4 S)-4-Ethoxy-1-((5-methoxy-7-methyl-1 H-indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated DiseasesEBI
Novartis Institutes For Biomedical Research
Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway.EBI
Novartis Institutes For Biomedical Research
Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects.EBI
Lavis
Chemical Approaches to Modulating Complement-Mediated Diseases.EBI
The University Of Queensland
Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D.EBI
Novartis Pharma
1H-1,2,4-triazol-3-yl-anilines: novel potent inhibitors of vascular endothelial growth factor receptors 1 and 2.BDB
Chemdiv
In silico screening for non-nucleoside HIV-1 reverse transcriptase inhibitors using physicochemical filters and high-throughput docking followed by in vitro evaluation.BDB
University Of Jordan
 
Thermodynamic and Nuclear Magnetic Resonance Study of the Interactions of alpha-and beta-Cyclodextrin with Model Substances: Phenethylamine, Ephedrines, and Related SubstancesBDB
Nist
Novel flufenamic acid analogues as inhibitors of androgen receptor mediated transcription.BDB
St. Jude Research Hospital
Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides.BDB
Amgen
Tyrosine kinase inhibitors. 7. 7-Amino-4-(phenylamino)- and 7-amino-4-[(phenylmethyl)amino]pyrido[4,3-d]pyrimidines: a new class of inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor.BDB
University Of Auckland
Design and fast synthesis of C-terminal duplicated potent C(2)-symmetric P1/P1'-modified HIV-1 protease inhibitors.BDB
Uppsala University