50 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Quinoxaline N-oxide containing potent angiotensin II receptor antagonists: synthesis, biological properties, and structure-activity relationships.
Bristol-Myers Squibb Pharmaceutical Research Institute
Nonpeptide angiotensin II receptor antagonists. 2. Design, synthesis, and structure-activity relationships of 2-alkyl-4-(1H-pyrrol-1-yl)-1H-imidazole derivatives: profile of 2-propyl-1-[[2'-(1H-tetrazol-5-yl)-[1,1' -biphenyl]-4-yl]-methyl]-4-[2-(trifluoroacetyl)-1H-pyrrol-1-yl]-1H- imidazole-5-car
Warner-Lambert
Potent nonpeptide angiotensin II receptor antagonists. 2. 1-(Carboxybenzyl)imidazole-5-acrylic acids.
Smithkline Beecham Pharmaceuticals
Conformationally restricted polysubstituted biphenyl derivatives with angiotensin II receptors antagonist properties.
Searle R & D And Mcr
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives.
E. I. Du Pont De Nemours
Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype.
Warner-Lambert
Nonpeptide angiotensin II receptor antagonists: N-[(benzyloxy)benzyl]imidazoles and related compounds as potent antihypertensives.
E. I. Du Pont De Nemours And
The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives.
E. I. Du Pont De Nemours
Topographic probes of angiotensin and receptor: potent angiotensin II agonist containing diphenylalanine and long-acting antagonists containing biphenylalanine and 2-indan amino acid in position 8.
Washington State University
Synthesis and evaluation of novel angiotensin II receptor 1 antagonists as anti-hypertension drugs.
Donghua University
Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands.
Uppsala University
Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome.
The University Of Mississippi
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems.
Universit£
2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists.
Abbott Laboratories
4,5-Dihydro-4-oxo-3H-imidazo[4,5-c]pyridines: potent arylacetic acid-derived AT1 antagonists with improved affinity for the AT2 receptor
TBA
Balanced AT1 and AT2 angiotensin II antagonists. II. Potent 5 α-hydroxyacid imidazolyl biphenyl sulfonylureas
TBA
The SAR of 6-(N-alkyl-N-acyl)-2-propyl-3-[(2′-tetrazol-5-yl)biphen-4-yl)methyl]-quinazolinones as balanced affinity antagonists of the human AT1 and AT2 receptors
TBA
Potent triazolinone-based angiotensin II receptor antagonists with equivalent affinity for both the AT1 and AT2 subtypes
TBA
Development of angiotensin II antagonists with equipotent affinity for human AT1 and AT2 receptor subtypes.
TBA
Balanced angiotensin II receptor antagonists. I. The effects of biphenyl “ortho”-substitution on AT1/AT2 affinities
TBA
Synthesis and biological evaluation of the potent isoxazolidinyl angiotensin II receptor antagonist CL332,877 and its enantiomers.
TBA
6-isoxazolinyl and isoxazolidinyl substituted quinazolinones as angiotensin II receptor antagonists
TBA
Selective angiotensin II AT2 receptor agonists: Benzamide structure-activity relationships.
Uppsala University
Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system.
Uppsala University
Discovery of 4'-[(imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/angiotensin II receptor antagonists.
Bristol-Myers Squibb Pharmaceutical Research Institute
Specific nonpeptide photoprobes as tools for the structural study of the angiotensin II AT(1) receptor.
Laboratoires Fournier
Multiple binding modes for the receptor-bound conformations of cyclic AII agonists.
Washington University
A novel series of selective, non-peptide inhibitors of angiotensin II binding to the AT2 site.
Dupont Pharmaceuticals
Conformational restriction of angiotensin II: cyclic analogues having high potency.
G.D. Searle And
Imidazole-5-acrylic acids: potent nonpeptide angiotensin II receptor antagonists designed using a novel peptide pharmacophore model.
Smithkline Beecham Pharmaceuticals