The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

10 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Highly Potent and Isoform Selective Dual Site Binding Tankyrase/Wnt Signaling Inhibitors That Increase Cellular Glucose Uptake and Have Antiproliferative Activity.EBI
University Of Bath
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.EBI
Health & Science University
Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor.EBI
University Of Oslo
Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515.EBI
Nerviano Medical Sciences
Discovery and Optimization of 2-Arylquinazolin-4-ones into a Potent and Selective Tankyrase Inhibitor Modulating Wnt Pathway Activity.EBI
Merck Healthcare
Rational Design of Cell-Active Inhibitors of PARP10.EBI
Oregon Health And Science University
Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering.EBI
Astrazeneca
4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10.EBI
University Of Oulu
Discovery of a Novel Series of Tankyrase Inhibitors by a Hybridization Approach.EBI
Leibniz-Forschungsinstitut F�R Molekulare Pharmakologie (Fmp)