PMID

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Article Title

Organization

Recent advances in the chemistry and biology of pyridopyrimidines.

Universit£

Structural basis for inhibition of mycobacterial and human adenosine kinase by 7-substituted 7-(Het)aryl-7-deazaadenine ribonucleosides.

Academy Of Sciences Of The Czech Republic

A TOPS-MODE approach to predict adenosine kinase inhibition.

Vigo University

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

University Of Oxford

Fragment-based drug discovery.

Sunesis Pharmaceuticals

New adenosine kinase inhibitors with oral antiinflammatory activity: synthesis and biological evaluation.

University Of California

Synthesis, intramolecular hydrogen bonding, and biochemical studies of clitocine, a naturally occurring exocyclic amino nucleoside.

Nucleic Acid Research Institute

Synthesis and significant cytostatic activity of 7-hetaryl-7-deazaadenosines.

Academy Of Sciences Of The Czech Republic

Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.

Universita` Di Siena

Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.

Metabasis Therapeutics

Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics.

Metabasis Therapeutics

4-amino-5-aryl-6-arylethynylpyrimidines: structure-activity relationships of non-nucleoside adenosine kinase inhibitors.

Abbott Laboratories

Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds.

Metabasis Therapeutics

Adenosine kinase inhibitors. 5. Synthesis, enzyme inhibition, and analgesic activity of diaryl-erythro-furanosyltubercidin analogues.

Metabasis Therapeutics

Synthesis and biological evaluation of 6,7-disubstituted 4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors.

Abbott Laboratories

Adenosine kinase inhibitors. 4. 6,8-Disubstituted purine nucleoside derivatives. Synthesis, conformation, and enzyme inhibition.

Metabasis Therapeutics

Synthesis and biological evaluation of pteridine and pyrazolopyrimidine based adenosine kinase inhibitors.

Abbott Laboratories

Discovery and optimization of 2-aryl oxazolo-pyrimidines as adenosine kinase inhibitors using liquid phase parallel synthesis.

Bayer

5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel inhibitors of adenosine kinase.

Abbott Laboratories

Adenosine kinase inhibitors. 3. Synthesis, SAR, and antiinflammatory activity of a series of l-lyxofuranosyl nucleosides.

Metabasis Therapeutics

Adenosine kinase inhibitors: polar 7-substitutent of pyridopyrimidine derivatives improving their locomotor selectivity.

Abbott Laboratories

QSAR study on adenosine kinase inhibition of pyrrolo[2,3-d]pyrimidine nucleoside analogues using the hansch approach.

Jadavpur University

Pyridopyrimidine analogues as novel adenosine kinase inhibitors.

Abbott Laboratories

Discovery of 4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido[2,3-d]pyrimidine, an orally active, non-nucleoside adenosine kinase inhibitor..

Abbott Laboratories

Design of adenosine kinase inhibitors from the NMR-based screening of fragments.

Abbott Laboratories

Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues.

Metabasis Therapeutics

Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues.

Metabasis Therapeutics