The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.8M data for 1.2M Compounds and 9.2K Targets. Of those, 1,346K data for 622K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

Advanced Search

16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of novel indole derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.EBI
Chinese Academy Of Medical Sciences & Peking Union Medical College
Design, synthesis and biological evaluation of 7-nitro-1H-indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase.EBI
Chinese Academy Of Medical Sciences & Peking Union Medical College
Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.EBI
Metabasis Therapeutics
Discovery of potent and orally active tricyclic-based FBPase inhibitors.EBI
Daiichi Sankyo
Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines.EBI
Pfizer
Orally active aminopyridines as inhibitors of tetrameric fructose-1,6-bisphosphatase.EBI
F. Hoffmann-La Roche
Designing inhibitors against fructose 1,6-bisphosphatase: exploring natural products for novel inhibitor scaffolds.EBI
Boston College
Structure-based drug design of tricyclic 8H-indeno[1,2-d][1,3]thiazoles as potent FBPase inhibitors.EBI
Daiichi Sankyo
Sulfonylureido thiazoles as fructose-1,6-bisphosphatase inhibitors for the treatment of type-2 diabetes.EBI
F. Hoffmann-La Roche
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.EBI
Metabasis Therapeutics
Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors.EBI
Daiichi Sankyo
A library of novel allosteric inhibitors against fructose 1,6-bisphosphatase.EBI
Boston College
Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics.EBI
Metabasis Therapeutics
Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites.EBI
F. Hoffmann-La Roche
Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.EBI
Abbott Laboratories