37 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28146629	65	Identification of High-Potency Human TLR8 and Dual TLR7/TLR8 Agonists in Pyrimidine-2,4-diamines.	University of Minnesota
27270029	39	Incorporation of Phosphonate into Benzonaphthyridine Toll-like Receptor 7 Agonists for Adsorption to Aluminum Hydroxide.	Genomics Institute of Novartis Research Foundation
26351878	24	Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.	University of Kansas
25698055	12	Structural requirements for TLR7-selective signaling by 9-(4-piperidinylalkyl)-8-oxoadenine derivatives.	GlaxoSmithKline
25102141	25	Human Toll-like receptor 8-selective agonistic activities in 1-alkyl-1H-benzimidazol-2-amines.	University of Kansas
25408837	24	Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts.	Sumitomo Dainippon Pharma Co., Ltd
23961878	1	Identification and optimization of pteridinone Toll-like receptor 7 (TLR7) agonists for the oral treatment of viral hepatitis.	Gilead Sciences Inc
23899291	3	Exquisite selectivity for human toll-like receptor 8 in substituted furo[2,3-c]quinolines.	University of Kansas
22837811	12	Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction.	TBA
22924757	16	Structure-activity relationships in human Toll-like receptor 8-active 2,3-diamino-furo[2,3-c]pyridines.	University of Kansas
22239408	31	Toll-like receptor (TLR)-7 and -8 modulatory activities of dimeric imidazoquinolines.	University of Kansas
20232824	17	Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept.	Dainippon Sumitomo Pharma Co., Ltd
32001135	24	Optimization of 8-oxoadenines with toll-like-receptor 7 and 8 activity.	University of Montana
32944143	89	Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9).	Princ
32786235	87	Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists Using a Biochemical TLR8 Antagonist Competition Assay.	Genomics Institute of the Novartis Research Foundation
31784317	25	Further exploration of the structure-activity relationship of imidazoquinolines; identification of potent C7-substituted imidazoquinolines.	University of Kansas
27513008	16	Human Toll-like Receptor (TLR) 8-Specific Agonistic Activity in Substituted Pyrimidine-2,4-diamines.	University of Minnesota
32233366	32	Rationally Designed Small-Molecule Inhibitors Targeting an Unconventional Pocket on the TLR8 Protein-Protein Interface.	The University of Tokyo
31687820	45	Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors	University of Colorado Boulder
31284084	3	Identification and characterization of a novel chemotype for human TLR8 inhibitors.	Freie Universit£t Berlin
24383475	22	Structure-activity relationship analysis of imidazoquinolines with Toll-like receptors 7 and 8 selectivity and enhanced cytokine induction.	University of Minnesota
30344900	36	NLRP3 Modulators for the Treatment of Autoinflammatory Disorders.	Usona Institute
29152046	28	Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8.	University of Minnesota
28537730	9	Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities.	University of Colorado Boulder
17827	156	Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors.	TBA
18173230	5	Inhibition of adenosine deaminase by analogues of adenosine and inosine, incorporating a common heterocyclic base, 4(7)-amino-6(5)H-imidazo[4,5-d]pyridazin-7(4)one.	University of Maryland Baltimore County
17485205	18	Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold.	Eli Lilly and Company
16183021	19	Methylxanthine drugs are chitinase inhibitors: investigation of inhibition and binding modes.	University of Dundee