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65 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
12482437 42 Discovery of a series of (4,5-dihydroimidazol-2-yl)-biphenylamine 5-HT7 agonists.EBI Pfizer Inc
26390077 42 Tactical Approaches to Interconverting GPCR Agonists and Antagonists.EBI University of Minnesota
26483200 100 Synthesis and pharmacological evaluation of piperidine (piperazine)-substituted benzoxazole derivatives as multi-target antipsychotics.EBI Huazhong University of Science and Technology
25936259 55 Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.EBI Jagiellonian University Medical College
24900826 22 Selective 5-HT Receptor Modulators May Deliver Focused Targeting with Fewer Adverse Effects.EBI Therachem Research Medilab (India) Pvt. Ltd.
11454468 35 Discovery and SAR of org 24598-a selective glycine uptake inhibitor.EBI Organon Research and Development Group
10843226 45 First pharmacophoric hypothesis for 5-HT7 antagonism.EBI Universidad Complutense
22738316 35 Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo.EBI Universit£ degli Studi di Bari A. Moro
17517514 63 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.EBI Jagiellonian University Medical College
12825922 207 Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).EBI Virginia Commonwealth University
9599242 23 (R)-(+)-2-[[[3-(Morpholinomethyl)-2H-chromen-8-yl]oxy]methyl] morpholine methanesulfonate: a new selective rat 5-hydroxytryptamine1B receptor antagonist.EBI Astra Arcus AB
2874226 27 Buspirone analogues. 2. Structure-activity relationships of aromatic imide derivatives.EBI TBA
22029386 156 New serotonin 5-HT(1A) receptor agonists with neuroprotective effect against ischemic cell damage.EBI Universidad Complutense de Madrid
21159507 23 Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists.EBI Johnson & Johnson Pharmaceutical Research and Development LLC
15801844 54 Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.EBI TBA
18800769 80 Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III.EBI Università degli Studi di Bari
17517509 21 Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: synthesis and binding affinities for 5-HT(7) and 5-HT(1A) receptors.EBI Università degli Studi di Bari
16002287 9 Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands.EBI Université de Caen
15664850 7 Novel 3-aminochromans as potential pharmacological tools for the serotonin 5-HT(7) receptor.EBI Uppsala University
15588097 95 Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.EBI Università degli Studi di Bari
15501057 20 The impact of spacer structure on 5-HT7 and 5-HT1A receptor affinity in the group of long-chain arylpiperazine ligands.EBI Polish Academy of Sciences
15481983 20 Novel 5-HT7 receptor inverse agonists. Synthesis and molecular modeling of arylpiperazine- and 1,2,3,4-tetrahydroisoquinoline-based arylsulfonamides.EBI State University of Groningen
15341484 159 Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.EBI Merck KGaA
15267230 50 Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists.EBI Uppsala University
12668005 21 Design and synthesis of S-(-)-2-[[4-(napht-1-yl)piperazin-1-yl]methyl]-1,4-dioxoperhydropyrrolo[1,2-a]pyrazine (CSP-2503) using computational simulation. A 5-HT1A receptor agonist.EBI Universidad Complutense
12570387 60 Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.EBI Università degli Studi di Bari
11311055 42 Atropisomeric derivatives of 2',6'-disubstituted (R)-11-phenylaporphine: selective serotonin 5-HT(7) receptor antagonists.EBI Uppsala University
11212112 24 Serotonergic and dopaminergic activities of rigidified (R)-aporphine derivatives.EBI Uppsala University
10753471 64 Derivatives of (R)-1,11-methyleneaporphine: synthesis, structure, and interactions with G-protein coupled receptors.EBI Uppsala University
10585208 212 3-[3-(Piperidin-1-yl)propyl]indoles as highly selective h5-HT(1D) receptor agonists.EBI Merck Sharp & Dohme Research Laboratories
10464021 59 N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents.EBI Knoll Pharmaceuticals
31581003 57 Structure-activity relationships of serotonin 5-HTEBI Normandie Univ
24508140 59 Design, synthesis, radiolabeling and in vivo evaluation of potential positron emission tomography (PET) radioligands for brain imaging of the 5-HT? receptor.EBI Universit£ degli Studi di Bari A. Moro
8246239 84 Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.EBI Solvay Duphar B.V.
23830697 2 Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.EBI National Institute of Radiological Sciences
6581313 2 Synthesis and evaluation of a novel series of N,N-dimethylisotryptamines.EBI TBA
14667218 75 Optimization of the pharmacophore model for 5-HT7R antagonism. Design and synthesis of new naphtholactam and naphthosultam derivatives.EBI Universidad Complutense
14640545 20 Characterization of the 5-HT(7) receptor. Determination of the pharmacophore for 5-HT(7) receptor agonism and CoMFA-based modeling of the agonist binding site.EBI State University of Groningen
30383372 190 Synthesis and Biological Evaluation of Fused Tricyclic Heterocycle Piperazine (Piperidine) Derivatives As Potential Multireceptor Atypical Antipsychotics.EBI Huazhong University of Science and Technology
29767995 34 Structure-Activity Relationships and Therapeutic Potentials of 5-HTEBI Universit£ di Catania
28195704 47 Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors.BDB Promega Biosciences LLC
26637946 27 Benzimidazole derivatives as new a-glucosidase inhibitors and in silico studies.BDB Universiti Teknologi MARA (UiTM)
26218629 26 Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1).BDB Oregon Health & Science University
25746232 16 Inhibitor recognition specificity of MERS-CoV papain-like protease may differ from that of SARS-CoV.BDB University of Illinois at Chicago
9536007 23 Characterization of I2 imidazoline and sigma binding sites in the rat and human stomach.BDB University of Bonn