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Compounds Sorted by Binding Targets per Compound

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Compounds Sorted Alphabetically

Compound Name (alphabetical)	Binding Targets	Enz. Inhib. Data							ITC Data	Alternate Compound Names
		Ki	IC50	Kd	EC50	Koff	Kon	Other
BDBM103467	1,3-beta-glucan synthase component GLS2 Cytochrome P450 1A Cytochrome P450 2C19 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 3A DNA-dependent protein kinase Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Serine-protein kinase ATM Serine/threonine-protein kinase ATR mTOR/FKBP12A/FKBP12B	0	16	0	0	0	0	0	0	US8552004, 2.03
BDBM104102	HIV WT-A pol protein (wild-type clade A) HIV WT-B pol protein (wild-type clade B) HIV WT-C pol protein (wild-type clade C) HIV-1 isolate WT-control pol protein (CNDO control strain) HIV-1 protease HIV-1 protease M1 HIV-1 protease M2 HIV-1 protease M3 HIV-1 protease M4 MDR1 MDRC4	5	0	0	6	0	0	0	0	(2S,3S)-2-(Acetylamino)-N-[(1S,2R)-3-[(6-benzothiazolylsulfonyl)[(2S)-2- methylbutyl]amino]-2-hydroxy-1-(phenylmethyl)propyl]-3-methyl-pentanamide (AG-23)
BDBM104103	HIV WT-A pol protein (wild-type clade A) HIV WT-B pol protein (wild-type clade B) HIV WT-C pol protein (wild-type clade C) HIV-1 isolate WT-control pol protein (CNDO control strain) HIV-1 protease HIV-1 protease M1 HIV-1 protease M2 HIV-1 protease M3 HIV-1 protease M4 MDR1 MDRC4	5	0	0	6	0	0	0	0	N-[(1S,2R)-3-[(6-Benzothiazolylsulfonyl)(cyclohexylmethyl)amino]-2-hydroxy-1- (phenylmethyl)propyl]-3-hydroxy-benzamide (AF-72)
BDBM104107	HIV WT-A pol protein (wild-type clade A) HIV WT-B pol protein (wild-type clade B) HIV WT-C pol protein (wild-type clade C) HIV-1 isolate WT-control pol protein (CNDO control strain) HIV-1 protease HIV-1 protease M1 HIV-1 protease M2 HIV-1 protease M3 HIV-1 protease M4 MDR1 MDRC4	5	0	0	6	0	0	0	0	(2S,3S)-2-(Acetylamino)-N-[(1S,2R)-2-hydroxy-3-[[(4-methoxyphenyl)sulfonyl](2- methylpropyl)amino]-1-(phenylmethyl)propyl]-3-methyl-pentanamide (AF-68)
BDBM104108	HIV WT-A pol protein (wild-type clade A) HIV WT-B pol protein (wild-type clade B) HIV WT-C pol protein (wild-type clade C) HIV-1 isolate WT-control pol protein (CNDO control strain) HIV-1 protease HIV-1 protease M1 HIV-1 protease M2 HIV-1 protease M3 HIV-1 protease M4 MDR1 MDRC4	5	0	0	6	0	0	0	0	N-[(1S,2R)-3-[(Cyclohexylmethyl)[(4-methoxyphenyl)sulfonyl]amino]-2-hydroxy-1- (phenylmethyl)propyl]-3-hydroxy-benzamide (AF-77)
BDBM10458	Acetylcholinesterase Carboxylic ester hydrolase Choline transporter Plasminogen Potassium voltage-gated channel subfamily H member 2 Prothrombin Pteridine reductase 1 Trypsin Twik-RElated Potassium (K+) channel 1 (TREK1) Voltage-gated potassium channel Voltage-gated potassium channel subfamily A member 1/beta-1	4	6	1	1	0	0	0	0	4-AP 4-Aminopyridine 10 CHEMBL284348 DALFAMPRIDINE pyridin-4-amine
BDBM10758	5-hydroxytryptamine receptor 2A Alpha-1A adrenergic receptor Cytochrome P450 2A5 Cytochrome P450 2A6 Lysyl oxidase homolog 2 Phenylethanolamine N-methyltransferase Thrombin & trypsin Trace amine-associated receptor 1 Trace amine-associated receptor 1 (TAAR1) Trypsin-1 trace amine-associated receptor 1	11	3	1	13	0	0	0	0	14C-phenylethylamine 2-phenylethan-1-amine CHEMBL610 phenylethylamine
BDBM107664	11-beta-hydroxysteroid dehydrogenase 11-beta-hydroxysteroid dehydrogenase 1 11-beta-hydroxysteroid dehydrogenase 2 3-beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase type II Cytochrome P450 2C19 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 3A Estradiol 17-beta-dehydrogenase 1 Melanin-concentrating hormone receptor 2/HERG Nuclear receptor subfamily 1 group I member 2	0	15	0	1	0	0	0	0	US8575157, 48
BDBM10840	3-phosphoinositide dependent protein kinase-1 Axin-1/Glycogen synthase kinase-3 beta Casein Kinase I Cyclin-Dependent Kinase 1 (CDK1) Cyclin-Dependent Kinase 5 (CDK5) Dual specificty protein kinase CLK1 Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A Glycogen Synthase Kinase-3, beta Serine/threonine-protein kinase pim-1 cAMP-Dependent Protein Kinase (PKA) cGMP-Dependent Protein Kinase	0	13	0	0	0	0	0	0	4-(5-bromo-1H-indol-3-yl)pyrimidin-2-amine Meridianin C
BDBM10989	Acetylcholinesterase Amine oxidase (flavin-containing) A Amine oxidase [flavin-containing] B Bile salt export pump Canalicular multispecific organic anion transporter 1 Canalicular multispecific organic anion transporter 2 Cholinesterases Monoamine Oxidase Type B (MAO-B) Monoamine oxidase Monoamine oxidase type B (MAO-B) Mutant (I199F) Multidrug resistance-associated protein 4	8	95	0	0	0	0	0	0	(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine CHEMBL887 Rasagiline US9034303, Rasagiline
BDBM11331	72 kDa type IV collagenase Bone morphogenetic protein 1 Carbonic Anhydrase IV Carbonic anhydrase 1 Carbonic anhydrase 2 Collagenase (ChC) Interstitial collagenase Matrix metalloproteinase-9 Meprin A subunit beta Neutrophil collagenase Stromelysin-1	11	3	0	0	0	0	0	0	2-[benzyl(4-methoxybenzene)sulfonamido]-N-hydroxyacetamide CGS 27023A Analog 22 Hydroxamate 12
BDBM119695	Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 10 Histone deacetylase 11 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	0	11	0	0	0	0	0	0	US8685992, 14
BDBM119703	Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 10 Histone deacetylase 11 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	0	22	0	0	0	0	0	0	US8685992, 27
BDBM119704	Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 10 Histone deacetylase 11 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	0	11	0	0	0	0	0	0	US8685992, 28
BDBM119709	Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 10 Histone deacetylase 11 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	0	11	0	0	0	0	0	0	US8685992, 37
BDBM123687	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Homo sapiens phosphodiesterase 2A (PDE2A) Phosphodiesterase 11A (PDE11A) Phosphodiesterase 7B (PDE7B) Phosphodiesterase 8 Phosphodiesterase 9A cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cAMP-specific 3',5'-cyclic phosphodiesterase 4B cAMP-specific 3',5'-cyclic phosphodiesterase 7B cGMP-inhibited 3',5'-cyclic phosphodiesterase B cGMP-specific 3',5'-cyclic phosphodiesterase	0	20	0	0	0	0	0	0	US8741907, 3 US9067945, 2
BDBM124200	Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 10 Histone deacetylase 11 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	0	11	0	0	0	0	0	0	US8748458, 4
BDBM13054	Carbonic Anhydrase VA Carbonic Anhydrase VB Carbonic Anhydrase XIII Carbonic Anhydrase XIV Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 2 Carbonic anhydrase 4 Carbonic anhydrase 6 (CA-VI) Carbonic anhydrase 7 Carbonic anhydrase 9	13	0	0	0	0	0	0	0	(2R,4R)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1,7-thieno[2,3-b]thiopyran-6-sulfonamide Dorzolamide, DZA sulfonamide 5
BDBM13055	Carbonic Anhydrase III Carbonic Anhydrase VA Carbonic Anhydrase VB Carbonic Anhydrase XIII Carbonic Anhydrase XIV Carbonic anhydrase 1 Carbonic anhydrase 12 Carbonic anhydrase 2 Carbonic anhydrase 4 Carbonic anhydrase 7 Carbonic anhydrase 9	38	0	2	0	0	0	0	0	CHEMBL283695 Compound 8 Topiramate Sulfamide Analogue 8 amino-N-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}sulfonamide
BDBM13080	72 kDa type IV collagenase Collagenase 3 Disintegrin and metalloproteinase domain-containing protein 17 Interstitial collagenase Matrix metalloproteinase-12 (MMP12) Matrix metalloproteinase-14 (MMP14) Matrix metalloproteinase-7 (MMP7) Matrix metalloproteinase-9 Meprin A subunit beta Neutrophil collagenase Stromelysin-1	9	16	0	0	0	0	0	0	CGS 27023A Analog 3 N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]acetamide
BDBM14030	Rho-kinase (ROCK II) cAMP-Dependent Protein Kinase (PKA) cAMP-Dependent Protein Kinase (PKA) Mutant (E127D) cAMP-Dependent Protein Kinase (PKA) Mutant (L49I) cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/Q181K/T183A) cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/V123M/E127D/Q181K/T183A) cAMP-Dependent Protein Kinase (PKA) Mutant (L49I/V123M/Q181K/T183A) cAMP-Dependent Protein Kinase (PKA) Mutant (Q181K/T183A) cAMP-Dependent Protein Kinase (PKA) Mutant (T183A) cAMP-Dependent Protein Kinase (PKA) Mutant (V123M) cAMP-Dependent Protein Kinase (PKA) Mutant (V123M/Q181K/T183A)	0	11	0	0	0	0	0	0	KT5720 hexyl (15R,16S,18S)-16-hydroxy-15-methyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaene-16-carboxylate
BDBM14772	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Phosphodiesterase 8 Phosphodiesterase Type 10 (PDE10A) Phosphodiesterase Type 11 (PDE11A) Phosphodiesterase Type 2 (PDE2A) Phosphodiesterase Type 3 (PDE3B) Phosphodiesterase Type 4 (PDE4B) Phosphodiesterase Type 4 (PDE4D) Phosphodiesterase Type 5 (PDE5A) Phosphodiesterase Type 7 (PDE7B) Phosphodiesterase Type 9 (PDE9A)	0	11	0	0	0	0	0	0	(R,S)-Mesopram 5-(4-methoxy-3-propoxy-phenyl)-5-methyl-1,3-oxazolidin-2-one 5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one Daxalipram
BDBM154245	1,3-beta-glucan synthase component GLS2 Cytochrome P450 3A Sodium channel alpha subunit Sodium channel protein type 10 subunit alpha Sodium channel protein type 2 alpha subunit Sodium channel protein type 5 subunit alpha Sodium channel protein type 8 subunit alpha Sodium channel protein type 9 subunit alpha Sodium channel protein type IX alpha subunit Voltage-gated sodium channel subunit alpha Nav1.3 (Nav1.3) Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4)	0	22	0	0	0	0	0	0	US9012443, 261
BDBM154563	Chromobox protein homolog 7 (CBX7) E3 ubiquitin-protein ligase (UHRF1) Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) Lysine-specific demethylase 5A MBT domain-containing protein 1 (MBTD1) Methyl-lysine binding protein (53BP1) PHD finger protein 1 (PHF1) PHD finger protein 19 (PHF19) PHD finger protein 23 (PHF23) Tumor suppressor p53-binding protein 1	0	11	0	0	0	0	0	0	N-(3-(Tert-butylamino)propyl)-3-iodobenzamide (19)
BDBM154564	Chromobox protein homolog 7 (CBX7) E3 ubiquitin-protein ligase (UHRF1) Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) Lysine-specific demethylase 5A MBT domain-containing protein 1 (MBTD1) Methyl-lysine binding protein (53BP1) PHD finger protein 1 (PHF1) PHD finger protein 19 (PHF19) PHD finger protein 23 (PHF23) Tumor suppressor p53-binding protein 1	0	11	0	0	0	0	0	0	N-(3-(Tert-butylamino)propyl)-3-isopropylbenzamide (20)
BDBM154565	Chromobox protein homolog 7 (CBX7) E3 ubiquitin-protein ligase (UHRF1) Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3) Lysine-specific demethylase 5A MBT domain-containing protein 1 (MBTD1) Methyl-lysine binding protein (53BP1) PHD finger protein 1 (PHF1) PHD finger protein 19 (PHF19) PHD finger protein 23 (PHF23) Tumor suppressor p53-binding protein 1	0	11	0	0	0	0	0	0	N-(3-(Tert-butylamino)propyl)-3-(trifluoromethyl)benzamide (21)
BDBM15458	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 2 Epidermal growth factor receptor Heat shock protein beta-1 Mitogen-activated protein kinase 14 Mitogen-activated protein kinase 8 Mitogen-activated protein kinase 9 PKC alpha and beta-2 Protein kinase C alpha type RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase Lck	1	13	0	0	0	0	0	0	4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidazol-5-yl]-2-methoxypyrimidine 4-[4-(4-fluorophenyl)-1-piperidin-4-yl-1H-imidazol-5-yl]-2-methoxypyrimidine CHEMBL95692 SB-242235 SB242235
BDBM155921	1,3-beta-glucan synthase component GLS2 ATP-sensitive inward rectifier potassium channel 1 Acetylcholinesterase Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 3A L-type calcium channel alpha-1c/beta-2/alpha2delta-1 Renal Outer Medullary Potassium (ROMK) Sodium channel protein type 5 subunit alpha Sodium-dependent serotonin transporter Somatostatin receptor type 1	0	29	0	0	0	0	0	0	US9018211, 2A
BDBM159748	Amine oxidase (flavin-containing) A JAK1/JAK2/TYK2 JAK1/TYK2 JAK2/JAK1 JAK2/TYK2 JAK3/JAK1 Non-receptor tyrosine-protein kinase TYK2 Tyrosine-protein kinase JAK1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase JAK3 Vascular endothelial growth factor receptor 2	0	27	0	0	0	0	0	0	US9035074, 2
BDBM164638	1,3-beta-glucan synthase component GLS2 Cytoplasmic tyrosine-protein kinase BMX Epidermal growth factor receptor Receptor protein-tyrosine kinase erbB-4 Receptor tyrosine-protein kinase erbB-2 TEC family kinase Tyrosine-protein kinase BTK Tyrosine-protein kinase ITK/TSK Tyrosine-protein kinase JAK3 Tyrosine-protein kinase TEC Tyrosine-protein kinase TXK	1	23	8	0	0	0	0	0	BDBM166759 US10604504, Example 223 US9688629, 123 US9802915, Example 123 US9920031, Example 223
BDBM16590	3-phosphoinositide dependent protein kinase-1 Axin-1/Glycogen synthase kinase-3 beta Cyclin-Dependent Kinase 1 (CDK1) Cyclin-Dependent Kinase 2 (CDK2) Fibroblast growth factor receptor 1 Platelet-derived growth factor receptor beta RAC-alpha serine/threonine-protein kinase Serine/threonine-protein kinase Chk1/2 Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 2 cAMP-dependent protein kinase (PKA)	1	11	0	0	0	0	0	0	2-(1H-indazol-3-yl)-1H-1,3-benzodiazole 3-(1H-benzimidazol-2-yl)-1H-indazole CHEMBL383990 Indazole Compound 2
BDBM17289	ATP-binding cassette sub-family G member 2 Bile salt export pump Corticosteroid-binding globulin Cytochrome P450 1B1 Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) Estradiol receptor beta (ERβ) Estrogen receptor Ghrelin O-acyltransferase Solute carrier organic anion transporter family member 1A1 Steryl-sulfatase Testis-specific androgen-binding protein	4	18	1	8	0	0	0	0	(1S,10R,11S,15S)-5-hydroxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-trien-14-one CHEMBL1405 Estrone Estrone (E1) Estrone, 15 Estrovarin Kestrone Theelin Unigen [2,4,6,7-3H]-E1 [2,4,6,7-3H]-Estrone folliculin
BDBM178100	Cereblon/Histone deacetylase 1 Cereblon/Histone deacetylase 2 Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	3	13	0	0	0	0	0	0	BRD3308
BDBM180052	Anandamide amidohydrolase Cytochrome P450 1A Cytochrome P450 2C19 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 3A Cytochrome P450 3A5 (CYP3A5) LDL-associated phospholipase A2 Monoacylglycerol lipase ABHD6 Monoglyceride Lipase (MGL) Monoglyceride lipase	0	14	0	0	0	0	0	0	US9133148, 9aq
BDBM18125	Excitatory amino acid transporter 1 Excitatory amino acid transporter 2 Excitatory amino acid transporter 3 Excitatory amino acid transporter 4 GRIA3 Glutamate receptor ionotropic, NMDA 1 Glutamate transporter homolog Glycosylasparaginase (GA) Metabotropic glutamate receptor 1 Metabotropic glutamate receptor 2 Metabotropic glutamate receptor 6	5	8	1	3	0	0	0	0	(2S)-2-aminobutanedioic acid Aspartate CHEMBL274323 L-Aspartate L-Aspartic acid, 2 L-[14C]aspartate
BDBM18353	Alpha-mannosidase 2C1 Lactase-glycosylceramidase Lysosomal acid glucosylceramidase Lysosomal alpha-glucosidase Maltase-glucoamylase Mannosidase 2 alpha 1 Mannosidase 2, alpha B1 Trehalase alpha-Glucosidase (α-Glucosidase) alpha-Glucosidase (alpha-Glu) alpha-glucosidase (Gaa)	3	10	0	1	0	0	0	0	(2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine-3,4,5-triol CHEMBL75971 N-Methyl-DNJ US9181184, 2
BDBM18358	α-galactosidase α-glucosidase β-galactosidase Beta-galactosidase Beta-glucosidase Ceramide glucosyltransferase Lysosomal acid glucosylceramidase Probable alpha-glucosidase Os06g0675700 Sucrase-isomaltase alpha-Glucosidase (alpha-Glu) alpha-glucosidase (Gaa)	7	23	0	0	0	0	0	0	(2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol N-Nonyl-DNJ
BDBM18525	Androgen Receptor Androgen receptor Bile salt export pump Canalicular multispecific organic anion transporter 1 Canalicular multispecific organic anion transporter 2 Estrogen receptor Glucocorticoid Multidrug resistance-associated protein 4 Progesterone Receptor (PR) Progesterone receptor mineralocorticoid	21	64	0	7	0	0	0	0	Bicalutamide CHEMBL409 N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorobenzene)sulfonyl]-2-hydroxy-2-methylpropanamide US9126941, Bicalutamide US9682960, CAS
BDBM191597	Lysine-specific demethylase 4C Lysine-specific demethylase 5A Lysine-specific demethylase 5A (KDM5A(aa 1-1090)-Flag) Lysine-specific demethylase 5A (KDM5A(aa 1-588)ΔAP) Lysine-specific demethylase 5A (KDM5A(aa 1-739)ΔAP(2C-2S)) Lysine-specific demethylase 5B Lysine-specific demethylase 5B (KDM5B(aa 1-604)ΔAP) Lysine-specific demethylase 5B (KDM5B(aa 1-755)ΔAP) Lysine-specific demethylase 5C Lysine-specific demethylase 5C (KDM5C(aa 1-789)ΔAP) Lysine-specific demethylase 5D (KDM5D(aa 1-760)ΔAP)	0	18	2	0	0	0	0	0	3-((1-(2-(4,4-difluoropiperidin-1-yl)ethyl)-5-fluoro-1H-indazol-3-yl)amino)-isonicotinic acid (N11) US10040779, Example 73 US10336727, Example 73 US9617242, Example 73
BDBM191602	Lysine-specific demethylase 4C Lysine-specific demethylase 5A Lysine-specific demethylase 5A (KDM5A(aa 1-1090)-Flag) Lysine-specific demethylase 5A (KDM5A(aa 1-588)ΔAP) Lysine-specific demethylase 5A (KDM5A(aa 1-739)ΔAP(2C-2S)) Lysine-specific demethylase 5B Lysine-specific demethylase 5B (KDM5B(aa 1-604)ΔAP) Lysine-specific demethylase 5B (KDM5B(aa 1-755)ΔAP) Lysine-specific demethylase 5C Lysine-specific demethylase 5C (KDM5C(aa 1-789)ΔAP) Lysine-specific demethylase 5D (KDM5D(aa 1-760)ΔAP)	0	16	2	0	0	0	0	0	3-((1-methyl-1Hpyrrolo[2,3-b]pyridin-3-yl)amino)isonicotinic acid (N12) US10040779, Example 52 US10336727, Example 52 US9617242, Example 52
BDBM191641	Cereblon/Histone deacetylase 6 Histone deacetylase 1 Histone deacetylase 10 Histone deacetylase 11 Histone deacetylase 2 Histone deacetylase 3 Histone deacetylase 4 Histone deacetylase 5 Histone deacetylase 7 Histone deacetylase 8 Histone deacetylase 9	0	11	0	0	0	0	0	0	US9186318, 13
BDBM193124	3',5'-cyclic phosphodiesterase Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Cytochrome P450 1A Cytochrome P450 2C19 Cytochrome P450 2C9 Cytochrome P450 2D6 Cytochrome P450 3A Homo sapiens phosphodiesterase 2A (PDE2A) Phosphodiesterase 10A (PDE10A2) Phosphodiesterase 3 and 5 (PDE3 and PDE5) Phosphodiesterase Type 10 (PDE10A)	0	17	0	0	0

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