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Compounds Sorted by Binding Targets per Compound

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30   31   32   33   34   35   36   37   38   39   40   41   42   43   44   45   46   47   48   49   50   51   52   53   54   55   
56   57   58   59   60   61   62   63   64   65   66   67   68   69   70   73   74   75   76   77   79   81   84   86   89   95   
96   100   108   109   120   124   130   137   143   154   156   168   186   224   240   259   276   278   284   303   
304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
385   386   388   389   390   391   392   393   394   395   397   398   401   403   404   406   408   418   427   
429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • β-Carbonic anhydrase 2 (CA 2)
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 3 (CA III)
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • Carbonic anhydrases; II & IX
  • Delta carbonic anhydrase
  • Gamma-carbonic anhydrase
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
379 Ki 6 IC50 16 Kd
  • 6-ethoxy-1,3-benzothiazole-2-sulfonamide
  • CHEMBL18
  • Ethamide
  • Ethoxazolamide
  • Ethoxzolamide
  • Ethoxzolamide (EZA)
  • Ethoxzolamide, EZM
  • Sulfonamide, 3
  • US10172837, Ethoxyzolamide
  • sulfonamide 3
  • β-Carbonic anhydrase 2 (CA 2)
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase (mtCA 3)
  • Carbonic Anhydrase 2 (Can2)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • Carbonic anhydrases; II & IX
  • Delta carbonic anhydrase
  • Multidrug resistance-associated protein 4
  • PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE)
  • beta-Carbonic Anhydrase
191 Ki 9 IC50 3 Kd
  • (4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide
  • (R)-4-(ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno(3,2-E)-1,2-thiazine-6-sulfonamide 1,1-dioxide
  • AL-4862
  • Azopt
  • Brinzolamide (BRZ)
  • brinzolamide
  • Aurora kinase A/Targeting protein for Xklp2
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Epithelial discoidin domain-containing receptor 1
  • Fibroblast growth factor receptor 2
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • Leukocyte tyrosine kinase receptor
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase 7
  • PKC alpha and beta-2
  • Protein kinase C iota type/zeta type
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • RAF proto-oncogene serine/threonine-protein kinase
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
34 IC50 2 Kd
  • US9255110, 17
  • κ opioid receptor (KOR D138A)
  • κ opioid receptor (KOR D138N)
  • κ opioid receptor (KOR E297A)
  • κ opioid receptor (KOR H291A)
  • κ opioid receptor (KOR H291F)
  • κ opioid receptor (KOR I135A)
  • κ opioid receptor (KOR I294A)
  • κ opioid receptor (KOR I316A)
  • κ opioid receptor (KOR K200A)
  • κ opioid receptor (KOR K227A)
  • κ opioid receptor (KOR L212A)
  • κ opioid receptor (KOR M142A)
  • κ opioid receptor (KOR M226A)
  • κ opioid receptor (KOR Q115A)
  • κ opioid receptor (KOR Y119A)
  • κ opioid receptor (KOR Y119F)
  • κ opioid receptor (KOR Y139A)
  • κ opioid receptor (KOR Y139F)
  • κ opioid receptor (KOR Y312A)
  • κ opioid receptor (KOR Y312F)
  • κ opioid receptor (KOR Y313A)
  • κ opioid receptor (KOR Y313F)
  • κ opioid receptor (KOR Y320A)
  • κ opioid receptor (KOR Y320F)
  • κ opioid receptor (KOR Y66A)
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Norepinephrine transporter
  • OPRD1
  • Opioid receptors; mu & delta
  • Sodium-dependent serotonin transporter
  • mu/kappa opioid receptor
63 Ki 7 IC50 10 Kd 35 EC50
  • N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]decan-8-yl]acetamide
  • N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspiro(4,5)dec-8-yl)benzeneacetamide
  • U-69593
  • U69,593
  • [3H]U69593
  • 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial
  • Alpha-chymotrypsin
  • Arachidonate 5-lipoxygenase
  • Beta-lactamase AmpC
  • Bile acid transporter
  • Cyclooxygenase
  • Cytochrome P450 11A1
  • Cytochrome P450 11B1
  • Cytochrome P450 11B1, mitochondrial
  • Cytochrome P450 11B2 (CYP11B2)
  • Cytochrome P450 17A1
  • Cytochrome P450 19A1
  • Cytochrome P450 21
  • Cytochrome P450 24A1
  • Cytochrome P450 2A2
  • Cytochrome P450 2C11
  • Cytochrome P450 3A
  • Cytochrome P450 51
  • Cytochrome P450 7A1
  • Gonadotropin-releasing hormone receptor
  • Heme Oxygenase 1 (HO-1)
  • Heme Oxygenase 2 (HO-2)
  • Indoleamine 2,3-dioxygenase
  • Malate dehydrogenase cytoplasmic
  • P-glycoprotein 1
  • Phospholipase A2, major isoenzyme
  • Potassium voltage-gated channel subfamily H member 2
  • Sterol 14α-demethylase (CYP51)
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A4
  • Uridine-5'-diphosphoglucuronosyltransferase 1A6
  • Uridine-5'-diphosphoglucuronosyltransferase 2B10
  • Uridine-5'-diphosphoglucuronosyltransferase 2B7
15 Ki 132 IC50 6 Kd
  • CHEMBL295698
  • Ketoconazole
  • Nizoral
  • Panfungol
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • Adrenergic receptor alpha-2
  • Adrenergic receptor beta
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Histone H1
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2 and M4
  • Norepinephrine Monoamine transporters
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin 2 (5-HT2) receptor
  • Sodium-dependent serotonin transporter
  • Transporter
171 Ki 19 IC50 1 Kd
  • 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
  • CHEMBL715
  • OLANZAPINE
  • Olansek
  • US8802672, Olanzapine
  • Zyprexa
  • olanzapine
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • 5-hydroxytryptamine receptor 7 (5HT7)
  • ADRA2C
  • Adrenergic receptor alpha-2
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • DRD1
  • HTR1D
  • HTR1F
  • HTR2C
  • HTR6
  • HTR7
  • Histamine H1 receptor
  • Histamine H4 receptor
  • Muscarinic acetylcholine receptor M2
  • Norepinephrine transporter
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • adrenergic Alpha2
123 Ki
  • (S)-mianserin
  • Lerivon
  • MIANSERIN
  • MIANSERIN (+)
  • MIANSERIN (-)
  • Tolvon
  • 5-hydroxytryptamine receptor 2A
  • ANF
  • Adenosine Kinase (AK)
  • Adenylate cyclase Forskolin
  • Alpha-1A adrenergic receptor
  • Angiotensin
  • Arg-vasopressin V1
  • Beta-2 adrenergic receptor
  • Bombesin
  • Calcium channel
  • Chloride channel, TBOB
  • Cholecystokinin receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • DRD1
  • EGF
  • Ecto-5'-nucleotidase (e5'NT)
  • GRIA3
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid type B receptor subunit 1
  • Glutamate receptor ionotropic, NMDA 1
  • Glutamate receptor ionotropic, kainate 1
  • Glycine
  • Inositol Triphosphate
  • Interleukin
  • NGF
  • Norepinephrine transporter
  • Potassium Channel
  • SOMATOSTATIN
  • Sigma non-opioid intracellular receptor 1
  • Substance K
  • VIP
  • adrenergic Alpha2
42 Ki 3 IC50 1 EC50
  • (+/-)-trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine
  • (6aR,12bR)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol
  • 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol
  • CHEMBL43345
  • Dihydrexidine, DHX
  • ADC-11
  • ADC-14 protein
  • ADC-16 protein
  • ADC-18 protein
  • Bacterial beta-lactamase TEM
  • Beta-lactamase
  • Beta-lactamase (SHV-1)
  • Beta-lactamase (TEM-1)
  • Beta-lactamase ACC-4
  • Beta-lactamase ADC-33
  • Beta-lactamase AmpC
  • Beta-lactamase BRO-1
  • Beta-lactamase GES-13
  • Beta-lactamase OXA-1
  • Beta-lactamase SCO-1
  • Beta-lactamase SHV-5
  • Beta-lactamase SHV-55
  • Beta-lactamase TEM-125
  • Beta-lactamase class C
  • Beta-lactamase pse-1
  • Beta-lactamase type II
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Carbapenem-hydrolizing beta-lactamase SFC-1
  • Carbepenem-hydrolyzing beta-lactamase KPC
  • Class A beta-lactamase BlaC (BlaC)
  • Class A carbapenemase KPC-2
  • Class D β-lactamase (OXA-1)
  • Class D beta-lactamase
  • Extended-spectrum beta-lactamase CTX-M-53
  • Gil1
  • Leukocyte elastase
  • SHV-1 beta-lactamase
8 Ki 73 IC50
  • CHEMBL777
  • MM 14151
  • US9120808, Clavulanic acid potassium salt
  • antibiotic MM 14151
  • clavulanic acid
  • 1,3-beta-glucan synthase component GLS2
  • Adrenergic Alpha
  • Bile salt export pump
  • Butyrylcholinesterase (BuChE)
  • Calcium channel
  • Calcium channel (Type L)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450
  • Cytochrome P450 2D1
  • Cytochrome P450 2D18
  • Cytochrome P450 2D2
  • Cytochrome P450 2D3
  • Cytochrome P450 2D6
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Histidine-rich protein
  • Multidrug and toxin extrusion protein 1
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 4
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily D member 2
  • Potassium voltage-gated channel subfamily H member 2
  • Reverse transcriptase
  • Sodium channel protein type I I alpha subunit
  • Solute carrier family 22 member 1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
  • Uridine-5'-diphosphoglucuronosyltransferase 1A4
  • Uridine-5'-diphosphoglucuronosyltransferase 1A6
  • Uridine-5'-diphosphoglucuronosyltransferase 2B10
  • Uridine-5'-diphosphoglucuronosyltransferase 2B7
  • Voltage-dependent L-type calcium channel subunit alpha-1C
  • Voltage-gated L-type calcium channel
7 Ki 76 IC50
  • (6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol
  • CARDIOQUIN
  • CHEMBL1294
  • CIN-QUIN
  • DURAQUIN
  • QUINACT
  • QUINAGLUTE
  • QUINALAN
  • QUINATIME
  • QUINIDEX
  • QUINIDINE
  • QUINORA
  • US9402878, Quinidine
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDC2-like kinase 3 (CLK3)
  • Cyclin-dependent kinase 19
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 3 (CDK3)
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 8
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • Dual specificity protein kinase CLK2
  • Dual specificity protein kinase CLK4
  • Dual specificity protein kinase TTK
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-regulated kinases 1B
  • Extracellular signal-regulated kinase 5 (ERK5)
  • Glycogen synthase kinase-3
  • Interferon-induced, double-stranded RNA-activated protein kinase
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 15
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 4
  • Mitogen-activated protein kinase 6
  • Protein kinase C alpha type
  • Serine/threonine-protein kinase Aurora-C
  • Serine/threonine-protein kinase PCTAIRE-1
  • Serine/threonine-protein kinase PCTAIRE-2
  • Serine/threonine-protein kinase PCTAIRE-3
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK3
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase STK16 (STK16)
1 IC50 33 Kd
  • (R,S)-3-(3-(2,3-dihydroxypropylamino)phenyl)-4-(5-fluoro-1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
  • CHEMBL1082152
  • 1,3-beta-glucan synthase component GLS2
  • ABL Mutant (T315I)
  • Axin-1/Glycogen synthase kinase-3 beta
  • Bcr-Abl
  • Cereblon/BCR/ABL
  • Coiled-coil domain-containing protein 6/Tyrosine-protein kinase receptor RET
  • Cytochrome P450
  • Ephrin type-A receptor 2 (EPHA2)
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 2
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Glycogen Synthase Kinase 3 (GSK3)
  • Leucine-rich repeat kinase 2 (LRRK2 t-WT)
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Protein cereblon/Tyrosine-protein kinase SRC
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase Src (c-Src)
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor-interacting serine/threonine-protein kinase 3
  • SRC
  • Serine/threonine-protein kinase RIPK2
  • TEL/KDR
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase ABL1 (c-Abl)
  • Tyrosine-protein kinase Lyn
  • VHL/BCR-ABL1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
1 Ki 60 IC50 3 Kd 2 EC50
  • 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
  • 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide
  • CHEMBL1171837
  • PONATINIB
  • US10464902, Ponatinib
  • US9255107, AP24534
  • Acetyl-CoA acetyltransferase, mitochondrial
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldose reductase (AR)
  • Coagulation factor VII/tissue factor
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • DNA Ligase I
  • DNA polymerase beta
  • Dual specificity protein phosphatase 3
  • Epidermal growth factor receptor
  • G-protein coupled bile acid receptor 1
  • GP41
  • Glycogen phosphorylase, muscle form
  • Hypoxia-inducible factor prolyl hydroxylase
  • Leukocyte common antigen
  • Low molecular weight phosphotyrosine protein phosphatase
  • Nitric oxide synthase, inducible
  • Nuclear factor NF-kappa-B
  • Pancreatic alpha-amylase
  • Pancreatic triacylglycerol lipase
  • Phospholipase A2
  • Phosphotyrosine protein phosphatase
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Protease
  • Protein Tyrosine Phosphatase PTPB
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Signal transducer and activator of transcription 3
  • T-cell protein-tyrosine phosphatase
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
3 Ki 113 IC50 4 EC50
  • NSC-114945
  • OLEANOLIC_ACID
  • Oleanolic acid
  • Oleanolic acid (OA)(Compound 1)
  • Angiopoietin-1 receptor
  • Apoptosis Signal-regulating Kinase 1 (ASK1)
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity mitogen-activated protein kinase kinase 5
  • Dual specificity protein kinase TTK
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 3
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin-like growth factor I receptor
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase kinase kinase 1
  • Nuclear receptor subfamily 2 group C member 2
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Protein kinase C theta type
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase B-raf
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
38 IC50
  • CHEMBL1614725
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • CDK3/Cyclin E
  • CDK4/Cyclin D3
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 10
  • Cyclin-dependent kinase 12
  • Cyclin-dependent kinase 19
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 20
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 6
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 8
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase
  • Extracellular signal-regulated kinase 5 (ERK5)
  • MAP kinase ERK1
  • Mitogen-activated protein kinase 15
  • Mitogen-activated protein kinase 4
  • Mitogen-activated protein kinase 6
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
  • Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma
  • Serine/threonine-protein kinase Aurora-C
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK2
  • Serine/threonine-protein kinase PLK3
44 Kd
  • CHEMBL4445812
  • ALK tyrosine kinase receptor/Nucleophosmin
  • Bcr-Abl
  • Centrosomal protein 43/RET
  • Coiled-coil domain-containing protein 6
  • E3 ubiquitin-protein ligase XIAP/JAK2
  • Fibroblast growth factor receptor
  • Hepatocyte growth factor receptor
  • High affinity nerve growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET
  • MER intracellular domain/EGFR extracellular domain chimera
  • Macrophage colony stimulating factor receptor
  • Macrophage-stimulating protein receptor
  • NTRK1/NTRK2
  • Neurotrophic tyrosine kinase receptor
  • Protein cereblon/Platelet-derived growth factor receptor alpha
  • Protein cereblon/Stem cell growth factor receptor
  • Protein cereblon/Tyrosine-protein kinase SRC
  • Protein cereblon/Tyrosine-protein kinase receptor FLT3
  • Proto-oncogene tyrosine-protein kinase ROS
  • SRC
  • TEC family kinase
  • TEL/KDR
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor Tie-1
  • VEGF-receptor 2 and Fibroblast growth factor receptor 1
  • VEGF-receptor 2 and Fibroblast growth factor receptor 2
  • VHL/PDGFRB
  • Vascular endothelial growth factor receptor 1 and 2 (Flt-1 and KDR)
38 IC50
  • CHEMBL4640601
  • 26S Proteasome regulatory subunit Rpn11 (Rpn11)
  • Acetylcholinesterase
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 6
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • Death-associated protein kinase 1
  • Death-associated protein kinase 2
  • Death-associated protein kinase 3
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Intestinal alkaline phosphatase
  • Neuraminidase
  • Serine/threonine-protein kinase 17A
  • Serine/threonine-protein kinase 17B (STK17B)
  • Serine/threonine-protein kinase 33
  • Thrombin
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase SYK
  • Xanthine dehydrogenase
  • drug resistance protein 2
35 IC50 2 EC50
  • (2Z)-2-(3,4-dihydroxybenzylidene)-6-hydroxy-coumaran-3-one
  • (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-6-hydroxy-1-benzofuran-3-one
  • (2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-6-hydroxy-3-benzofuranone
  • (2Z)-2-[[3,4-bis(oxidanyl)phenyl]methylidene]-6-oxidanyl-1-benzofuran-3-one
  • MLS000863576
  • SMR000440743
  • SULFURETIN
  • cid_5281295
  • ATP-binding cassette sub-family G member 2
  • Chloroquine resistance transporter
  • Cytochrome P450 3A
  • Gag polyprotein
  • HIV-1 Protease
  • HIV-1 Protease A Subtype
  • HIV-1 Protease A Subtype Mutant (V82F/I84V)
  • HIV-1 Protease AE
  • HIV-1 Protease AE Mutant (V82F)
  • HIV-1 Protease AE-P
  • HIV-1 Protease AE-P Mutant (F82V)
  • HIV-1 Protease B Subtype
  • HIV-1 Protease B Subtype Mutant (V82F)
  • HIV-1 Protease B Subtype Mutant (V82F/I84V)
  • HIV-1 Protease C Subtype
  • HIV-1 Protease C Subtype Mutant (V82F/I84V)
  • HIV-1 Protease Mutant (L10I/L90M)
  • HIV-1 Protease Mutant (M46I/I54V)
  • HIV-1 Protease Mutant (V82A/I84V)
  • HIV-1 Protease Mutant (V82F/I84V)
  • HIV-1 Protease Mutant M1 (L10I, G48V, I54V, L63P, V82A)
  • HIV-1 Protease Mutant M2 (D30N, L63P, N88D)
  • HIV-1 Protease Mutant M3 (L10I, L63P, A71V, G73S, I84V, L90M)
  • HIV-1 Protease Mutant, A-1
  • HIV-1 Protease Mutant, ANAM-11
  • HIV-1 Protease Mutant, MDR-HM
  • HIV-1 Protease Mutant, MDR-QM
  • HIV-1 Protease Mutant, NAM-10
  • HIV-1 protease
  • Human immunodeficiency virus type 1 protease
  • P-glycoprotein (P-gp)
  • P-glycoprotein 1
  • P-glycoprotein 1 and 3 (MDR1a/MDR1b)
35 Ki 32 IC50 2 Kd 1 Koff 1 Kon
18 ΔG°
  • (2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-decahydroisoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinolin-2-ylformamido)butanediamide
  • CHEMBL114
  • Fortovase
  • Invirase
  • Ro 31-8959
  • SQV
  • Saquinavir
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7 (5HT7)
  • Adrenergic alpha1B
  • Adrenergic receptor alpha-2
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Cerebral cortex alpha adrenergic receptor
  • Cytochrome P450 3A
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine receptor
  • Genome polyprotein
  • HTR6
  • Histamine H1 receptor
  • P-glycoprotein 1
  • P-glycoprotein 1 and 3 (MDR1a/MDR1b)
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
67 Ki 7 IC50 4 Kd 2 EC50
  • BROMOCRIPTINE
  • Bromocriptine+ (GTP+)
  • Bromocriptine+ (GTP-)