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Compounds Sorted by Binding Targets per Compound

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429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1)
  • Estradiol 17-beta-dehydrogenase 2
8 IC50
  • US8546392, 19
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1)
  • Estradiol 17-beta-dehydrogenase 2
8 IC50
  • US8546392, 59
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1)
  • Estradiol 17-beta-dehydrogenase 2
8 IC50
  • US8546392, 70
  • JAK1 (aa 850-1154)
  • JAK2 (aa 808-1132)
  • JAK3 (aa 781-1124)
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
10 IC50
  • US10206907, Compound 234
  • US8563545, 11
  • D(2) dopamine receptor
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Jumonji domain-containing protein 2A (JMJD2A)
  • Jumonji domain-containing protein 2C (JMJD2C)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 5C
7 IC50
  • 4HQ derivative 4
  • D(2) dopamine receptor
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Jumonji domain-containing protein 2A (JMJD2A)
  • Jumonji domain-containing protein 2C (JMJD2C)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 5C
7 IC50
  • 4HQ derivative 6
  • D(2) dopamine receptor
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Jumonji domain-containing protein 2A (JMJD2A)
  • Jumonji domain-containing protein 2C (JMJD2C)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 5C
7 IC50
  • 4HQ derivative 7
  • D(2) dopamine receptor
  • Histone Lysine Demethylase
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Jumonji domain-containing protein 2A (JMJD2A)
  • Jumonji domain-containing protein 2C (JMJD2C)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 5C
7 IC50
  • 4HQ derivative 8
  • Acetylcholinesterase
  • Butyrylcholinesterase
  • Butyrylcholinesterase (BChE)
  • Butyrylcholinesterase (BuChE)
  • Carboxylic ester hydrolase
  • Cholinesterases
  • Sodium-dependent serotonin transporter
4 Ki 88 IC50
  • (S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate
  • 3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl N-methyl carbamate
  • 3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate
  • 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate
  • CHEMBL636
  • ENA-713
  • Ethyl-methyl-carbamic acid 3-((R)-1-dimethylamino-ethyl)-phenyl ester
  • Ethyl-methyl-carbamic acid 3-((S)-1-dimethylamino-ethyl)-phenyl ester
  • Ethyl-methyl-carbamic acid 3-(1-dimethylamino-ethyl)-phenyl ester
  • Exelon
  • RIVASTIGMINE
  • Rivastigmine
  • Rivastigmine (1)
  • SDZ-212-713
  • SDZ-ENA-713
  • Acetylcholinesterase
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Butyrylcholinesterase (BChE)
  • Cholinesterase
  • Monoamine Oxidase Type B (MAO-B)
  • Monoamine oxidase
2 Ki 19 IC50
  • (3R)-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl N-ethyl-N-methylcarbamate hydrochloride
  • Aminoindan deriv. (R)18b
  • Aminoindan deriv. (R)18b.HCl
  • N-propargylaminoindan (R)18b.HCl
  • R-CPAI
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1s
  • Plasma kallikrein
  • Plasminogen
  • Transcription initiation factor IIA
  • Vitamin K-dependent protein C
8 Ki
  • US8598206, Table 6, 1
  • Acetylcholinesterase
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Butyrylcholinesterase (BChE)
  • Cholinesterase
  • Monoamine Oxidase Type B (MAO-B)
  • Monoamine oxidase
13 IC50
  • 3-{2-[methyl(prop-2-yn-1-yl)amino]propyl}phenyl N-hexyl-N-methylcarbamate
  • CHEMBL356385
  • Phenethylamine deriv. 53d
  • CDK2/CycE
  • Casein Kinase I
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Mitogen-activated protein kinase 1
  • Voltage-gated calcium channel subunit alpha Cav2.2
6 IC50 1 EC50
  • (2R)-2-({6-[benzyl(methyl)amino]-9-(propan-2-yl)-9H-purin-2-yl}amino)butan-1-ol
  • N6-methyl-(R)-roscovitine
  • R-2-[6-(Benzyl-methyl-amino)-9-isopropyl-9H-purin-2-ylamino]-butan-1-ol
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrases; II & IX
7 Ki
  • 1-pentafluorophenylamido-5-sulfonamidoindane
  • 2,3,4,5,6-pentafluoro-N-(5-sulfamoyl-2,3-dihydro-1H-inden-1-yl)benzamide
  • CHEMBL205867
  • Indanesulfonamide Derivative 11c
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Epidermal growth factor receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
27 IC50
  • DACOMITINIB
  • US8623883, No. 2
  • 5-hydroxytryptamine receptor 2B
  • Adrenergic Alpha
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Proto-oncogene tyrosine-protein kinase receptor Ret
1 Ki 7 IC50
  • US8629135, SW-07
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 1
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 2
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 3
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 4
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki 3 IC50
  • US9695194, 5
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 6
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 7
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 8
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 9
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 10
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 11
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 12
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 13
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 14
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 15
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 16
  • Cathepsin G
  • Chymotrypsin
  • Kallikrein 14
  • Kallikrein 5
  • Kallikrein 7
  • Prothrombin
  • Trypsin-1
7 Ki
  • US9695194, 17
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 4
  • 4-Amino-5-chloro-3-fluorobenzenesulfonamide
  • 4-amino-3-chloro-5-fluorobenzene-1-sulfonamide
  • halogenosulfanilamide deriv. 6
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 5
  • 4-Amino-5-bromo-3-fluorobenzenesulfonamide
  • 4-amino-3-bromo-5-fluorobenzene-1-sulfonamide
  • halogenosulfanilamide deriv. 7
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 7
  • 4-Amino-3,5-dichlorobenzenesulfonamide
  • 4-amino-3,5-dichlorobenzene-1-sulfonamide
  • halogenosulfanilamide deriv. 9
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 8
  • 4-Amino-5-bromo-3-chlorobenzenesulfonamide
  • 4-amino-3-bromo-5-chlorobenzene-1-sulfonamide
  • halogenosulfanilamide deriv. 10
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 9
  • 4-Amino-3-chloro-5-iodobenzenesulfonamide
  • 4-amino-3-chloro-5-iodobenzene-1-sulfonamide
  • halogenosulfanilamide deriv. 11
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 1
  • 2-N-(4-amino-3-chlorobenzene)-1,3,4-thiadiazole-2,5-disulfonamide
  • 5-(4-Amino-3-chlorobenzenesulfonamido)-1,3,4-thiadiazole-2-sulfonamide
  • aminobenzolamide 17c
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 2
  • 2-N-(4-amino-3-bromo-5-fluorobenzene)-1,3,4-thiadiazole-2,5-disulfonamide
  • 5-{[(4-amino-3-bromo-5-fluorophenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
  • aminobenzolamide 19
  • β-Carbonic anhydrase 2 (CA 2)
  • β-Carbonic anhydrase 3 (CA 3)
  • Carbonic Anhydrase (mtCA 1)
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
7 Ki
  • β-CA inhibitor, 3
  • 2-N-(4-amino-3-fluoro-5-iodobenzene)-1,3,4-thiadiazole-2,5-disulfonamide
  • 5-{[(4-amino-3-fluoro-5-iodophenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
  • aminobenzolamide 20
  • Astrosclerin-3
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
32 Ki
  • 4-sulfamoyl-N-[2-(4-sulfamoylphenyl)ethyl]benzamide
  • CHEMBL51668
  • Sulfonamide 2
  • 72 kDa type IV collagenase
  • Collagenase 3
  • Interstitial collagenase
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
5 Ki 7 IC50
  • 4-{[4-(4-Chlorophenoxy)phenyl]sulfonyl}-N-hydroxy tetrahydro-2H-pyran-4-carboxamide
  • 4-{[4-(4-chlorophenoxy)benzene]sulfonyl}-N-hydroxyoxane-4-carboxamide
  • alpha-sulfone 21
  • PI3-kinase class I
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 3-kinase regulatory subunit beta
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
14 IC50
  • US9682141, 529
  • US9682141, 54
  • 72 kDa type IV collagenase
  • Collagenase 3
  • Interstitial collagenase
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Stromelysin-1
1 Ki 12 IC50
  • (2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-methylbutanoic acid
  • CHEMBL43152
  • alpha-arylsulfonylamino carboxylate 2S
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
3 Ki 21 IC50
  • CHEMBL178681
  • CHEMBL359657
  • US8609708, 1
  • US8609708, 31
  • [5-(pyridin-3-yl)thiophen-2-yl]methanamine
  • nicotine 3-heteroaromatic analogue 1a
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
3 Ki 12 IC50
  • CHEMBL178090
  • US8609708, 2
  • US8609708, 47
  • [5-(pyridin-3-yl)furan-2-yl]methanamine
  • nicotine 3-heteroaromatic analogue 2a
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
3 Ki 11 IC50
  • 3-(3-methylthiophen-2-yl)pyridine
  • CHEMBL179669
  • US8609708, 4
  • nicotine 3-heteroaromatic analogue 4
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
3 Ki 9 IC50
  • 3-(thiophen-3-yl)pyridine
  • CHEMBL361153
  • US8609708,11
  • nicotine 3-heteroaromatic analogue 8
  • Cytochrome P450 2A6
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2E1
  • Cytochrome P450 3A
3 Ki 10 IC50
  • 3-(4-methylthiophen-3-yl)pyridine
  • CHEMBL179704
  • US8609708, 17
  • US8609708,17
  • nicotine 3-heteroaromatic analogue 11
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 33
  • Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
  • Interstitial collagenase
  • Matrix metalloproteinase-9
  • Stromelysin-1
9 IC50
  • US8772478, 15
  • US8772478, 8
  • JAK1 (aa 850-1154)
  • JAK1 (aa 866-1154)
  • JAK2 (aa 808-1132)
  • JAK3 (aa 781-1124)
  • TYK2 (aa 871-1187)
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
8 IC50
  • US10206907, Compound 330
  • US8796457, 1
  • US9505754, 1
  • 5-hydroxytryptamine receptor 1A
  • Adrenergic receptor alpha-2
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • CD44 antigen
  • Nicotinamide N-methyltransferase (NNMT)
  • Phenylethanolamine N-methyltransferase
20 Ki 1 IC50 2 Kd
  • 1,2,3,4-tetrahydroisoquinoline
  • CHEMBL14346
  • THIQ 6
  • tetrahydroisoquinoline
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
7 Ki
  • (4S)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-2H,3H,4H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide
  • CHEMBL51533
  • sulfonamide 6
  • 1,3-beta-glucan synthase component GLS2
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 2
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Proto-oncogene tyrosine-protein kinase Src
  • Vascular endothelial growth factor receptor 2
13 IC50
  • US10689705, Compound 7
  • US8829199, 196
  • 1,3-beta-glucan synthase component GLS2
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 2
  • Fibroblast growth factor receptor 3
  • Fibroblast growth factor receptor 4
  • Proto-oncogene tyrosine-protein kinase Src
  • Vascular endothelial growth factor receptor 2
13 IC50
  • US10689705, Compound 46
  • US8829199, 200
  • Coagulation factor X
  • Kallikrein 6
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin II
  • Vitamin K-dependent protein C
9 Ki 1 IC50
  • 4-{[(3S)-3-[(7-methoxynaphthalene-2-)(methyl)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}thiophene-2-carboximidamide
  • 4-{[(3S)-3-{[(7-methoxynaphthalen-2-yl)sulfonyl](methyl)amino}-2-oxopyrrolidin-1-yl]methyl}thiophene-2-carboximidamide
  • CHEMBL84638
  • RPR120844
  • Sulfonamidopyrrolidinone
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Vitamin K-dependent protein C
9 Ki
  • 4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfonylamino)-2-oxopyrrolidin-1-ylmethyl]benzamidine
  • 4-hydroxy-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide
  • CHEMBL93854
  • Sulfonamidopyrrolidinone 20a
  • 3',5'-cyclic phosphodiesterase
  • Lipopolysaccharide-induced tumor necrosis factor-alpha factor
  • Tumor necrosis factor
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • phosphodiesterase 4B2
  • phosphodiesterase 4D
10 IC50
  • US10085990, Example 103
  • US10568888, Example 103
  • US8853226, 103
  • US9393245, 103
  • Epidermal growth factor receptor
  • Focal adhesion kinase 1
  • Hepatocyte growth factor receptor
  • Insulin-like growth factor I receptor
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 14
  • Receptor tyrosine-protein kinase erbB-2
10 IC50
  • 2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}carbamate
  • CHEMBL412367
  • pyrrolo[2,1-f][1,2,4]triazine analog 9b
  • JAK1/TYK2
  • JAK2/JAK1
  • JAK3/JAK1
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
11 IC50
  • US8895544, 4
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Vitamin K-dependent protein C
9 Ki
  • 4-hydroxy-3-[[(3S)-2-oxo-3-(9-thia-5-azabicyclo[4.3.0]nona-2,4,7,10-tetraen-8-ylsulfonylamino)pyrrolidin-1-yl]methyl]benzenecarboximidamide
  • 4-hydroxy-3-{[(3S)-2-oxo-3-{thieno[3,2-b]pyridine-2-sulfonamido}pyrrolidin-1-yl]methyl}benzene-1-carboximidamide
  • CHEMBL330572
  • RPR131247
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Urokinase (uPA) Mutant (S190A)
  • Urokinase-type plasminogen activator
12 Ki
  • 2-{5-[amino(iminiumyl)methyl]-1H-1,3-benzodiazol-2-yl}-6-(cyclopentyloxy)benzen-1-olate
  • APC-10655
  • CA-06
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Urokinase-type plasminogen activator
10 Ki
  • APC-9850
  • {amino[6-chloro-2-(3,5-dichloro-2-hydroxyphenyl)-1H-indol-5-yl]methylidene}azanium
  • Coagulation factor X
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin-1
  • Urokinase-type plasminogen activator
23 Ki
  • 2-{5-[amino(iminiumyl)methyl]-6-chloro-1H-1,3-benzodiazol-2-yl}-6-phenylbenzen-1-olate
  • APC-10762
  • Coagulation factor X
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Tryptase
  • Urokinase (uPA) Mutant (S190A)
  • Urokinase-type plasminogen activator
8 Ki
  • 4-Iodobenzo[b]thiophene-2-carboxamidine
  • APC-6860
  • CA-01
  • CRA-6860
  • [amino(4-iodo-1-benzothiophen-2-yl)methylidene]azanium
  • Anandamide amidohydrolase
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Fatty-acid amide hydrolase 1
12 IC50
  • US9682953, 20.A-1
  • Anandamide amidohydrolase
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Fatty-acid amide hydrolase 1
12 IC50
  • US9682953, 20.A-3
  • Anandamide amidohydrolase
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Fatty-acid amide hydrolase 1
13 IC50
  • US9682953, 20.A-5
  • Anandamide amidohydrolase
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Fatty-acid amide hydrolase 1
15 IC50
  • US9682953, 20.A-10
  • US9682953, 20.A-9
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 1
  • Phosphodiesterase 3
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cGMP-specific 3',5'-cyclic phosphodiesterase
5 Ki 19 IC50
  • 6-(4-imidazol-1-ylphenyl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one
  • 6-[4-(1H-imidazol-1-yl)phenyl]-5-methyl-2,3,4,5-tetrahydropyridazin-3-one
  • CI 930
  • CI-930
  • EML4 ALK Fusion Protein
  • Proto-oncogene tyrosine-protein kinase ROS
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Replicase polyprotein 1ab
  • TEL/AXL
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor UFO
10 IC50
  • Gilteritinib
  • US8969336, 547
  • US8969336, 577
  • 3',5'-cyclic phosphodiesterase
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 10A (PDE10A)
  • Phosphodiesterase 11A
  • Phosphodiesterase 4
  • Phosphodiesterase 6
  • Phosphodiesterase 8
11 IC50
  • US8969376, 1.006
  • Coagulation factor X
  • Hepsin
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin-1
  • Urokinase-type plasminogen activator
7 Ki
  • 2-amino-5-[(2-hydroxy-3-phenylbenzene)amido]-1H-1,3-benzodiazol-3-ium
  • CA-25
  • Sodium channel alpha subunit
  • Sodium channel protein type 2 alpha subunit
  • Sodium channel protein type 5 subunit alpha
  • Sodium channel protein type 7 subunit alpha
  • Sodium channel protein type 8 subunit alpha
  • Sodium channel protein type 9 subunit alpha
  • Voltage-gated sodium channel
9 IC50
  • US8952169, 389
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 23
  • US9682983, 23
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 26
  • US9682983, 26
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 32
  • US9682983, 32
  • Protein kinase B (Akt 1)
  • Protein kinase C (PKC)
  • Protein kinase C, gamma
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase AKT
  • Serine/threonine-protein kinase AKT2
  • cAMP-Dependent Protein Kinase (PKA)
12 IC50
  • 3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl]pyridin-3-yl}oxy)propyl]-1H-indole
  • bispyridinylethylene, 2
  • pyridine-base inhibitor 1b
  • trans-bispyridinylethylene analog 2q
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Leukocyte common antigen
  • Protein-tyrosine phosphatase
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Tyrosine-protein phosphatase non-receptor type 11
9 IC50
  • US8987474, NSC-87877
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase (bsNOS)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
8 Ki 1 Kd
  • 4-methyl-6-[2-(3-{methyl[2-(methylamino)ethyl]amino}phenyl)ethyl]pyridin-2-amine (13)
  • US9951014, Name 10a
  • Nitric Oxide Synthase, endothelial
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase (bsNOS)
  • Nitric oxide synthase, brain
  • Nitric oxide synthase, endothelial
  • Nitric oxide synthase, inducible
  • Nitric-oxide synthase, brain
8 Ki 1 Kd
  • 4-methyl-6-[2-(6-{methyl[2-(methylamino)ethyl]amino}pyridin-2-yl)ethyl]pyridin-2-amine (15)
  • US9951014, Name 14a
  • DNA-dependent protein kinase
  • Heat Shock Protein 90 (Hsp90)
  • Heat shock protein 75 kDa, mitochondrial
  • Heat shock protein 90 beta
  • Heat shock protein HSP 90-alpha
  • Heat shock protein HSP 90-beta
  • Receptor tyrosine-protein kinase erbB-2
3 Ki 19 IC50 7 Kd 13 EC50
4 ΔG°
  • (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-en-1-ylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
  • 17-(Allylamino)geldanamycin
  • 17-AAG
  • 17AAG
  • CHEMBL109480
  • GLD-36
  • Tanespimycin
  • AMP deaminase 1 (hAMPD1)
  • AMP deaminase 1 (mAMPD1)
  • AMP deaminase 1 (rAMPD1)
  • AMP deaminase 2
  • AMP deaminase 2 (rAMPD2)
  • AMP deaminase 3 (hAMPD3)
  • AMP deaminase 3 (rAMPD3)
7 IC50
  • 6-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methyl)phenyl]pyridine-3-carboxylic acid (Compound 2)
  • AMP deaminase 1 (hAMPD1)
  • AMP deaminase 1 (mAMPD1)
  • AMP deaminase 1 (rAMPD1)
  • AMP deaminase 2
  • AMP deaminase 2 (rAMPD2)
  • AMP deaminase 3 (hAMPD3)
  • AMP deaminase 3 (rAMPD3)
7 IC50
  • 6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methyl)phenyl]pyridine-3-carboxylic acid (Compound 3)
  • HIV-1 Reverse Transcriptase
  • HIV-1 Reverse Transcriptase Mutant (G190A)
  • HIV-1 Reverse Transcriptase Mutant (K103N)
  • HIV-1 Reverse Transcriptase Mutant (P236L)
  • HIV-1 Reverse Transcriptase Mutant (V106A)
  • HIV-1 Reverse Transcriptase Mutant (Y181C)
  • HIV-1 Reverse Transcriptase Mutant (Y188L)
9 IC50
  • 2-ethyl-9-methyl-5-(1H-pyrrol-3-yl)-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one
  • Dipyridodiazepinone deriv. 42
  • dipyridodiazepinone 2
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 38
  • US9682983, 38
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
10 IC50
  • US10017516, Compound 39
  • US9682983, 39
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 40
  • US9682983, 40
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
10 IC50
  • US10017516, Compound 41
  • US9682983, 41
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
  • TGF-beta receptor type-1
10 IC50
  • US10017516, Compound 43
  • US9682983, 43
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 48'
  • US9682983, 48
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor type-1B/Activin receptor-like kinase 4 (ALK-4)
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Serine/threonine-protein kinase receptor R3
  • Serine/threonine-protein kinase receptor R3 (ALK1)
10 IC50
  • US10017516, Compound 60
  • US9682983, 60
  • Enoyl-ACP Reductase (FabI)
  • Enoyl-ACP Reductase (InhA)
  • Enoyl-ACP reductase (FabI1)
  • Enoyl-ACP reductase (Wt ypFabV)
  • Enoyl-ACP reductase T276S (T276S ypFabV)
  • Enoyl-[acyl-carrier-protein] reductase [NADH]
  • Enoyl-[acyl-carrier-protein] reductase [NADH] (ftuFabl)
5 Ki 5 IC50
  • 5-Hexyl-2-phenoxy-phenol
  • 5-hexyl-2-phenoxylphenol
  • 5-hexyl-2-phenoxyphenol
  • 6PP
  • AIDS227446
  • PT04
  • Aldehyde reductase
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldose Reductase (ALR2) Mutant (L300P)
  • Aldose reductase
  • Aldose reductase (ALR2)
  • Aldose reductase (AR)
  • Aldose reductase L301M (AR)
81 IC50
3 ΔG°
  • (4S)-6-fluoro-2,3-dihydrospiro[1-benzopyran-4,4'-imidazolidine]-2',5'-dione
  • CHEMBL266497
  • Sorbinil
  • Aldehyde reductase
  • Aldo-keto reductase family 1 member C21
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldose reductase
  • Aldose reductase (ALR2)
  • Aldose reductase (AR)
  • Bile salt export pump
2 Ki 42 IC50
1 ΔG°
  • 2-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-N-methylmethanethioamido}acetic acid
  • Alredase
  • CHEMBL436
  • N-{[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]carbonothioyl}-N-methylglycine
  • Tolrestat
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 2
  • Cereblon/Histone deacetylase 6
  • HDAC1/NCOR2
  • HDAC2/NCOR2
  • HDAC3/NCOR2
  • Histone deacetylase 3
7 IC50
  • SR-3212
  • US10807944, Compound RLS2-137
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 2
  • Cereblon/Histone deacetylase 6
  • HDAC1/NCOR2
  • HDAC2/NCOR2
  • HDAC3/NCOR2
  • Histone deacetylase 3
7 IC50
  • SR-3367
  • US10807944, Compound RLS2-284
  • Aldehyde reductase
  • Aldo-keto reductase family 1 member C21
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldose reductase
  • Aldose reductase (AR)
  • Aldose reductase-related protein 1
  • Glyoxalase I
2 Ki 30 IC50
  • (4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4-dihydrophthalazin-1-yl)acetic acid
  • 2-(4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl}-3,4-dihydrophthalazin-1-yl)acetic acid
  • Alond
  • CHEMBL10372
  • Xedia
  • Zopolrestat
  • 3-phosphoinositide dependent protein kinase-1
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase Chk1/2
  • cAMP-dependent protein kinase (PKA)
1 Ki 7 IC50
  • 4-[3-(1H-1,3-benzodiazol-2-yl)-1H-indazol-6-yl]-2-methoxyphenol
  • 4-[3-(1H-benzimidazol-2-yl)-1H-indazol-6-yl]-2-methoxyphenol
  • Indazole Compound 1
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Intestinal alkaline phosphatase (IAP)
  • Tissue non-specific alkaline phosphatase (TNAP)
5 Ki 3 IC50
  • 1-N-(4-fluorobenzene)benzene-1,4-disulfonamide
  • aromatic sulfonamide compound 26
  • Protein kinase B (Akt 1)
  • Protein kinase C (PKC)
  • Protein kinase C, gamma
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase AKT
  • Serine/threonine-protein kinase AKT2
  • cAMP-Dependent Protein Kinase (PKA)
7 IC50
  • 6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-chloropyridin-3-yl}isoquinoline
  • Isoquinoline-pyridine, 10a
  • Protein kinase B (Akt 1)
  • Protein kinase C (PKC)
  • Protein kinase C, gamma
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase AKT
  • Serine/threonine-protein kinase AKT2
  • cAMP-Dependent Protein Kinase (PKA)
7 IC50
  • 6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]pyridin-3-yl}isoquinolin-3-amine
  • Isoquinoline-pyridine, 10y
  • 3-phosphoinositide dependent protein kinase-1
  • Epidermal growth factor receptor
  • Insulin-like growth factor I receptor
  • Platelet-derived growth factor receptor beta
  • Receptor tyrosine-protein kinase erbB-2
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
7 IC50
  • (3Z)-4-methyl-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one
  • CHEMBL85403
  • Indolinone based inhibitor, 1a
  • 3-phosphoinositide dependent protein kinase-1
  • Cyclic GMP-AMP synthase
  • Inhibitor of nuclear factor kappa-B kinase subunit epsilon
  • Serine/threonine-protein kinase TBK1
  • Serine/threonine-protein kinase ULK1
  • Serine/threonine-protein kinase ULK2
  • [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
8 IC50 3 Kd 1 EC50
  • BX-795
  • BX-795, 3
  • N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
  • N-{3-[(5-iodo-4-{[3-(thiophen-2-ylformamido)propyl]amino}pyrimidin-2-yl)amino]phenyl}pyrrolidine-1-carboxamide
  • Complement factor D
  • Complement factor D (FD) catalytic domain (Human fD)
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Kalligrein-7 Y180R (KLK7)
  • Potassium voltage-gated channel subfamily H member 2
10 IC50
  • 1-(2-((1R,3S,5R)-3-((6-Bromopyridin-2-yl)carbamoyl)-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)-1H-indazole-3-carboxamide (7)
  • US9085555, 727
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2078
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2079
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2081
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2082
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2139
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2061
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2064
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2088
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2097
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2103
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2118
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2131
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
7 IC50
  • US9096593, P-2198
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2001
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2028
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-1622
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
7 IC50
  • US9096593, P-1679
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-1562
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
8 IC50
  • US9096593, P-2043
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