Compile Data Set for Download or QSAR
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Found 20 of affinity data for UniProtKB/TrEMBL: P43251
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480933(US10906888, Example 147)
Affinity DataIC50:  40nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480971(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrimidin-5-y...)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480917(7-oxa-2-azaspiro[3.5]non-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480919(US10906888, Example 133)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480929(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrimidin-5-y...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480931(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[(1S)-1-(pyrazin-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480965(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[2-(pyrazin-2-yl)...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480921(US10906888, Example 135)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50585537(CHEMBL5084938)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480968(US10906888, Example 185)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480783(US10906888, Example 1)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50585533(CHEMBL5094835)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480981(US10906888, Example 198 | US10906888, Example 199 ...)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480973(US10906888, Example 190)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM394644(3-[(2-{[1-(pyrimidin-5-yl)cyclopropyl]amino}pyrimi...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480990(US10906888, Example 150)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480928(8-oxa-2-azaspiro[4.5]dec l{2-[(pyrazin-2-ylmethyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480932(US10906888, Example 146)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBiotinidase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50585535(CHEMBL5086259)
Affinity DataIC50:  6.20E+4nMAssay Description:Inhibition of N-terminal FLAG/His6-tagged human biotinidase expressed in COS cells using biotinyl-7-amino-4-trifluoromethylcoumarin as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed