BDBM50224109 1-(4-(methylsulfonyl)phenyl)-5-p-tolyl-3-(trifluoromethyl)-1H-pyrazole::4-[5-(4-methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]-1-methylsulfonyl-benzene::CHEMBL241970::Celecoxib

SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=VXPBYVGXCVDFLZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224109   

TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Keio University

Curated by ChEMBL
LigandPNGBDBM50224109(1-(4-(methylsulfonyl)phenyl)-5-p-tolyl-3-(trifluor...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of purified ovine COX-1 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50224109(1-(4-(methylsulfonyl)phenyl)-5-p-tolyl-3-(trifluor...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of recombinant CYP2C9 by fluorescence inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Keio University

Curated by ChEMBL
LigandPNGBDBM50224109(1-(4-(methylsulfonyl)phenyl)-5-p-tolyl-3-(trifluor...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant COX-2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed