BDBM39351 CHLOROTHIAZIDE::MLS000028398::SMR000058429::US10172837, Chlorothiazide::cid_2720

SMILES NS(=O)(=O)c1cc2c(cc1Cl)N=CNS2(=O)=O

InChI Key InChIKey=JBMKAUGHUNFTOL-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 39351   

TargetGenome polyprotein(West Nile virus)
University Of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM39351(CHLOROTHIAZIDE | MLS000028398 | SMR000058429 | US1...)
Affinity DataIC50: >5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Naia Metabolic

US Patent
LigandPNGBDBM39351(CHLOROTHIAZIDE | MLS000028398 | SMR000058429 | US1...)
Affinity DataIC50:  460nMAssay Description:Compounds which are CAIs are well known in the art, see for example, Pastorekova et al, Journal of Enzyme Inhibition and Medicinal Chemistry, 19(3), ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProtein LANA1(Human herpesvirus 8)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM39351(CHLOROTHIAZIDE | MLS000028398 | SMR000058429 | US1...)
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay