BDBM50225220 CHEMBL559::D-thyroxine::O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine::dextrothyroxine
SMILES N[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
InChI Key InChIKey=XUIIKFGFIJCVMT-GFCCVEGCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50225220
TargetSolute carrier organic anion transporter family member 1C1(Mus musculus)
The University Of Tokyo
Curated by ChEMBL
The University Of Tokyo
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:TP_TRANSPORTER: inhibition of L-T4 uptake in Oatp14-expressing HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of bound [125I]L-T3 rat plasma membrane 3,5,3'' L-triiodothyronine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of the bound [125I]L-T3 rat liver nuclear L-triiodothyronine receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 7.17E+3nMpH: 4.4Assay Description:Inhibition of transthyretin fibril formation at pH 4.4More data for this Ligand-Target Pair