BDBM50423778 Leukerin::MERCAPTOPURINE::Mercaleukin::Mercaptopurine anhydrous::Purinethol

SMILES S=c1[nH]cnc2nc[nH]c12

InChI Key InChIKey=GLVAUDGFNGKCSF-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50423778   

TargetBile salt export pump(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50423778(Leukerin | MERCAPTOPURINE | Mercaleukin | Mercapto...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis)
Pontifical Catholic University Of Rio Grande Do Sul

Curated by ChEMBL
LigandPNGBDBM50423778(Leukerin | MERCAPTOPURINE | Mercaleukin | Mercapto...)
Affinity DataKd:  7.94E+4nMAssay Description:Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed