BDBM50012893 2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxy-acetamide::2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-N-hydroxy-acetamide(Indomethacin series)::2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}ethanehydroxamic acid::CHEMBL295829::Oxametacin

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NO)c2c1

InChI Key InChIKey=AJRNYCDWNITGHF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50012893   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of 5-lipoxygenase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  7.50E+3nMAssay Description:Tested for inhibition of 5-Lipoxygenase (ARBL) in calcium-stimulated rat basophillic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Tested for inhibition of cyclooxygenase (ARBC) in calcium-stimulated rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails Article
TargetProstaglandin G/H synthase 1/2(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase in intact RBL-1 cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nitromed

Curated by ChEMBL
LigandPNGBDBM50012893(2-[1-(4-Chloro-benzoyl)-5-methoxy-2-methyl-1H-indo...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as effect on A23187-induced thromboxane B2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed