BDBM1004 N-(3-{1-[4-hydroxy-6,6-bis(2-methylpropyl)-2-oxo-5,6-dihydro-2H-pyran-3-yl]propyl}phenyl)-1-methyl-1H-imidazole-4-sulfonamide::N-[3-[1-(5,6-Dihydro-4-hydroxy-6,6-diisobutyl-2-oxo-2H-pyran-3-yl)propyl]phenyl]-1-methyl-1H-imidazole-4-sulfonamide::Tipranavir deriv. 15
SMILES CCC(C1C(=O)CC(CC(C)C)(CC(C)C)OC1=O)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1
InChI Key InChIKey=HPIWZFKLTDFQSI-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1004
Affinity DataKi: 3nM ΔG°: -11.5kcal/molepH: 5.0 T: 2°CAssay Description:HIV-1 protease was purified and refolded from E. coli inclusion bodies. The substrate used spans the p17-p24 processing site (R-V-S-Q-N-Y-P-I-V-Q-N-K...More data for this Ligand-Target Pair