BDBM100423 US10383835, Compound 1153::US11123311, Compound APAU::US8501783, 1153

SMILES CC(=O)N1CCC(CC1)NC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=HUDQLWBKJOMXSZ-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 100423   

TargetBifunctional epoxide hydrolase 2(Human)
Eicosis

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataKi:  19.5nMAssay Description:FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBifunctional epoxide hydrolase 2(Human)
Eicosis

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataKi:  19.5nMAssay Description:Any of a number of standard assays for determining epoxide hydrolase activity can be used to determine inhibition of sEH. For example, suitable assay...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetBifunctional epoxide hydrolase 2(Pig)
The Regents of The University of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  13nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpoxide hydrolase 1(Cat)
The Regents of The University of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  450nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpoxide hydrolase 1(Dog)
The Regents of The University of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  500nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpoxide hydrolase(Horse)
The Regents of The University of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  121nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpoxide hydrolase 1(Human)
The Regents of The University of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition assay of human soluble epoxide hydrolases.More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetEpoxide hydrolase(Sheep)
The Regents of The University of California

US Patent
LigandPNGBDBM100423(US10383835, Compound 1153 | US11123311, Compound A...)
Affinity DataIC50:  67nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In DepthDetails US Patent