BDBM100740 CHEMBL391608::US8507714, 29

SMILES COc1ccc(Cl)cc1CC1CNC(=O)CN(C1=O)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=SOSJFTNPSZEBHV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 100740   

TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50:  34nMAssay Description:Inhibitory activity of the compounds for recombinant human chymase was measured by method of Pasztor et al. (Pasztor et al., Acta Biol. Hung. 42:285-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin G(Homo sapiens (Human))
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human neutrophil cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Daiichi Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Daiichi Sankyo

US Patent
LigandPNGBDBM100740(CHEMBL391608 | US8507714, 29)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed