BDBM103729 US10206907, Compound 2::US11000528, Cpd # 3::US8563545, 3

SMILES O=C(Nc1nc2cccc(-c3cccc(CN4CCOCC4)c3)n2n1)C1CC1

InChI Key InChIKey=OAAYBVHGHNLLIA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 103729   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103729(US10206907, Compound 2 | US11000528, Cpd # 3 | US8...)
Affinity DataIC50:  291nMAssay Description:In vitro inhibition assay using various enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103729(US10206907, Compound 2 | US11000528, Cpd # 3 | US8...)
Affinity DataIC50:  291nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103729(US10206907, Compound 2 | US11000528, Cpd # 3 | US8...)
Affinity DataIC50:  550nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In DepthDetails US Patent