BDBM103909 JNK3 inhibitor 6::US8562945, 242

SMILES NOOSc1ccc(CC[N@@]23CC(=O)O[Re]2[N]2=C(C3)C=CC=C2)cc1

InChI Key InChIKey=IIDDSQRWDXXIIL-UHFFFAOYSA-M

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 103909   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50:  109nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50:  11.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

US Patent
LigandPNGBDBM103909(JNK3 inhibitor 6 | US8562945, 242)
Affinity DataIC50:  170nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their ability to inhibit carbonic anhydrase isozymes II and IX in vito.More data for this Ligand-Target Pair
In DepthDetails US Patent