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BDBM104211 US8575145, 88

SMILES: FC1CNCCC1Oc1cc(F)cc2ccc(nc12)-c1nnc2ccccn12

InChI Key: InChIKey=KXDUVJWVGXIEPX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 104211   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))
BDBM104211
PNG
(US8575145, 88)
Show SMILES FC1CNCCC1Oc1cc(F)cc2ccc(nc12)-c1nnc2ccccn12
Show InChI InChI=1S/C20H17F2N5O/c21-13-9-12-4-5-15(20-26-25-18-3-1-2-8-27(18)20)24-19(12)17(10-13)28-16-6-7-23-11-14(16)22/h1-5,8-10,14,16,23H,6-7,11H2
PDB
MMDB

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KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 8n/an/an/an/a7.422



Array BioPharma Inc

US Patent


Assay Description
The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...


US Patent US8575145 (2013)


BindingDB Entry DOI: 10.7270/Q2M90797
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase PIM-3


(Rattus norvegicus (Rat))
BDBM104211
PNG
(US8575145, 88)
Show SMILES FC1CNCCC1Oc1cc(F)cc2ccc(nc12)-c1nnc2ccccn12
Show InChI InChI=1S/C20H17F2N5O/c21-13-9-12-4-5-15(20-26-25-18-3-1-2-8-27(18)20)24-19(12)17(10-13)28-16-6-7-23-11-14(16)22/h1-5,8-10,14,16,23H,6-7,11H2
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 24n/an/an/an/a7.422



Array BioPharma Inc

US Patent


Assay Description
The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...


US Patent US8575145 (2013)


BindingDB Entry DOI: 10.7270/Q2M90797
More data for this
Ligand-Target Pair
Serine/threonine-protein kinase pim-2


(Homo sapiens (Human))
BDBM104211
PNG
(US8575145, 88)
Show SMILES FC1CNCCC1Oc1cc(F)cc2ccc(nc12)-c1nnc2ccccn12
Show InChI InChI=1S/C20H17F2N5O/c21-13-9-12-4-5-15(20-26-25-18-3-1-2-8-27(18)20)24-19(12)17(10-13)28-16-6-7-23-11-14(16)22/h1-5,8-10,14,16,23H,6-7,11H2
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 502n/an/an/an/a7.422



Array BioPharma Inc

US Patent


Assay Description
The assay for the determination of PIM activity is based on the incorporation of [33P] ATP into PIM2tide substrate and capture of the radiolabeled pe...


US Patent US8575145 (2013)


BindingDB Entry DOI: 10.7270/Q2M90797
More data for this
Ligand-Target Pair