BDBM104688 US8569311, 2-1

SMILES Cc1ccc(c(c1)C(=O)N1CCCC(COc2ccc(F)nc2)C1)-n1nccn1

InChI Key InChIKey=RBRJTDKOGIFTFG-UHFFFAOYSA-N

Data  2 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104688   

TargetOrexin receptor type 2(Rattus norvegicus (Rat))
Merch Sharp & Dohme Corp.

US Patent
LigandPNGBDBM104688(US8569311, 2-1)
Show SMILES Cc1ccc(c(c1)C(=O)N1CCCC(COc2ccc(F)nc2)C1)-n1nccn1
Show InChI InChI=1S/C21H22FN5O2/c1-15-4-6-19(27-24-8-9-25-27)18(11-15)21(28)26-10-2-3-16(13-26)14-29-17-5-7-20(22)23-12-17/h4-9,11-12,16H,2-3,10,13-14H2,1H3
Affinity DataKi:  29nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Merch Sharp & Dohme Corp.

US Patent
LigandPNGBDBM104688(US8569311, 2-1)
Show SMILES Cc1ccc(c(c1)C(=O)N1CCCC(COc2ccc(F)nc2)C1)-n1nccn1
Show InChI InChI=1S/C21H22FN5O2/c1-15-4-6-19(27-24-8-9-25-27)18(11-15)21(28)26-10-2-3-16(13-26)14-29-17-5-7-20(22)23-12-17/h4-9,11-12,16H,2-3,10,13-14H2,1H3
Affinity DataKi:  96nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid