BDBM10470 Bis-THA inhibitor 1d::Bis-THA inhibitor 9::CHEMBL386423::N-[10-(1,2,3,4-tetrahydroacridin-9-ylamino)decyl]-1,2,3,4-tetrahydroacridin-9-amine

SMILES C(CCCCCNc1c2CCCCc2nc2ccccc12)CCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=CRXRFHPFIFVXJP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10470   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  3.10nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  440nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  40nMAssay Description:Inhibition of rat brain AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  167nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  167nMAssay Description:Inhibition of rat serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Mayo Foundation

LigandPNGBDBM10470(Bis-THA inhibitor 1d | Bis-THA inhibitor 9 | CHEMB...)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed