BDBM10489 1-(5-{[(1-chloro-7,8,9,10-tetrahydro-6H-cyclohepta[b]quinolin-11-yl)amino]methyl}thien-2-yl)-2,2,2-trifluoroethanone::1-{5-[({1-chloro-6H,7H,8H,9H,10H-cyclohepta[b]quinolin-11-yl}amino)methyl]thiophen-2-yl}-2,2,2-trifluoroethan-1-one::N-Alkylated Tacrine Analogue 4

SMILES FC(F)(F)C(=O)c1ccc(CNc2c3CCCCCc3nc3cccc(Cl)c23)s1

InChI Key InChIKey=QNPYGSSPRXBFQL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10489   

TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Syngenta

LigandPNGBDBM10489(1-(5-{[(1-chloro-7,8,9,10-tetrahydro-6H-cyclohepta...)
Affinity DataIC50:  12nMpH: 7.8 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed