BDBM10609 (+)-Physostigmine::(3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate::CHEMBL76640::Physostigmine Carbamate 15b

SMILES CNC(=O)Oc1ccc2N(C)C3N(C)CC[C@]3(C)c2c1

InChI Key InChIKey=PIJVFDBKTWXHHD-AWKYBWMHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10609   

TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  9.89E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  2.49E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  9.89E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  2.49E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  2.49E+3nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10609((+)-Physostigmine | (3aR)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  9.89E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed