BDBM10611 (3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-(2-methylphenyl)carbamate::CHEMBL300143::Physostigmine Carbamate 17a
SMILES CN1CC[C@]2(C)C1N(C)c1ccc(OC(=O)Nc3ccccc3C)cc21
InChI Key InChIKey=JGAGHIIOCADQOV-QWAKEFERSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 10611
Affinity DataIC50: 10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 10.3nMAssay Description:Ability to inhibit acetylcholinesterase (AChE), freshly prepared from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human plasma BChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 10.3nMAssay Description:Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.95E+3nMAssay Description:Ability to inhibit butyrylcholinesterase (BChE), freshly prepared from human plasmaMore data for this Ligand-Target Pair