BDBM10612 (+)-(3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl N-(2-Methylphenyl)carbamate::(3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-(2-methylphenyl)carbamate::Physostigmine Carbamate 17b

SMILES CN1CC[C@@]2(C)C1N(C)c1ccc(OC(=O)Nc3ccccc3C)cc21

InChI Key InChIKey=JGAGHIIOCADQOV-VGAJERRHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10612   

TargetCholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10612((+)-(3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  1.18E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10612((+)-(3aR)-1,3a,8-Trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  5.51E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed