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BDBM106596 US8586617, 67

SMILES: CC(C)N(Cc1cnc[nH]1)c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=PQFOICKWRBQKRX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106596   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Trace amine-associated receptor 1 (TAAR1)


(Mus musculus (Mouse))
BDBM106596
PNG
(US8586617, 67)
Show SMILES CC(C)N(Cc1cnc[nH]1)c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C14H16F3N3O/c1-10(2)20(8-11-7-18-9-19-11)12-3-5-13(6-4-12)21-14(15,16)17/h3-7,9-10H,8H2,1-2H3,(H,18,19)
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PC cid
PC sid
UniChem

Similars

US Patent
6.70 -10.4n/an/an/an/an/an/a4



Hoffmann-La Roche Inc

US Patent


Assay Description
Radioligand binding assay: The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-1-naphthyl)-2-imidazoline was used at a concentration equal to the calcula...


US Patent US8586617 (2013)


BindingDB Entry DOI: 10.7270/Q2GF0S56
More data for this
Ligand-Target Pair