BDBM10676 (+)-phenserine::(+)1::(3aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-phenylcarbamate::CHEMBL75919

SMILES CN1CC[C@@]2(C)C1N(C)c1ccc(OC(=O)Nc3ccccc3)cc21

InChI Key InChIKey=PBHFNBQPZCRWQP-ROPPNANJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10676   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM10676((+)-phenserine | (+)1 | (3aR)-1,3a,8-trimethyl-1H,...)
Affinity DataIC50:  3.50E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10676((+)-phenserine | (+)1 | (3aR)-1,3a,8-trimethyl-1H,...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of human ButyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM10676((+)-phenserine | (+)1 | (3aR)-1,3a,8-trimethyl-1H,...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human acetylcholinesterase from erythrocytes (RBC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
National Institute On Aging

Curated by ChEMBL
LigandPNGBDBM10676((+)-phenserine | (+)1 | (3aR)-1,3a,8-trimethyl-1H,...)
Affinity DataIC50:  2.35E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed