BDBM106778 7‐hydroxy‐8‐methyl‐3‐(4‐methylphenyl)‐4H‐chromen‐4‐ one::7-Hydroxy-8,4′-dimethyl-isoflavone (2b)::IR-203

SMILES Cc1ccc(cc1)-c1coc2c(C)c(O)ccc2c1=O

InChI Key InChIKey=XVHOBANISMPTNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 106778   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

LigandPNGBDBM106778(7‐hydroxy‐8‐methyl‐3‐...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM106778(7‐hydroxy‐8‐methyl‐3‐...)
Affinity DataIC50:  1.50E+3nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

LigandPNGBDBM106778(7‐hydroxy‐8‐methyl‐3‐...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed