BDBM10710 3-{[methyl({6-[(9-oxo-9H-xanthen-3-yl)oxy]hexyl})amino]methyl}phenyl N-methylcarbamate::aminoalkoxyaryl deriv. 12a

SMILES CNC(=O)Oc1cccc(CN(C)CCCCCCOc2ccc3c(c2)oc2ccccc2c3=O)c1

InChI Key InChIKey=ZCJVEAQKQPJJOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10710   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

LigandPNGBDBM10710(3-{[methyl({6-[(9-oxo-9H-xanthen-3-yl)oxy]hexyl})a...)
Affinity DataIC50:  1.40nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

LigandPNGBDBM10710(3-{[methyl({6-[(9-oxo-9H-xanthen-3-yl)oxy]hexyl})a...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

LigandPNGBDBM10710(3-{[methyl({6-[(9-oxo-9H-xanthen-3-yl)oxy]hexyl})a...)
Affinity DataIC50:  13.9nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed