BDBM10726 3-[1-(dimethylamino)ethyl]phenyl N,N-dimethylcarbamate::rivastigmine analog 1a

SMILES CC(N(C)C)c1cccc(OC(=O)N(C)C)c1

InChI Key InChIKey=AIHREYCBCYOMLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10726   

TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10726(3-[1-(dimethylamino)ethyl]phenyl N,N-dimethylcarba...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed