BDBM10822 3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-butyl-N-methylcarbamate::Phenethylamine deriv. 52i

SMILES CCCCN(C)C(=O)Oc1cccc(CC(C)NCC#C)c1

InChI Key InChIKey=IYWJZKJJGUCNHL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10822   

TargetAcetylcholinesterase(Homo sapiens (Human))
Teva Pharmaceutical Industries

LigandPNGBDBM10822(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-butyl-N-...)
Affinity DataIC50:  1.22E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10822(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-butyl-N-...)
Affinity DataIC50:  400nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Teva Pharmaceutical Industries

LigandPNGBDBM10822(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-butyl-N-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Teva Pharmaceutical Industries

LigandPNGBDBM10822(3-[2-(prop-2-yn-1-ylamino)propyl]phenyl N-butyl-N-...)
Affinity DataIC50:  2.75E+3nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed