BDBM10882 6-ethoxy-1,3-benzothiazole-2-sulfonamide::CHEMBL18::Ethamide::Ethoxazolamide::Ethoxzolamide::Ethoxzolamide (EZA)::Ethoxzolamide, EZM::Sulfonamide, 3::US10172837, Ethoxyzolamide::sulfonamide 3
SMILES CCOc1ccc2nc(sc2c1)S(N)(=O)=O
InChI Key InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 398 hits for monomerid = 10882
Affinity DataKi: 0.490nMAssay Description:In vitro binding to human erythrocyte carbonic anhydrase was determined by fluorescence competition assay employing the fluorescent CA inhibitor dans...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 0.780nMAssay Description:Ki value against human carbonic anhydrase VIIMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human carbonic anhydrase 7More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human full length carbonic anhydrase 7 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of full length human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 7 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant carbonic anhydrase 7 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of human recombinant full length CA7 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: <1nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Inhibition of recombinant Thiomicrospira crunogena XCL-2 carbonic anhydrase by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Mean inhibitory constant towards human carbonic anhydrase II determined by stopped-flow methodMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase-2 assessed as reduction in CO2 hydration preincubated for 15 mins followed by CO2 addition measured for 10 to ...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human CA2 cytosolic isoform after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stop flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human cloned isoenzyme carbonic anhydrase II (hCA II), by esterase method.More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human cloned carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against Human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory constant against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against cytosolic human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:In vitro inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human carbonic anhydrase II (hCAII)More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli BL21More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Binding affinity towards human cloned carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibitory activity against human Carbonic anhydrase IIMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human recombinant CA2More data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Ki value against human carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair