BDBM10905 3-Amino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyridin-2(1H)-one::3-amino-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::4-benzyl pyridinone derivative 8b::CHEMBL57733

SMILES CCc1c(C)[nH]c(=O)c(N)c1Cc1cc(C)cc(C)c1

InChI Key InChIKey=PVZMRETVOJGNDW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10905   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Institut Curie

Curated by ChEMBL
LigandPNGBDBM10905(3-Amino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyr...)
Affinity DataEC50:  17nMAssay Description:Effective concentration required to achieve 50% inhibition of HIV-1 LAI replication in human T4 lymphoblastoid CEM-SS cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Institut Curie

LigandPNGBDBM10905(3-Amino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyr...)
Affinity DataIC50:  100nMpH: 8.0 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed